Strain SummaryB6;129S7-Trp53tm1Glo/+

Strain Name

B6;129S7-Trp53tm1Glo/+

Strain Type(s)

targeted mutation (knock-in)

Strain Synonym(s)

Δg/+  •  p53R172HΔg/+

Description

Heterozygous mice. The genetic background of these mice was a mixture of C57BL/6 and 129S7/SvEvBrd-Hprt+.

Strain Genetics

Trp53tm1Glo / Trp53+

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue liposarcoma Adipose tissue

2

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: not (Unspecified organ)

Bone osteosarcoma Bone

31

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: (Unspecified organ) , Liver , Lung

5 pathology image(s)

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

20

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: not (Unspecified organ)

Leukocyte lymphoma Leukocyte

18

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: not (Unspecified organ)

Liver hepatocellular carcinoma Liver

7.8

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: Lung

2 pathology image(s)

Lung adenocarcinoma Lung

observed

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: Muscle - Striated - Cardiac

2 pathology image(s)

Pancreas - Islet of Langerhans carcinoma Pancreas - Islet of Langerhans

2

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: (Unspecified organ)

(Unspecified organ) adenocarcinoma (Unspecified organ)

10

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

(Unspecified organ) adenoma (Unspecified organ)

2

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

(Unspecified organ) angiosarcoma (Unspecified organ)

5.9

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

Sites of Metastasis: not (Unspecified organ)

(Unspecified organ) carcinoma - poorly differentiated (Unspecified organ)

2

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

(Unspecified organ) squamous cell carcinoma (Unspecified organ)

40

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9

(Unspecified organ) tumor (Unspecified organ)

84

References: Liu G, Proc Natl Acad Sci U S A 2000 Apr 11;97(8):4174-9