Strain SummaryA/J

Strain Name

A/J

Strain Type(s)

inbred

Strain Synonym(s)

A  •  A/Cloudman  •  AJ  •  A/Jax  •  A/J, H-2a  •  A/J-Jax  •  A/Lilly  •  strain A  •  Strain A

Models

393 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue - White lipoma Adipose tissue - White

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma - pedunculated Peritoneum - Mesentery

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

6 pathology image(s)

Adipose tissue lipoma - pedunculated Adipose tissue

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Cortex hyperplasia - nodular Adrenal gland - Cortex

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Cortex

60

20

References: Kim JS, Exp Anim 1997 Oct;46(4):303-6

Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell

moderate

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia Adrenal gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Adrenal gland hyperplasia - nodular Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - spindle cell Adrenal gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Adrenal gland tumor - carcinoid Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma - capillary Muscle - Striated - Skeletal

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

4 pathology image(s)

Blood vessel hemangioma - cavernous Blood vessel

observed

observed

References: Booth CJ, Lab Anim Sci 1995 Oct;45(5):497-502

Blood vessel hemangiosarcoma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Liver

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone hyperplasia Bone

0 - observed

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone lesion - fibro-osseous Bone

0

0

0

References: Berndt A, Exp Mol Pathol 2015 Nov 14;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Epididymis cyst Epididymis

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte leukemia - erythroleukemia Spleen

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte neoplasm Erythrocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Esophagus hyperplasia Esophagus

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Eye - Harderian gland adenoma Eye - Harderian gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

4 pathology image(s)

Eye - Lacrimal gland hyperplasia Eye - Lacrimal gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Forestomach carcinoma in situ Forestomach N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach carcinoma in situ Forestomach green tea   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach hyperplasia Forestomach N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach hyperplasia Forestomach green tea   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach hyperplasia Forestomach

observed

References: Sundberg J, Personal Communication 1997;():

Forestomach hyperplasia - papillary Forestomach

0 - observed

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach papilloma Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)

observed

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7

Forestomach papilloma Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   myo-inositol

observed

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7

Forestomach papilloma Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   dexamethasone (DEX)

observed

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7

Forestomach papilloma Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   dexamethasone (DEX)   ⋅   myo-inositol

observed

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7

Forestomach papilloma Forestomach

0

References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach papilloma Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

85 - 100

References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46

Forestomach papilloma Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   1,4-phenylenebis(methylene)selenocyanate (p-XSC)

50 - 100

References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46

Forestomach papilloma Forestomach N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach papilloma Forestomach green tea   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach squamous cell carcinoma Forestomach N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach squamous cell carcinoma Forestomach green tea   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach tumor Forestomach

0

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach tumor Forestomach green tea

0

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach tumor Forestomach N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

98 - 100

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Forestomach tumor Forestomach green tea   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

72 - 97

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Gallbladder cyst Gallbladder

0

observed - moderate

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg J, Personal Communication 1997;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

2 pathology image(s)

Gallbladder hyperplasia Gallbladder

0

0 - observed

References: Sundberg J, Personal Communication 1997;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder hyperplasia - papillary Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gastrointestinal tract carcinoma Gastrointestinal tract N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

observed

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum

observed - moderate

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Colon - Distal adenocarcinoma Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50

Intestine - Large Intestine - Colon - Distal adenoma - polypoid Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50   ⋅   Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal squamous cell carcinoma Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50

Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed - 100

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50   ⋅   Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal azoxymethane (AOM)

0

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50   ⋅   Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

References: Guda K, Cancer Lett 2003 Feb 28;191(1):17-25

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

100

References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24

Intestine - Large Intestine tumor Intestine - Large Intestine dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

100

References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24

Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum adenocarcinoma in situ Intestine - Small Intestine - Duodenum

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine normal tissue (control) Intestine - Small Intestine

not applicable

References: Lyons BL, Personal Communication 2004;():

6 pathology image(s)

Intestine - Small Intestine tumor Intestine - Small Intestine

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Intestine - Small Intestine tumor Intestine - Small Intestine azoxymethane (AOM)

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Kidney - Renal tubule adenoma Kidney - Renal tubule

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

4 pathology image(s)

Kidney adenoma Kidney

0

observed - low

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Kidney tumor Kidney

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Kidney tumor Kidney azoxymethane (AOM)

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

1

1

1

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lung

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte leukemia Leukocyte

1.6 - 3.1

References: Myers DD, Life Sci 1970;9(Pt II):1071-80

Leukocyte leukemia Leukocyte Friend leukemia virus - "regressing" (RFV)

70

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte leukemia Leukocyte Friend leukemia virus - "conventional" (CFV)

82

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte lymphoma Leukocyte

0

0

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct adenoma Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct hyperplasia Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver hepatoma Liver

0

0

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver tumor Liver

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Liver tumor Liver azoxymethane (AOM)

0

References: Papanikolaou A, Cancer Lett 1998 Aug 14;130(1-2):29-34

Lung - Alveolus adenoma Lung - Alveolus

0 - 51

34

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22   ⋅   Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5

Lung - Alveolus adenoma Lung - Alveolus theaflavins

0

References: Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5

Lung - Alveolus adenoma Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed - 100

References: Belinsky SA, Cancer Res 1992 Jun 1;52(11):3164-73   ⋅   Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60   ⋅   Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5   ⋅   Yao R, Exp Lung Res 2000 Dec;26(8):731-42

Lung - Alveolus adenoma Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   theaflavins

100

References: Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5

Lung - Alveolus adenoma Lung - Alveolus vinyl chloride (chloroethylene)

74 - 100

88 - 100

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus carbon disulfide

39

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus 1,2-dibromoethane

68 - 100

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus ethylene oxide

42 - 87

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus naphthalene

29 - 30

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus nitrogen dioxide

observed - 12

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus urethane (ethyl carbamate)

100

100

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus adenoma Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin (acetylsalicylic acid) (ASA)

observed - 100

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60   ⋅   Yao R, Exp Lung Res 2000 Dec;26(8):731-42

Lung - Alveolus adenoma Lung - Alveolus acetaminophen   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

100

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60

Lung - Alveolus adenoma Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   NS-398

observed - 100

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60   ⋅   Yao R, Exp Lung Res 2000 Dec;26(8):731-42

Lung - Alveolus adenoma Lung - Alveolus vinyl carbamate (VC)

observed

References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68

Lung - Alveolus carcinoma Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Belinsky SA, Cancer Res 1992 Jun 1;52(11):3164-73

Lung - Alveolus carcinoma Lung - Alveolus vinyl carbamate (VC)

observed

References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68

Lung - Alveolus hyperplasia Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Belinsky SA, Cancer Res 1992 Jun 1;52(11):3164-73   ⋅   Yang G, Cancer Res 1997 May 15;57(10):1889-94   ⋅   Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5

Lung - Alveolus hyperplasia Lung - Alveolus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   theaflavins

observed

References: Yang GY, Carcinogenesis 1997 Dec;18(12):2361-5

Lung - Alveolus hyperplasia Lung - Alveolus 1,2-dibromoethane

observed

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Alveolus hyperplasia Lung - Alveolus vinyl carbamate (VC)

observed

References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68

Lung - Alveolus lesion Lung - Alveolus

0 - 50

References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68

Lung - Alveolus lesion Lung - Alveolus vinyl carbamate (VC)

100

References: Foley JF, Exp Lung Res 1991 Mar-Apr;17(2):157-68

Lung - Bronchiole adenoma Lung - Bronchiole 1,2-dibromoethane

observed

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Bronchiole hyperplasia Lung - Bronchiole 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung - Bronchiole hyperplasia Lung - Bronchiole 1,2-dibromoethane

observed

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung - Club cell carcinoma Lung - Club cell radon

11

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung adenocarcinoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

80

observed

observed

References: Belinsky SA, Carcinogenesis 1997 Jan;18(1):115-20   ⋅   Sabourin CL, Exp Lung Res 1998 Jul-Aug;24(4):499-521   ⋅   Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenocarcinoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   black tea

58

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenocarcinoma Lung 1-nitropyrene (1-NP)

observed

References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64

Lung adenocarcinoma Lung dimethyl sulfoxide (DMSO)

0

References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64

Lung adenocarcinoma Lung urethane (ethyl carbamate)

observed - very high

observed

References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50   ⋅   Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75   ⋅   You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4

Lung adenocarcinoma Lung

0

References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70

Lung adenocarcinoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

25 - 48

References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70

Lung adenocarcinoma - mixed Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenocarcinoma - papillary Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenocarcinoma - solid Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

96 - 100

observed

60 - 100

References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7   ⋅   Devereux TR, Mol Carcinog 1993;8(3):177-85   ⋅   Duperron C, Carcinogenesis 1997 May;18(5):1001-6   ⋅   Lantry LE, Carcinogenesis 2000 Jan;21(1):113-6   ⋅   Sabourin CL, Exp Lung Res 1998 Jul-Aug;24(4):499-521   ⋅   Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7   ⋅   Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenoma Lung tricaprylin

50

References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63

Lung adenoma Lung dibenzo[a,l]pyrene (DB[a,l]P)

43 - 100

References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63

Lung adenoma Lung urethane (ethyl carbamate)

observed - 100

100

observed - 100

References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50   ⋅   Horio Y, Mol Carcinog 1996 Dec;17(4):217-23   ⋅   Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6   ⋅   Malkinson AM, J Natl Cancer Inst 1985 Nov;75(5):971-4   ⋅   Mason RJ, Am J Pathol 2000 Jan;156(1):175-82   ⋅   McNeill DA, Drug Chem Toxicol 1990;13(1):71-86   ⋅   McNeill DA, Drug Chem Toxicol 1990;13(1):87-92   ⋅   Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63   ⋅   Ruch RJ, Exp Lung Res 2001 Apr-May;27(3):231-43   ⋅   Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75   ⋅   Thaete LG, Cancer Lett 1991 Dec 9;61(1):15-20   ⋅   You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

0 - very high

observed

71 - 95

observed - 74

References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7   ⋅   Chen B, Carcinogenesis 1994 Sep;15(9):2031-5   ⋅   Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7   ⋅   Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70   ⋅   Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63   ⋅   Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82   ⋅   You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4

Lung adenoma Lung benzo[b]fluoranthene (B[b]F)

observed

References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63

Lung adenoma Lung cyclopental[c,d]pyrene (CPP)

observed

References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63

Lung adenoma Lung 5-methylchrysene (5-MeC)

observed

References: Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   black tea

100

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung adenoma Lung

0 - high

observed - 80

3.2 - 42

11 - 50

References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50   ⋅   Berndt A, Cancer Res 2011 Sep 1;71(17):5779-91   ⋅   Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7   ⋅   Chen B, Carcinogenesis 1994 Sep;15(9):2031-5   ⋅   D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15   ⋅   Duperron C, Carcinogenesis 1997 May;18(5):1001-6   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20   ⋅   Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8   ⋅   Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70   ⋅   McNeill DA, Drug Chem Toxicol 1990;13(1):71-86   ⋅   McNeill DA, Drug Chem Toxicol 1990;13(1):87-92   ⋅   Prahalad AK, Carcinogenesis 1997 Oct;18(10):1955-63   ⋅   Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46   ⋅   Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

17 pathology image(s)

Lung adenoma Lung uranium ore dust

observed

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung adenoma Lung radon

observed

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung adenoma Lung 1-nitropyrene (1-NP)

very high

References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64

Lung adenoma Lung dimethyl sulfoxide (DMSO)

4.3

References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64

Lung adenoma Lung benzotrichloride (BTC)

observed

References: You M, Carcinogenesis 1993 Jun;14(6):1247-9

Lung adenoma Lung silica

20

References: McNeill DA, Drug Chem Toxicol 1990;13(1):87-92

Lung adenoma Lung nickel subsulfide

0 - 63

References: McNeill DA, Drug Chem Toxicol 1990;13(1):71-86

Lung adenoma Lung N-methyl-N-nitrosourea (MNU)

observed

References: You M, Proc Natl Acad Sci U S A 1989 May;86(9):3070-4

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   FTI-276 (farnesyltransferase inhibitor 276)

58

References: Lantry LE, Carcinogenesis 2000 Jan;21(1):113-6

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   budesonide

observed - very high

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   myo-inositol

observed - very high

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7   ⋅   Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82

Lung adenoma Lung budesonide   ⋅   benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   myo-inositol

observed - very high

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   budesonide   ⋅   myo-inositol

observed - very high

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   beclomethasone dipropionate

very high

References: Wattenberg LW, Carcinogenesis 2000 Feb;21(2):179-82

Lung adenoma Lung environmental cigarette smoke (ECS)

30 - 75

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung environmental cigarette smoke (ECS)   ⋅   halogen light

35 - 55

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung Aroclor 1254

0 - 22

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung Aroclor 1254   ⋅   environmental cigarette smoke (ECS)

0 - 78

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung Aroclor 1254   ⋅   butylated hydroxytoluene (BHT)

0 - 56

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung Aroclor 1254   ⋅   environmental cigarette smoke (ECS)   ⋅   butylated hydroxytoluene (BHT)

0 - 56

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung mainstream cigarette smoke (MCS)

0 - 33

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung adenoma Lung mainstream cigarette smoke condensate (MCSC)

0

References: D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15

Lung adenoma Lung urethane (ethyl carbamate)   ⋅   butylated hydroxytoluene (BHT)

100

References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   dexamethasone (DEX)

very high

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   dexamethasone (DEX)   ⋅   myo-inositol

very high

References: Estensen RD, Carcinogenesis 1993 Sep;14(9):1975-7

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   AIN-76A

13 - 100

References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   NIH-07

4 - 100

References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   NIH-07   ⋅   AIN-76A

100

References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4

Lung adenoma Lung AIN-76A

0 - 30

References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4

Lung adenoma Lung NIH-07

0 - 12

References: Hecht SS, Carcinogenesis 1989 Oct;10(10):1901-4

Lung adenoma Lung dimethylnitrosamine (DMN)

100

References: Chen B, Carcinogenesis 1994 Sep;15(9):2031-5

Lung adenoma Lung 7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12

Lung adenoma Lung calorie restricted   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12

Lung adenoma Lung adrenalectomy   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12

Lung adenoma Lung adrenalectomy   ⋅   calorie restricted   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Pashko LL, Carcinogenesis 1996 Feb;17(2):209-12

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

100

References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   1,4-phenylenebis(methylene)selenocyanate (p-XSC)

40 - 100

References: Prokopczyk B, Cancer Lett 2000 Dec 8;161(1):35-46

Lung adenoma Lung lyophilized strawberries

20 - 30

References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   lyophilized strawberries

95

References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7

Lung adenoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   lyophilized strawberries

79

References: Carlton PS, Cancer Lett 2000 Oct 31;159(2):113-7

Lung adenoma Lung green tea

0 - 5.6

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Lung adenoma Lung N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

94 - 100

observed

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7   ⋅   You M, Carcinogenesis 1992 Sep;13(9):1583-6

Lung adenoma Lung green tea   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

46 - 97

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Lung adenoma Lung black tea - decaffeinated

4.2

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Lung adenoma Lung green tea - decaffeinated

4.0

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   green tea - decaffeinated

66 - 83

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   black tea - decaffeinated

83 - 93

References: Wang ZY, Cancer Res 1992 Apr 1;52(7):1943-7

Lung adenoma Lung N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

observed

References: You M, Carcinogenesis 1992 Sep;13(9):1583-6

Lung adenoma Lung sulindac   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

100

References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin (acetylsalicylic acid) (ASA)

93

References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin - non-buffered

100

References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6

Lung adenoma Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin - buffered

100

References: Duperron C, Carcinogenesis 1997 May;18(5):1001-6

Lung adenoma Lung budesonide   ⋅   benzo[a]pyrene (BP) (BaP) (B[a]P)

0 - observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung carcinoma Lung

0 - 11.11

0 - observed

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22   ⋅   Fenske TS, Cancer Res 2006 May 15;66(10):5029-38   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20   ⋅   Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung carcinoma Lung uranium ore dust

observed

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung carcinoma Lung radon

observed

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung carcinoma Lung 1,2-dibromoethane

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung carcinoma Lung carbon disulfide

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung carcinoma Lung ethylene oxide

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung carcinoma Lung naphthalene

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung carcinoma Lung nitrogen dioxide

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung carcinoma Lung urethane (ethyl carbamate)

0

0 - observed

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22   ⋅   Ruch RJ, Exp Lung Res 2001 Apr-May;27(3):231-43

Lung carcinoma Lung vinyl chloride (chloroethylene)

0

0

References: Adkins B Jr, J Toxicol Environ Health 1986;17(2-3):311-22

Lung carcinoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

0 - observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung carcinoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   budesonide

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung carcinoma Lung budesonide   ⋅   benzo[a]pyrene (BP) (BaP) (B[a]P)

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung carcinoma Lung budesonide   ⋅   benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   myo-inositol

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung carcinoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   myo-inositol

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung carcinoma Lung mainstream cigarette smoke (MCS)

5

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung carcinoma Lung N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

75 - 86

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Lung dysplasia Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

59

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung dysplasia Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   black tea

69

References: Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung hyperplasia Lung radon

observed - 10

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung hyperplasia Lung

0 - observed

0 - observed

References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20   ⋅   Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lung hyperplasia Lung uranium ore dust

observed

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung hyperplasia Lung urethane (ethyl carbamate)

observed

observed

References: Bauer AK, Carcinogenesis 2000 Apr;21(4):543-50   ⋅   Horio Y, Mol Carcinog 1996 Dec;17(4):217-23

Lung hyperplasia Lung 1-nitropyrene (1-NP)

very high

References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64

Lung hyperplasia Lung dimethyl sulfoxide (DMSO)

0

References: Bai F, Mol Carcinog 1998 Aug;22(4):258-64

Lung hyperplasia Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

0 - very high

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70

Lung hyperplasia Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   budesonide

0 - observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung hyperplasia Lung budesonide   ⋅   benzo[a]pyrene (BP) (BaP) (B[a]P)

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung hyperplasia Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   budesonide   ⋅   myo-inositol

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung hyperplasia Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   myo-inositol

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung hyperplasia Lung mainstream cigarette smoke (MCS)

observed

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung metaplasia - squamous Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

very high

References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70

Lung normal tissue (control) Lung urethane (ethyl carbamate)

not applicable

References: Stearman RS, Am J Pathol 2005 Dec;167(6):1763-75

Lung papilloma Lung

0

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung papilloma Lung mainstream cigarette smoke (MCS)

0

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung squamous cell carcinoma Lung

0

References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70

Lung squamous cell carcinoma Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

48 - 50

References: Kim SH, Anticancer Res 1996 Jan-Feb;16(1):465-70

Lung tumor Lung

0 - 100

0 - 81

observed - 59.0

observed - 90

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15   ⋅   D'Agostini F, Int J Oncol 2001 Mar;18(3):607-15   ⋅   Devereux TR, Mol Carcinog 1993;8(3):177-85   ⋅   Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20   ⋅   Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53   ⋅   Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8   ⋅   Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72   ⋅   Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831   ⋅   Russell ES, 1966;():511-519   ⋅   Ryan J, J Natl Cancer Inst 1987 Dec;79(6):1351-7   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35   ⋅   Smith GS, J Natl Cancer Inst 1973 May;50(5):1195-213   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Staats J, Companion to Mouse News Lett No. 25 1961;():   ⋅   Witschi H, Carcinogenesis 1997 Mar;18(3):575-86   ⋅   You L, Carcinogenesis 1994 Nov;15(11):2613-8   ⋅   You M, Carcinogenesis 1992 Sep;13(9):1583-6   ⋅   You M, Proc Natl Acad Sci U S A 1992 Jul 1;89(13):5804-8

Lung tumor Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed - 100

observed - very high

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15   ⋅   Devereux TR, Carcinogenesis 1991 Feb;12(2):299-303   ⋅   Devereux TR, Mol Carcinog 1993;8(3):177-85   ⋅   Malkinson AM, Carcinogenesis 1998 Aug;19(8):1353-6   ⋅   Yang G, Cancer Res 1997 May 15;57(10):1889-94

Lung tumor Lung uranium ore dust

0 - 60

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung tumor Lung radon

10 - 72

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung tumor Lung urethane (ethyl carbamate)

100

observed - 100

observed - 100

References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93   ⋅   Devereux TR, Mol Carcinog 1993;8(3):177-85   ⋅   Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32   ⋅   Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8   ⋅   Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung environmental tobacco smoke (ETS)

25 - 83

References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung urethane (ethyl carbamate)   ⋅   environmental tobacco smoke (ETS)

100

References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung 3-methylcholanthrene (MCA) (3-MC)

100

observed

References: Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32   ⋅   Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung 3-methylcholanthrene (MCA) (3-MC)   ⋅   environmental tobacco smoke (ETS)

100

References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung butylated hydroxytoluene (BHT)   ⋅   environmental tobacco smoke (ETS)

76

References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung butylated hydroxytoluene (BHT)

56

References: Witschi H, Carcinogenesis 1997 Mar;18(3):575-86

Lung tumor Lung vinyl carbamate (VC)

observed - 100

very high

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72   ⋅   You M, Proc Natl Acad Sci U S A 1992 Jul 1;89(13):5804-8

Lung tumor Lung nitrogen mustard (HN2)

29 - 95

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung mannitol mustard

41 - 91

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung cyclophosphamide (Cytoxan)

40 - 74

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung melphalan (L-phenylalanine mustard) (L-sarcolysin)

40 - 98

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung chlorambucil mustard

47 - 100

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung uracil mustard

56 - 100

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung benzalpurine mustard (Elderfield purine mustard)

19 - 45

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung naphthylamine mustard

40 - 100

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung aniline mustard

67 - 100

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung hydroquinone mustard (Weatherbee mustard)

44 - 64

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung benzimidazole mustard

26 - 100

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung chloroquine mustard

20 - 80

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung chloroquine mustard pamoate

27 - 48

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 5-chloroquine mustard

17 - 45

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 5-chloroquine mustard pamoate

24 - 58

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung quinacrine ethyl mustard/2

20 - 67

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung quinacrine ethyl mustard

24 - 67

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung quinacrine propyl mustard/2

23 - 37

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung quinacrine propyl mustard

15 - 30

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung quinacrine mustard

23 - 46

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung OPSPA

39 - 83

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung thioTEPA (thio-TEPA) (TESPA)

29 - 83

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung aziridyl benzoquinone

36 - 86

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung mannitol myleran

27 - 100

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung chloroethylmesulfan

24 - 59

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung diepoxybutane (L-butadiene epoxide)

21 - 78

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung diepoxypiperazine

27 - 62

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung epoxypropidine

14 - 48

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung epodyl (diglycidyltriethylene glycol)

14 - 71

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Lung tumor Lung 7H-dibenzo[c,g]carbazole (3,4,5,6-dibenzocarbazole) (DBC)

89 - 100

References: Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53

Lung tumor Lung benzo[a]pyrene (BP) (BaP) (B[a]P)

observed

29 - 100

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15   ⋅   Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201   ⋅   Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53

Lung tumor Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   7H-dibenzo[c,g]carbazole (3,4,5,6-dibenzocarbazole) (DBC)

33 - 100

References: Gray DL, Exp Lung Res 2001 Apr-May;27(3):245-53

Lung tumor Lung vinyl carbamate (VC)   ⋅   myo-inositol

observed - 100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung dexamethasone (DEX)   ⋅   vinyl carbamate (VC)

observed - 100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung vinyl carbamate (VC)   ⋅   dexamethasone (DEX)

75 - 100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung piroxicam   ⋅   vinyl carbamate (VC)

observed - 100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung alpha-difluoromethylornithine (DFMO)   ⋅   vinyl carbamate (VC)

100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung green tea extract   ⋅   vinyl carbamate (VC)

100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung alpha-difluoromethylornithine (DFMO)   ⋅   vinyl carbamate (VC)   ⋅   dexamethasone (DEX)

86

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung green tea extract   ⋅   dexamethasone (DEX)   ⋅   vinyl carbamate (VC)

79

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung piroxicam   ⋅   dexamethasone (DEX)   ⋅   vinyl carbamate (VC)

86

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung alpha-difluoromethylornithine (DFMO)   ⋅   green tea extract   ⋅   vinyl carbamate (VC)

100

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung piroxicam   ⋅   alpha-difluoromethylornithine (DFMO)   ⋅   vinyl carbamate (VC)

93

References: Gunning WT, Exp Lung Res 2000 Dec;26(8):757-72

Lung tumor Lung 5-methylchrysene (5-MeC)

65 - 100

References: You L, Carcinogenesis 1994 Nov;15(11):2613-8

Lung tumor Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   sulindac sulfone

61 - 93

References: Malkinson AM, Carcinogenesis 1998 Aug;19(8):1353-6

Lung tumor Lung budesonide

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung tumor Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   budesonide

observed

References: Estensen RD, Carcinogenesis 2004 Feb;25(2):197-201

Lung tumor Lung 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin (acetylsalicylic acid) (ASA)

observed - 100

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15

Lung tumor Lung sulindac   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15

Lung tumor Lung A-79175   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

80

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15

Lung tumor Lung A-79175   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin (acetylsalicylic acid) (ASA)

76

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15

Lung tumor Lung naproxen   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

observed

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15

Lung tumor Lung benzo[a]pyrene (BP) (BaP) (B[a]P)   ⋅   sulindac

observed

References: Castonguay A, Exp Lung Res 1998 Jul-Aug;24(4):605-15

Lung tumor Lung mainstream cigarette smoke (MCS)

observed - 60

References: Gordon T, Cancer Lett 2009 Mar 18;275(2):213-20

Lung tumor Lung 3-methylcholanthrene (MCA) (3-MC)   ⋅   butylated hydroxytoluene (BHT)

observed

References: Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32

Lymph node cyst Lymph node

observed - moderate

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymph node hyperplasia Reticulocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mammary gland adenocarcinoma Mammary gland

1 - 28

0

1

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831   ⋅   Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Mammary gland tumor Mammary gland

1 - moderate

20 - moderate

References: International Nomenclature Committee, Cancer Res 1952 Aug;12(8):602-13   ⋅   Russell ES, 1966;():511-519   ⋅   Smith GS, J Natl Cancer Inst 1973 May;50(5):1195-213   ⋅   Staats J, Cancer Res 1985 Mar;45(3):945-77   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():   ⋅   Staats J, Companion to Mouse News Lett No. 25 1961;():

Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Seminal vesicle

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Urinary bladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesothelium mesothelioma Peritoneal cavity

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Mouth - Oral mucosa cyst Mouth - Oral mucosa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyoma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Striated - Skeletal lesion Muscle - Striated - Skeletal

observed

References: Sher RB, PLoS One 2011;6(8):e23498

Muscle - Striated - Skeletal neoplasm Muscle - Striated - Skeletal

observed

References: Sher RB, PLoS One 2011;6(8):e23498

Muscle - Striated - Skeletal normal tissue (control) Muscle - Striated - Skeletal

not applicable

References: Sher RB, PLoS One 2011;6(8):e23498

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

0 - observed

observed - low

observed

observed

References: Sher RB, PLoS One 2011;6(8):e23498   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg J, Personal Communication 1997;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

30 pathology image(s)

Muscle - Striated - Skeletal rhabdomyosarcoma CNS - Spinal cord

observed

References: Sundberg J, Personal Communication 1997;():

3 pathology image(s)

Muscle - Striated - Skeletal rhabdomyosarcoma Leg

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Muscle - Striated - Skeletal rhabdomyosarcoma Bone - Vertebral column

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal

0 - 78.95

0 - 70

0 - 75.86

References: Sher RB, PLoS One 2011;6(8):e23498

16 pathology image(s)

Muscle - Striated - Skeletal rhabdomyosarcoma - well differentiated Muscle - Striated - Skeletal

observed

References: Sundberg J, Personal Communication 1997;():

2 pathology image(s)

Muscle - Striated - Skeletal tumor Muscle - Striated - Skeletal

observed

References: Sher RB, PLoS One 2011;6(8):e23498

Myoepithelial cell myoepithelioma Myoepithelial cell

1

1

sporadic

References: Festing MFW, Mouse Genome 1996;94(3):523-677   ⋅   Sundberg JP, Vet Pathol 1991 Jul;28(4):313-23

Myoepithelial cell myoepithelioma Mammary gland

0

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Sites of Metastasis: Lung

6 pathology image(s)

Myoepithelial cell myoepithelioma Blood vessel

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

1 pathology image(s)

Myoepithelial cell myoepithelioma Lung

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Nail squamous cell carcinoma Nail

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Follicle cyst - follicular Ovary - Follicle

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Granulosa cell tumor Ovary - Granulosa cell

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Sites of Metastasis: Lung

Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Luteal cell tumor Ovary - Luteal cell

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary adenoma Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary cyst Ovary

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Ovary cyst - bursal Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary hyperplasia - epithelial Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary tumor - tubulostromal Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor - malignant Subcutis

observed

References: Mikaelian I, Personal Communication 2004;():

9 pathology image(s)

Pancreas - Duct adenoma Pancreas - Duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Pancreas carcinoma in situ Pancreas

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Salivary gland carcinoma Salivary gland

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis cyst - inclusion Skin - Epidermis

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin tumor Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

64

References: Sundberg JP, Mol Carcinog 1997 SEP;20(1):19-32

Spleen hyperplasia Spleen

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Stomach - Glandular adenoma Stomach - Glandular

0 - observed

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst - glandular Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular polyp Stomach - Glandular

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach papilloma Stomach

observed - low

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60   ⋅   Sundberg J, MGI Direct Data Submission 2007;():

Stomach papilloma Stomach 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

low

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60

Stomach papilloma Stomach 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   aspirin (acetylsalicylic acid) (ASA)

low

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60

Stomach papilloma Stomach acetaminophen   ⋅   4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

low

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60

Stomach papilloma Stomach 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)   ⋅   NS-398

low

References: Rioux N, Cancer Res 1998 Dec 1;58(23):5354-60

Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Thymus thymoma Thymus

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Thyroid gland hyperplasia - cystic Thyroid gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter - Transitional cell hyperplasia Ureter - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter hyperplasia Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter polyp Ureter

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder papilloma Urinary bladder uracil mustard

1

References: Shimkin MB, J Natl Cancer Inst 1966;36():915-35

Urinary bladder papilloma Urinary bladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus - Cervix squamous cell carcinoma Uterus - Cervix

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium

observed - moderate

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus adenoma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus fibropapilloma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vagina papilloma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vulva squamous cell carcinoma Vulva

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

(Unspecified organ) tumor (Unspecified organ)

30

13

References: Storer JB, J Gerontol 1966 Jul;21(3):404-9