Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
Strain Synonyms Black Swiss;129S-Trp53tm1Brd  •  p53 null  •  p53-/-  •  p53-/- null
Strain Note: Homozygous mice. The genetic background of these mice was a mixture of Black Swiss, 129S7/SvEvBrd-Hprt+, 129S6/SvEvTac, and 129/SvEv (substrain not specified).
Strain Tumor Overview Expanded View
Tumors 15 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 1 16
Blood vessel hemangiosarcoma Heart None (spontaneous) 1 0
Connective tissue - Cartilage chondrosarcoma Mouth None (spontaneous) 1 0
Intestine - Large Intestine - Rectum adenoma Intestine - Large Intestine - Rectum None (spontaneous) 1 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 1 5.3
Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) None (spontaneous) 1 21
Leukocyte lymphoma Leukocyte None (spontaneous) 1 11
Mesodermal cell/mesoblast sarcoma Bone - Jaw None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Salivary gland None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma - spindle cell Bone - Jaw None (spontaneous) 1 0
Ovary - Germ cell teratoma Ovary - Germ cell None (spontaneous) 1 0
Pericyte hemangiopericytoma Bone - Jaw None (spontaneous) 1 0
Thymus - Cortex hyperplasia Thymus - Cortex None (spontaneous) 1 0
Thymus thymoma Thymus None (spontaneous) 1 26
(Unspecified organ) lesion (Unspecified organ) None (spontaneous) 1 50