Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
Strain Synonyms p53-deficient  •  p53 null (-/-)  •  VM (-/-)  •  VM.129(B6)-Trp53tm1Brd  •  VM congenic p53 null (-/-)
Strain Note: Homozygotes. This mutation had been backcrossed onto VM. The mutant allele was originally generated in "129/Sv" and had been crossed to C57BL/6 prior to the backcrossing.
Strain Tumor Overview Expanded View
Tumors 11 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 3 18
Bone osteosarcoma Bone None (spontaneous) 1 4.55
CNS - Brain - Astrocyte astrocytoma - anaplastic CNS - Brain - Astrocyte None (spontaneous) 1 0
CNS - Meninges meningioma CNS - Meninges None (spontaneous) 1 4.55
Germ cell (sex not specified) teratoma Germ cell (sex not specified) None (spontaneous) 1 4.55
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon None (spontaneous) 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous) 1 0
Leukocyte lymphoma - non-Hodgkin Leukocyte None (spontaneous) 1 77
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 0
Prostate gland tumor Prostate gland None (spontaneous) 1 0
(Unspecified organ) tumor - undifferentiated (Unspecified organ) None (spontaneous) 1 0