Strain Summary[not specified]-Cdkn2atm1Rdp Tg(tetO-HRAS)#Lc Tg(Tyr-rtTA)37Lc

Strain Name

[not specified]-Cdkn2atm1Rdp Tg(tetO-HRAS)#Lc Tg(Tyr-rtTA)37Lc

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

[not specified]-Tg(TetO-HRAS)65,72Lc Tg(Tyr-rtTA)37Lc Cdkn2atm1Rdp  •  [not specified]-Tg(tetO-HRAS)#Lc Tg(Tyr-rtTA)37Lc Cdkn2atm1Rdp  •  Tyr-rtTA Tet-Ras INK4a-/-  •  Tyr/Tet-RAS INK4a-/-

Description

Double-transgenic mice homozygous for a targeted mutation of Cdkn2a (INK4a). Mice were derived from either of two HRAS-transgenic founders, no. 65 or 72. The genetic background was not specified.

Strain Genetics

Tg(Tyr-rtTA)37Lc
Tg(Tyr-rtTA)37Lc
Tg(tetO-HRAS)#Lc

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin - Melanocyte melanoma Skin - Melanocyte doxycycline

25

References: Chin L, Nature 1999 Jul 29;400(6743):468-72

Skin - Melanocyte melanoma Skin - Melanocyte

0

References: Chin L, Nature 1999 Jul 29;400(6743):468-72