Strain SummaryC57BL/6-Apctm1Rak/+ Msh3tm1Rak

Strain Name

C57BL/6-Apctm1Rak/+ Msh3tm1Rak

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

B6.Cg-Apctm1Rak/+ Msh3tm1Rak  •  Msh3-/-Apc1638N

Description

Compound mutant mice. These mice are the product of an intercross between multiple strains, each on a predominantly C57BL/6 background.

Strain Genetics

Apctm1Rak / Apc+

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenocarcinoma Gastrointestinal tract

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Gastrointestinal tract adenoma - microadenoma Gastrointestinal tract

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Gastrointestinal tract adenoma - tubular Gastrointestinal tract

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Gastrointestinal tract adenoma - villous Gastrointestinal tract

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Gastrointestinal tract tumor Gastrointestinal tract

100

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Intestine - Small Intestine tumor Intestine - Small Intestine

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Skin squamous cell carcinoma Skin

8.3

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42

Stomach tumor Stomach

observed

References: Kuraguchi M, Cancer Res 2001 Nov 1;61(21):7934-42