Strain SummarySTOCK Apctm1Rak/+ Fen1tm1Rak/+

Strain Name

STOCK Apctm1Rak/+ Fen1tm1Rak/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

+/-;+/-  •  Fen1+/-Apc1638N  •  Fen1 +/- Apc +/-  •  Fen1null Apc1638N  •  Fen1null/Apc1638N  •  Fen1null/Apc1638N double heterozygote

Description

Heterozygous mice. Background was stated to include 60% C57BL/6, 37.5% "129/Sv", and 2.5% SJL/J. Other strains may have been included, authors did not indicate ES cell line used for the original targeted mouse.

Strain Genetics

Apctm1Rak / Apc+
Fen1tm1Rak / Fen1+

Models

11 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenocarcinoma Gastrointestinal tract

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Gastrointestinal tract adenoma - microadenoma Gastrointestinal tract

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Gastrointestinal tract adenoma - tubular Gastrointestinal tract

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Gastrointestinal tract adenoma - tubulovillous Gastrointestinal tract

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Gastrointestinal tract carcinoma Gastrointestinal tract

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Gastrointestinal tract tumor Gastrointestinal tract

100

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Intestine - Large Intestine adenoma Intestine - Large Intestine

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

1 pathology image(s)

Intestine - Small Intestine tumor Intestine - Small Intestine

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

Stomach tumor Stomach

observed

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9

(Unspecified organ) tumor (Unspecified organ)

0

References: Kucherlapati M, Proc Natl Acad Sci U S A 2002 Jul 23;99(15):9924-9