Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
STOCK Cdkn2atm1.1Brn/Cdkn2atm2.1Brn
Strain Synonyms */Δ2,3  •  Ink4a*/Δ2,3
Strain Note: These mice carried two targeted mutations of Cdkn2a. They were nullizygous for Inka4 & heterozygous for loss of function of p19Arf. The genetic background was a mixture of 129P2/OlaHsd, FVB/N, and a third unspecified strain.
Strain Tumor Overview Expanded View
Tumors 13 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Connective tissue - Fibroblast fibrosarcoma Skin None (spontaneous) 1 10
Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte None (spontaneous) 1 10
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte None (spontaneous) 1 10
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 1 20
Lung adenocarcinoma Lung None (spontaneous) 1 20
Lung adenocarcinoma Lung Chemical/Drug 1 observed
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous) 1 10
Skin - Melanocyte melanoma Skin - Melanocyte None (spontaneous) 1 10
Skin - Melanocyte melanoma Skin - Melanocyte Chemical/Drug 1 50
Skin carcinoma Skin None (spontaneous) 1 10
Skin papilloma Skin Chemical/Drug 1 observed
Uterus carcinoma Uterus None (spontaneous) 1 10
(Unspecified organ) angiosarcoma (Unspecified organ) None (spontaneous) 1 10