Strain Summary[not specified]-Gt(ROSA)26Sortm2(sb11)Njen Speer6-ps1Tg(Alb-cre)21Mgn/? TgTn(sb-T2/Onc)68Dla

Strain Name

[not specified]-Gt(ROSA)26Sortm2(sb11)Njen Speer6-ps1Tg(Alb-cre)21Mgn/? TgTn(sb-T2/Onc)68Dla

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Alb-cre T2/Onc RLS  •  ATR  •  Alb-CreTg/WT; Rosa26-lsl-SB11Tg/WT; T2/OncTg/WT  •  SB-mutagenized

Description

Compound mutant mice. The genetic background of these mice was not specified but included at least some C57BL/6J, "129", FVB/N, and possibly some DBA and/or C57BL/6 (substrain unspecified).

Strain Genetics

TgTn(sb-T2/Onc)68Dla
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Speer6-ps1Tg(Alb-cre)21Mgn / Speer6-ps1?
Gt(ROSA)26Sortm2(sb11)Njen
Gt(ROSA)26Sortm2(sb11)Njen

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Liver - Bile duct cholangiocarcinoma Liver - Bile duct ethanol   ⋅   choline-deficient

0

References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588

Liver hepatocellular adenoma Liver ethanol   ⋅   choline-deficient

observed

References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588

Liver hepatocellular carcinoma Liver ethanol   ⋅   choline-deficient

observed

References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588

Liver tumor Liver ethanol   ⋅   choline-deficient

81

65

76

References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588

Liver tumor Liver nitisinone (NTBC)

40

78

References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588