Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-12-08
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
STOCK Tcrbtm1Mom Trp53tm1Brd
Strain Synonyms C57BL/6JJcl Tcrbtml/Mom Trp53tml  •  TCRβ and p53 double-knockout  •  TCRβ-/- p53-/-
Strain Note: Homozygous for Tcrb & Trp53 knockout. Mice were N4 generation backcross onto C57BL/6JJcl. Genetic background also includeed contributions from 129P2/OlaHsd, 129S7/SvEvBrd-Hprt+, 129S6/SvEvTac, 129S7/SvEvBrd, C57BL/6, & Black Swiss.
Strain Tumor Overview Expanded View
Tumors 22 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Intestine - Ileocecal junction adenocarcinoma Intestine - Ileocecal junction None (spontaneous) 1 0
Intestine - Ileocecal junction adenocarcinoma Intestine - Ileocecal junction Bacteria 1 70
Intestine - Ileocecal junction dysplasia Intestine - Ileocecal junction None (spontaneous) 2 0
Intestine - Ileocecal junction dysplasia Intestine - Ileocecal junction Bacteria 2 50 - 70
Intestine - Ileocecal junction hyperplasia Intestine - Ileocecal junction None (spontaneous) 1 10
Intestine - Ileocecal junction hyperplasia Intestine - Ileocecal junction Bacteria 1 60
Intestine - Ileocecal junction lesion Intestine - Ileocecal junction None (spontaneous) 1 observed
Intestine - Ileocecal junction lesion Intestine - Ileocecal junction Bacteria 1 observed
Intestine - Large Intestine - Cecum adenocarcinoma Intestine - Large Intestine - Cecum Bacteria 1 observed
Intestine - Large Intestine - Cecum dysplasia Intestine - Large Intestine - Cecum Bacteria 2 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum Bacteria 1 observed
Intestine - Large Intestine - Colon - Distal lesion Intestine - Large Intestine - Colon - Distal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Distal lesion Intestine - Large Intestine - Colon - Distal Bacteria 1 0
Intestine - Large Intestine - Colon - Medial lesion Intestine - Large Intestine - Colon - Medial None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Medial lesion Intestine - Large Intestine - Colon - Medial Bacteria 1 0
Intestine - Large Intestine - Colon - Proximal adenocarcinoma Intestine - Large Intestine - Colon - Proximal Bacteria 1 0
Intestine - Large Intestine - Colon - Proximal dysplasia Intestine - Large Intestine - Colon - Proximal Bacteria 2 0 - observed
Intestine - Large Intestine - Colon - Proximal hyperplasia Intestine - Large Intestine - Colon - Proximal Bacteria 1 observed
Intestine - Large Intestine - Rectum lesion Intestine - Large Intestine - Rectum None (spontaneous) 1 0
Intestine - Large Intestine - Rectum lesion Intestine - Large Intestine - Rectum Bacteria 1 0
Leukocyte lymphoma Leukocyte None (spontaneous) 1 20
Leukocyte lymphoma Leukocyte Bacteria 1 20