Strain Summary[not specified]-Apctm1Rak/+ Cdkn1atm1Led/+

Strain Name

[not specified]-Apctm1Rak/+ Cdkn1atm1Led/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Apc1638+/-, p21+/-  •  Apc+/-, p21+/-  •  p21+/-

Description

Mice were heterozygous for both the Apc and Cdkn1a alleles. The genetic background of these mice was not specified but includes contributions from 129P2/OlaHsd, 129S6/SvEvTac, C57BL/6, and NIH Black Swiss.

Strain Genetics

Apctm1Rak / Apc+
Cdkn1atm1Led / Cdkn1a+

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Small Intestine - Duodenum tumor Intestine - Small Intestine - Duodenum

very high

References: Yang WC, Cancer Res 2001 Jan 15;61(2):565-9

Intestine - Small Intestine tumor Intestine - Small Intestine

95

95

References: Yang W, Cancer Res 2001 Aug 15;61(16):6297-302   ⋅   Yang WC, Cancer Res 2001 Jan 15;61(2):565-9

Intestine - Small Intestine tumor Intestine - Small Intestine sulindac

94

References: Yang W, Cancer Res 2001 Aug 15;61(16):6297-302

Intestine - Small Intestine tumor Intestine - Small Intestine Western style

very high

References: Yang WC, Cancer Res 2001 Jan 15;61(2):565-9