Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
B6;129-Parp1tm1Zqw Trp53tm1Brd
Strain Synonyms B6;129-Adprt1tm1Zqw Trp53tm1Brd  •  PARP-1/p53 double null  •  PARP-1-/-p53-/-
Strain Note: Mice homozygous for Adprt1tm1Zqw & Trp53tm1Brd. The genetic background of these mice was a mixture of C57BL/6, 129S2/SvPas, 129S7/SvEvBrd-Hprt+, and possibly an unspecified 129/Sv substrain.
Strain Tumor Overview Expanded View
Tumors 6 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
CNS - Brain - Cerebellum preneoplastic lesion CNS - Brain - Cerebellum None (spontaneous) 1 13
CNS - Brain - Cerebrum tumor CNS - Brain - Cerebrum None (spontaneous) 1 1.6
CNS - Brain - Undifferentiated cell medulloblastoma CNS - Brain - Cerebellum None (spontaneous) 3 observed - 48
CNS - Brain tumor CNS - Brain None (spontaneous) 1 49
Leukocyte lymphoma Leukocyte None (spontaneous) 1 high
(Unspecified organ) angiosarcoma (Unspecified organ) None (spontaneous) 1 high