Strain SummarySTOCK Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/?

Strain Name

STOCK Ptentm2Mak Speer6-ps1Tg(Alb-cre)21Mgn/?

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

AlbCrePtenflox/flox  •  flox/flox  •  STOCK Ptentm2Mak Tg(Alb-cre)21Mgn

Description

Transgenic mice which were also homozygous for conditional Ptentm2Mak allele. The genetic background of these mice was primarily C57BL/6 with additional contributions from 129P2/OlaHsd and DBA/2.

Strain Genetics

Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Liver adenoma Liver

30 - 100

67 - 100

References: Horie Y, J Clin Invest 2004 Jun;113(12):1774-83

Liver hepatocellular carcinoma Liver

50

83

67

References: Horie Y, J Clin Invest 2004 Jun;113(12):1774-83

Sites of Metastasis: Lung

Liver hyperplasia Liver

observed

References: Horie Y, J Clin Invest 2004 Jun;113(12):1774-83

Liver tumor Liver

100

100

References: Horie Y, J Clin Invest 2004 Jun;113(12):1774-83