Strain SummaryB6;129S-Brca2tm1Hst

Strain Name

B6;129S-Brca2tm1Hst

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

brca2lex1/lex1

Description

Mice homozygous for a hypomorphic targeted mutation of Brca2. The genetic background was a mixture of C57BL/6, 129S7/SvEvBrd-Hprtb-m2, and "129/SvEv".

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Bone osteosarcoma Bone

1.9

References: Donoho G, Genes Chromosomes Cancer 2003 Apr;36(4):317-31

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon

1.9

References: Donoho G, Genes Chromosomes Cancer 2003 Apr;36(4):317-31

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte

3.8

References: Donoho G, Genes Chromosomes Cancer 2003 Apr;36(4):317-31

Liver hepatocellular carcinoma Liver

3.8

References: Donoho G, Genes Chromosomes Cancer 2003 Apr;36(4):317-31