Strain Summary[not specified]-Stk11tm1.1Rdp Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn

Strain Name

[not specified]-Stk11tm1.1Rdp Tg(Tyr-cre/ERT2)13Bos Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

Tp53L/L; Lkb1L/L

Description

Compound mutant mice. The genetic background was not specified but was ~50% C57BL/6 (described as "N1" onto that strain) and may have included some FVB, 129P2/OlaHsd, and 129S6/SvEvTac.

Strain Genetics

Tg(Tyr-cre/ERT2)13Bos
Tg(Tyr-cre/ERT2)13Bos
Tg(Tyr-cre/ERT2)13Bos

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Skin - Melanocyte melanoma Skin - Melanocyte 4-hydroxytamoxifen (4-OHT) (for inducing expression from mutant alleles)

0

References: Liu W, Cancer Cell 2012 Jun 12;21(6):751-64