Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-12-01
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
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Strain
B6;129S7-Rb1tm1Brd/+ Trp53tm1Brd
Strain Synonyms p53-/- Rb+/-
Strain Note: Mice were heterozygous for the Rb1tm1Brd allele and homozgyous for the Trp53tm1Brd allele. The genetic background of these mice was a mixture of C57BL/6 and 129S7/SvEvBrd-Hprt+.
Strain Tumor Overview Expanded View
Tumors 11 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records		 Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 11
Bone osteosarcoma Bone None (spontaneous) 1 0
CNS - Meninges tumor - malignant CNS - Meninges None (spontaneous) 1 3.7
Leukocyte lymphoma Leukocyte None (spontaneous) 1 41
Mesodermal cell/mesoblast sarcoma - pleomorphic Mesodermal cell/mesoblast None (spontaneous) 1 3.7
Pancreas - Islet of Langerhans carcinoma Pancreas - Islet of Langerhans None (spontaneous) 1 7.4
Parathyroid gland tumor Parathyroid gland None (spontaneous) 1 0
Pineal gland pineoblastoma Pineal gland None (spontaneous) 1 0
Pituitary gland adenoma Pituitary gland None (spontaneous) 1 33
Thyroid gland - Medulla carcinoma Thyroid gland - Medulla None (spontaneous) 1 3.7
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 1 100