Mouse Tumor Biology Database (MTB)
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Last Database Update
MTB 3.0
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
Strain Synonyms ARF+/-  •  ARF+/-
Strain Note: Heterozygous mice. The genetic background is a mixture of C57BL/6 and 129X1/SvJ. (Note: This is a targeted mutation of exon 1beta of the Cdkn2a gene and therefore this mutation only affects p19ARF and not p16INK4a.)
Strain Tumor Overview Expanded View
Tumors 18 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Blood vessel hemangioma Blood vessel None (spontaneous) 1 17
Blood vessel hemangioma Liver None (spontaneous) 1 8.3
Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte None (spontaneous) 1 17
Leukocyte lymphoma Leukocyte None (spontaneous) 1 8.3
Leukocyte lymphoma Leukocyte Radiation 1 6.25
Lung adenocarcinoma Lung None (spontaneous) 1 8.3
Lung adenocarcinoma Lung Chemical/Drug 1 7.7
Lymphatic vessel lymphangioma Lymphatic vessel None (spontaneous) 1 8.3
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 1 8.3
Mammary gland carcinoma Mammary gland Radiation 1 6.25
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast None (spontaneous) 1 17
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast Radiation 1 12.5
PNS - Schwann cell tumor CNS - Spinal cord Chemical/Drug 1 7.7
Skin squamous cell carcinoma Skin None (spontaneous) 1 8.3
Skin squamous cell carcinoma Skin Chemical/Drug 1 23
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 3 0 - 92
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug 2 0 - 38
(Unspecified organ) tumor (Unspecified organ) Radiation 2 12.5 - 25
Other Database Links
Information about mice carrying the same mutant allele(s):
NCI Mouse Repository
NCI Mouse Repository