Strain SummaryB6;129-Brca1tm2Mak Tg(Lck-cre)548Jxm Trp53tm1Brd

Strain Name

B6;129-Brca1tm2Mak Tg(Lck-cre)548Jxm Trp53tm1Brd

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

129;B6-Brca1tm2Mak Tg(Lck-cre)548Jxm Trp53tm1Brd  •  tBrca1-/-p53-/-

Description

Homozygous Trp53tm1Brd, Brca1tm2Mak mice also carrying the Tg(Lck-cre)548Jxm transgene on a mixed 129/J and C57BL/6 background with possible contributions from 129P2/OlaHsd, 129S7/SvEvBrd, and CBA.

Strain Genetics

Tg(Lck-cre)548Jxm

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte - Lymphocyte lymphoma Thymus

100

References: McPherson JP, Genes Dev 2004 May 15;18(10):1144-53

Leukocyte lymphoma Thymus

100

References: McPherson JP, Genes Dev 2004 May 15;18(10):1144-53