Strain SummarySTOCK Apctm2Rak/+ Tg(KRT14-cre)8Brn

Strain Name

STOCK Apctm2Rak/+ Tg(KRT14-cre)8Brn

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

K14-cre; ApcCKO/+  •  K14-cre CKO/+

Description

Compound mutant mice. This STOCK genetic background was a mixture of FVB/N, C57BL/6 (including at least some C57BL/6J), "129/S" (including at least some "129/Sv"), and SJL.

Strain Genetics

Tg(KRT14-cre)8Brn
Apctm2Rak / Apc+

Models

12 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine tumor Intestine

0

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

5.9

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

Liver hepatoma Liver

5.9

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

Mammary gland adenocarcinoma Mammary gland

observed

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

Mammary gland metaplasia - squamous Mammary gland

observed

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

2 pathology image(s)

Mammary gland tumor Mammary gland

76.5

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

Sites of Metastasis: Lung

Mammary gland tumor - acinar Mammary gland

observed

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

3 pathology image(s)

Mammary gland tumor - basosquamous Mammary gland

observed

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

2 pathology image(s)

Mammary gland tumor - pilar Mammary gland

observed

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

2 pathology image(s)

Mammary gland tumor - undifferentiated Mammary gland

observed

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

2 pathology image(s)

Mesodermal cell/mesoblast myxosarcoma Mesodermal cell/mesoblast

5.9

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367

(Unspecified organ) tumor (Unspecified organ)

94.1

References: Kuraguchi M, PLoS Genet 2009 Feb;5(2):e1000367