Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
in these sections
Search Forms
Pathology Images
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
[not specified]-Trp53tm2.1Tyj/+
Strain Synonyms p53R172H/+
Strain Note: Heterozygous mice. The full genetic background was not specified but was reported to be predominantly 129S4/SvJae. It may have also included some 129S2/SvPas.
Strain Tumor Overview Expanded View
Tumors 14 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 18
Bone osteosarcoma Bone None (spontaneous) 4 48
CNS - Brain - Undifferentiated cell glioblastoma CNS - Brain - Undifferentiated cell None (spontaneous) 1 0
Intestine - Large Intestine - Rectum carcinoma Intestine - Large Intestine - Rectum None (spontaneous) 1 observed
Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte None (spontaneous) 1 6
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte None (spontaneous) 1 3
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 1 9
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 1 3
Lung adenocarcinoma Lung None (spontaneous) 2 9
Pancreas carcinoma Pancreas None (spontaneous) 1 observed
(Unspecified organ) adenoma (Unspecified organ) None (spontaneous) 1 9
(Unspecified organ) carcinoma (Unspecified organ) None (spontaneous) 1 24
(Unspecified organ) lesion (Unspecified organ) None (spontaneous) 1 24
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 100
Other Database Links
Information about mice carrying the same mutant allele(s):
NCI Mouse Repository