Strain Summary[not specified]-Apctm2.1Cip/+ Lrig1tm1.1(cre/ERT2)Rjc/+

Strain Name

[not specified]-Apctm2.1Cip/+ Lrig1tm1.1(cre/ERT2)Rjc/+

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

Lrig1-CreERT2/+;Apcfl/+

Description

Heterozygous Lrig1tm1.1(cre/ERT2)Rjc, Apctm2.1Cip mice on an unspecified genetic background with possible contribution from 129S6/SvEvTac and 129P2/OlaHsd-Hprtb-m3.

Strain Genetics

Lrig1tm1.1(cre/ERT2)Rjc / Lrig1+
Lrig1tm1.1(cre/ERT2)Rjc / Lrig1+
Apctm2.1Cip / Apc+
Lrig1tm1.1(cre/ERT2)Rjc / Lrig1+

Models

26 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Eye - Retina lesion - epithelial Eye - Retina tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Gastrointestinal tract tumor Gastrointestinal tract tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Large Intestine - Colon - Distal tumor - luminal Intestine - Large Intestine - Colon - Distal tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal tamoxifen (For inducing expression from mutant alleles)

0

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Large Intestine - Colon adenoma - microadenoma Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Large Intestine - Colon lesion Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine - Duodenum - Periampullary region adenoma Intestine - Small Intestine - Duodenum - Periampullary region tamoxifen (For inducing expression from mutant alleles)

80

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine - Duodenum - Periampullary region tumor Intestine - Small Intestine - Duodenum - Periampullary region tamoxifen (For inducing expression from mutant alleles)

80

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine - Duodenum tumor Intestine - Small Intestine - Duodenum tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine - Ileum tumor Intestine - Small Intestine - Ileum tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine - Jejunum tumor Intestine - Small Intestine - Jejunum tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine lesion Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine - Small Intestine tumor Intestine - Small Intestine tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine dysplasia Intestine tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine lesion Intestine tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Intestine neoplasia Intestine tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Fundus dysplasia Stomach - Fundus tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Fundus hyperplasia - foveolar Stomach - Fundus tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Fundus lesion - dysplastic Stomach - Fundus tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Glandular - Pyloric antrum dysplasia - high grade Stomach - Glandular - Pyloric antrum tamoxifen (For inducing expression from mutant alleles)

observed - 100

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Glandular - Pyloric antrum hyperplasia Stomach - Glandular - Pyloric antrum tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Glandular - Pyloric antrum lesion - dysplastic Stomach - Glandular - Pyloric antrum tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Glandular - Pylorus dysplasia - high grade Stomach - Glandular - Pylorus tamoxifen (For inducing expression from mutant alleles)

100

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23

Stomach - Glandular - Pylorus lesion - dysplastic Stomach - Glandular - Pylorus tamoxifen (For inducing expression from mutant alleles)

observed

References: Powell AE, Am J Physiol Gastrointest Liver Physiol 2014 Jul 1;307(1):G16-23