Strain Summary[not specified]-Blmtm3Brd Gt(ROSA)26Sortm1(sb11)Njen Ptentm1.1Jcad/+ TgTn(pb-sb-ITP)2mJcad

Strain Name

[not specified]-Blmtm3Brd Gt(ROSA)26Sortm1(sb11)Njen Ptentm1.1Jcad/+ TgTn(pb-sb-ITP)2mJcad

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  targeted mutation (other)  •  transgenic

Strain Synonym(s)

PtenSBm2/+; ITP2m; Rosa26SB11/+; Blmm3/m3  •  PISB

Description

Compound mutant mice. The genetic background of these mice was not specified but included at least 129S7/SvEvBrd-Hptrb-m2 and 129S7/SvEvBrd-Hptr+ and possibly some other strain(s).

Strain Genetics

TgTn(pb-sb-ITP)2mJcad
Ptentm1.1Jcad / Pten+
Gt(ROSA)26Sortm1(sb11)Njen
Gt(ROSA)26Sortm1(sb11)Njen
Ptentm1.1Jcad / Pten+
TgTn(pb-sb-ITP)2mJcad
TgTn(pb-sb-ITP)2mJcad

Models

19 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

67

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Intestine adenocarcinoma Intestine

2.3

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Intestine adenoma Intestine

24

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Intestine hyperplasia Intestine

3.5

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Intestine tumor Intestine

27

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte

observed

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Lung tumor Lung

observed

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Mammary gland carcinoma - adenosquamous Mammary gland

38

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Prostate gland adenocarcinoma Prostate gland

72

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Prostate gland hyperplasia Prostate gland

100

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

28

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Prostate gland tumor Prostate gland

100

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Skin keratoacanthoma Skin

73

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Thyroid gland tumor Thyroid gland

observed

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Uterus - Endometrium tumor Uterus - Endometrium

observed

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Uterus adenocarcinoma Uterus

12

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Uterus adenocarcinoma in situ Uterus

33

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Uterus hyperplasia Uterus

54

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741

Uterus tumor Uterus

46

References: de la Rosa J, Nat Genet 2017 May;49(5):730-741