Strain SummaryB6;129-ApcMin/+ Pms2tm1Lisk

Strain Name

B6;129-ApcMin/+ Pms2tm1Lisk

Strain Type(s)

chemically induced mutation  •  targeted mutation (knockout)

Strain Synonym(s)

B6,129-Pms2tm1Lisk ApcMin/+  •  B6;129-Pms2tm1Lisk ApcMin/+  •  Pms2-/-;Apc+/min  •  Pms2-/-;Min

Description

Mice were heterozygous for the Apc allele and homozygous for the Pms2 allele. The genetic background of these mice was a mixture of C57BL/6, 129S2/SvPas, and possibly some other unspecified 129 substrain.

Strain Genetics

ApcMin / Apc+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract adenoma Gastrointestinal tract

observed

References: Baker SM, Cancer Res 1998 Mar 15;58(6):1087-9

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

observed

References: Baker SM, Cancer Res 1998 Mar 15;58(6):1087-9