Strain Summary[not specified]-Gt(ROSA)26Sortm1(sb13)Tuv Krastm4Tyj Tg(Pdx1-cre)6Tuv TgTn(sb-T2/Onc)#Dla

Strain Name

[not specified]-Gt(ROSA)26Sortm1(sb13)Tuv Krastm4Tyj Tg(Pdx1-cre)6Tuv TgTn(sb-T2/Onc)#Dla

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

KrasLSL-G12D; Pdx1-cre; T2/Onc; Rosa26-LSL-SB13  •  KCTSB13

Description

Compound mutant mice. The genetic background of these mice was not specified but included at least some 129S4/SvJae, 129S6/SvEvTac, and FVB/N and possibly some other strain(s).

Strain Genetics

TgTn(sb-T2/Onc)#Dla
Gt(ROSA)26Sortm1(sb13)Tuv
Tg(Pdx1-cre)6Tuv

Models

7 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas adenocarcinoma - ductal Pancreas

very high

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70

Sites of Metastasis: Lung

1 pathology image(s)

Pancreas carcinoma Pancreas

64

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70

Sites of Metastasis: (Unspecified organ) , Liver , Lung

Pancreas neoplasm - cystic Pancreas

observed

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70

Pancreas neoplasm - cystic - papillary Pancreas

observed

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70

1 pathology image(s)

Pancreas pancreatic intraepithelial neoplasia (PanIN) - high grade Pancreas

observed

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70

Pancreas tumor Pancreas

high

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70

Pancreas tumor - pre-invasive Pancreas

36

References: Perez-Mancera PA, Nature 2012 Jun 14;486(7402):266-70