Strain SummaryB6;129-Cdh1tm1Kem/Cdh1tm2Kem Egr2tm2(cre)Pch/+

Strain Name

B6;129-Cdh1tm1Kem/Cdh1tm2Kem Egr2tm2(cre)Pch/+

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)

Strain Synonym(s)

B6;129-Cdh1tm1Kem/tm2Kem Egr2tm2(cre)Pch/+  •  Krox20Cre/+; E-cad-/lox  •  Krox20+/Cre; E-cad-/lox


These mice carried the Cdh1tm1Kem & Cdh1tm2Kem alleles & were het for Egr2tm2(cre)Pch. Genetic background was a mixture of C57BL/6 and "129" (including at least 129S2/SvPas, 129X1/SvJ, and 129S1/Sv).

Strain Genetics

Egr2tm2(cre)Pch / Egr2+
Egr2tm2(cre)Pch / Egr2+
Cdh1tm1Kem / Cdh1tm2Kem


2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin metaplasia - squamous Skin


References: Young P, EMBO J 2003 Nov 3;22(21):5723-33

Skin tumor Skin


References: Young P, EMBO J 2003 Nov 3;22(21):5723-33