Strain SummaryB6;C3H-Gt(ROSA)26Sortm1(sb11)Njen TgTn(sb-T2/Onc3)12740Njen

Strain Name

B6;C3H-Gt(ROSA)26Sortm1(sb11)Njen TgTn(sb-T2/Onc3)12740Njen

Strain Type(s)

targeted mutation (other)  •  transgenic

Strain Synonym(s)

T2/Onc3;RosaSBase

Description

Mice were generated on a C57BL/6J;C3H background and backcrossed to C57BL/6J. Mice contained the Gt(ROSA)26Sortm1(sb11)Njen mutation and also the TgTn(sb-T2/Onc3)12740Njen transgene.

Strain Genetics

Gt(ROSA)26Sortm1(sb11)Njen
Gt(ROSA)26Sortm1(sb11)Njen
TgTn(sb-T2/Onc3)12740Njen
TgTn(sb-T2/Onc3)12740Njen

Models

26 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Blood vessel hemangioma (Unspecified organ)

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Blood vessel hemangiosarcoma Blood vessel

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Sites of Metastasis: (Unspecified organ)

CNS - Brain - Astrocyte astrocytoma CNS - Brain - Astrocyte

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Clitoral gland squamous cell carcinoma Clitoral gland

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Liver adenoma Liver

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Liver hepatoblastoma Liver

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Liver hepatocellular carcinoma Liver

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Sites of Metastasis: Lung

Lung adenoma Lung

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Lung carcinoma Lung

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Mammary gland carcinoma Mammary gland

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Nose - Nasal cavity carcinoma Nose - Nasal cavity

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Ovary adenocarcinoma Ovary

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Parathyroid gland carcinoma Parathyroid gland

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Preputial/Clitoral gland (sex not specified) carcinoma Preputial/Clitoral gland (sex not specified)

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Salivary gland carcinoma Salivary gland

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Sites of Metastasis: (Unspecified organ)

Salivary gland squamous cell carcinoma Salivary gland

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Skin - Melanocyte melanoma Skin - Melanocyte

1.61

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

Sites of Metastasis: (Unspecified organ)

Skin squamous cell carcinoma Skin

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6

(Unspecified organ) adenoma (Unspecified organ)

observed

References: Dupuy AJ, Cancer Res 2009 Oct 15;69(20):8150-6