Strain SummaryB6;129P2-Apctm1Rak/+ Mlh1tm1Rak/+

Strain Name

B6;129P2-Apctm1Rak/+ Mlh1tm1Rak/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

B6,129-Mlh1tm1Rak/+ Apctm1Rak/+  •  Apc1638 +/-/Mlh1 +/-  •  Mlh1+/-, Apc1638+/-

Description

Heterozygous mice of mixed genetic background (C57BL/6J and 129P2/OlaHsd).

Strain Genetics

Mlh1tm1Rak / Mlh1+
Apctm1Rak / Apc+

Models

4 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Gastrointestinal tract tumor Gastrointestinal tract

77

References: Edelmann W, Cancer Res 1999 Mar 15;59(6):1301-7

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

0

References: Edelmann W, Cancer Res 1999 Mar 15;59(6):1301-7

Leukocyte - Lymphocyte lymphoma - non-Hodgkin Leukocyte - Lymphocyte

15

References: Edelmann W, Cancer Res 1999 Mar 15;59(6):1301-7

Skin carcinoma Skin

7.7

References: Edelmann W, Cancer Res 1999 Mar 15;59(6):1301-7

Sites of Metastasis: Lung