Strain SummaryC57BL/6-Gt(ROSA)26Sortm1(sb11)Njen Rag2tm1Fwa/+ TgTn(sb-T2/Onc3)#Njen

Strain Name

C57BL/6-Gt(ROSA)26Sortm1(sb11)Njen Rag2tm1Fwa/+ TgTn(sb-T2/Onc3)#Njen

Strain Type(s)

targeted mutation (knockout)  •  targeted mutation (other)  •  transgenic

Strain Synonym(s)

Rag2+/- (+SB)  •  Rag2 Het (+SB)  •  Rag2+/- with SB  •  SB-mutagenized Rag2+/-

Description

Compound mutant mice. The genetic background was predominantly C57BL/6 and may also include some C3H and/or some 129S/SvEv-Gpi1c and possibly some other strain(s).

Strain Genetics

TgTn(sb-T2/Onc3)#Njen
Gt(ROSA)26Sortm1(sb11)Njen
Rag2tm1Fwa / Rag2+
Gt(ROSA)26Sortm1(sb11)Njen
TgTn(sb-T2/Onc3)#Njen

Models

45 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue lipoma Adipose tissue

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Blood vessel hemangioma Blood vessel

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Blood vessel hemangiosarcoma Blood vessel

20

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

CNS - Brain - Astrocyte astrocytoma CNS - Brain - Astrocyte

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

CNS - Spinal cord tumor CNS - Spinal cord

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Eye - Harderian gland adenoma Eye - Harderian gland

3.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Gastrointestinal tract gastrointestinal intraepithelial neoplasia (GIN) Gastrointestinal tract

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Germ cell (sex not specified) tumor CNS - Brain

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Intestine - Small Intestine polyp Intestine - Small Intestine

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Intestine adenocarcinoma Intestine

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Intestine adenoma Intestine

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Leukocyte - Lymphocyte - B-lymphocyte lymphoma - splenic marginal zone Leukocyte - Lymphocyte - B-lymphocyte

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Leukocyte - Lymphocyte - T-lymphocyte leukemia Leukocyte - Lymphocyte - T-lymphocyte

observed

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Leukocyte leukemia Leukocyte

21

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Liver - Bile duct cholangioma Liver - Bile duct

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Liver foci Liver

4.2

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Liver hepatocellular adenoma Liver

30

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Liver hepatocellular carcinoma Liver

35

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Lung adenocarcinoma Lung

3.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Lung adenocarcinoma - papillary Lung

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Lung adenoma Lung

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Lung adenoma - papillary Lung

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Mammary gland adenocarcinoma Mammary gland

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Mammary gland adenoma Mammary gland

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Mammary gland carcinoma Mammary gland

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Mesodermal cell/mesoblast sarcoma Skin - Dermis

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Nose - Nasal cavity - Nasal gland adenoma Nose - Nasal cavity - Nasal gland

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Nose - Nasal cavity adenocarcinoma Nose - Nasal cavity

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Nose - Nasal cavity adenoma Nose - Nasal cavity

3.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Nose adenoma - papillary Nose

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Ovary luteoma Ovary

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Pancreas hyperplasia Pancreas

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

3.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Salivary gland adenoma Salivary gland

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Salivary gland carcinoma Salivary gland

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Skin - Hair follicle - Basal cell trichoepithelioma Skin - Hair follicle - Basal cell

1.0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Skin - Melanocyte melanocytoma Skin - Melanocyte

5.2

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Skin - Melanocyte melanoma - malignant Skin - Melanocyte

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Skin keratoacanthoma Skin

33

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Skin squamous cell carcinoma Skin

0

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Skin squamous cell papilloma Skin

3.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9

Stomach tumor - neuroendocrine Stomach

2.1

References: Rogers LM, J Immunol 2013 Apr 15;190(8):4393-9