Strain Summary(C57BL/6 x 129/Sv)F1-Nf1tm1Tyj/+

Strain Name

(C57BL/6 x 129/Sv)F1-Nf1tm1Tyj/+

Strain Type(s)

hybrid  •  targeted mutation (knockout)

Strain Synonym(s)

Nf1+/-

Description

Heterozygous Nf1 mice on a hybrid background from a (C57BL/6 x 129/Sv)F1 cross with contribution from 129S2/SvPas.

Strain Genetics

Nf1tm1Tyj / Nf1+

Models

22 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

5.26

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Bone osteosarcoma Bone cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Erythrocyte hyperplasia Spleen

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Erythrocyte hyperplasia Spleen cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte - Myelocyte (Granulocyte) dysplasia Leukocyte - Myelocyte (Granulocyte)

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte - Myelocyte (Granulocyte) dysplasia Leukocyte - Myelocyte (Granulocyte) cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte)

13

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) cesium-137

19 - 40

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte leukemia - myelomonocytic Leukocyte

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Leukocyte lymphoma Leukocyte cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

PNS - Nerve sheath tumor - malignant PNS - Nerve sheath cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Pituitary gland adenoma Pituitary gland cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

Spleen hyperplasia Spleen

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) carcinoma (Unspecified organ)

5.26

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) squamous cell carcinoma (Unspecified organ) cesium-137

observed

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) tumor (Unspecified organ)

10.53

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) tumor (Unspecified organ) cesium-137

19.23 - 42.86

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) tumor - malignant (Unspecified organ)

13

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) tumor - malignant (Unspecified organ) cesium-137

19 - 40

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) tumor - solid (Unspecified organ)

8

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15

(Unspecified organ) tumor - solid (Unspecified organ) cesium-137

5 - 31

References: Nakamura JL, Cancer Res 2011 Jan 1;71(1):106-15