Strain SummaryC57BL/6 +/+ : 129S2/SvPas-Nf1tm1Tyj/Nf1tm2Tyj Gt(ROSA)26Sor

Strain Name

C57BL/6 +/+ : 129S2/SvPas-Nf1tm1Tyj/Nf1tm2Tyj Gt(ROSA)26Sor

Strain Type(s)

chimeric  •  gene trapped  •  targeted mutation (knockout)

Strain Synonym(s)

C57BL/6 +/+: 129S2/SvPas-Nf1tm1Tyj/Nf1tm2TyjGtrosa26  •  C57BL/6 +/+ : 129S2/SvPas-Nf1tm1Tyj/tm2Tyj Gt(ROSA)26Sor  •  Nf1+/+:Nf1-/-;ROSA-26+/-

Description

Chimeras generated by injection into C57BL/6 blastocysts of double gene-targeted ES cells transgenic for LacZ [Tg(ROSA26)26Sor].

Strain Genetics

Gt(ROSA)26Sor
Nf1tm1Tyj / Nf1tm2Tyj

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
PNS - Schwann cell neurofibroma - plexiform PNS - Nerve sheath

67

References: Cichowski K, Science 1999 Dec 10;286(5447):2172-6