Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-12-01
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
B6;129-Trp53tm1Brd
Strain Synonyms C57B6/129Sv (-/-)  •  C57B6/129Sv mixed p53 null (-/-)  •  TSG-p53-/-  •  p53-deficient  •  p53 null (-/-)  •  p53-/-  •  TSG-p53  •  TSG-p53-null
Strain Note: Homozygous mice. The genetic background of these mice was a mixture of C57BL/6 and "129/Sv" (substrain not specified but included at least some 129S7/SvEvBrd-Hprt1+). These mice were from Taconic.
Strain Tumor Overview Expanded View
Tumors 17 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 4.35
Bone osteosarcoma Bone None (spontaneous) 1 0
CNS - Brain - Astrocyte astrocytoma - anaplastic CNS - Brain - Astrocyte None (spontaneous) 1 4.35
CNS - Brain glioma CNS - Brain Genetic Modification 1 observed
CNS - Brain tumor CNS - Brain Genetic Modification 1 89.47
CNS - Brain tumor CNS - Brain Virus 1 0
CNS - Meninges meningioma CNS - Meninges None (spontaneous) 1 0
Germ cell (sex not specified) teratoma Germ cell (sex not specified) None (spontaneous) 1 0
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon None (spontaneous) 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous) 1 0
Leukocyte lymphoma - non-Hodgkin Leukocyte None (spontaneous) 16 91
Leukocyte lymphoma - non-Hodgkin Thymus None (spontaneous) 1 26
Leukocyte lymphoma - non-Hodgkin Spleen None (spontaneous) 1 52
Leukocyte lymphoma - non-Hodgkin Lymph node None (spontaneous) 1 13
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 8.7
Prostate gland tumor Prostate gland None (spontaneous) 1 0
(Unspecified organ) tumor - undifferentiated (Unspecified organ) None (spontaneous) 1 4.35