Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
in these sections
Search Forms
Pathology Images
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
B6;129-H2axtm1Fwa Trp53tm1Brd
Strain Synonyms B6;129-H2afxtm1Fwa Trp53tm1Brd  •  H2AXΔ/Δp53-/-  •  HΔ/ΔP-/-
Strain Note: Mice were homozygous for both H2axtm1Fwa and Trp53tm1Brd. The genetic background of these mice was a mixture of C57BL/6, 129S6/SvEvTac, 129S7/SvEvBrd-Hprt+, and possibly some other 129/Sv.
Strain Tumor Overview Expanded View
Tumors 7 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon None (spontaneous) 1 5.9
Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte None (spontaneous) 8 observed - 18
Leukocyte - Lymphocyte - Pro-B-lymphocyte lymphoma Leukocyte - Lymphocyte - Pro-B-lymphocyte None (spontaneous) 2 observed
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus None (spontaneous) 4 observed - 71
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 2 observed - 18
Testis - Germ cell teratoma Testis - Germ cell None (spontaneous) 1 0
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 94