Strain SummaryB6;C3-Gt(ROSA)26Sortm1(sb11)Njen TgTn(sb-T2/Onc2)6070Njen

Strain Name

B6;C3-Gt(ROSA)26Sortm1(sb11)Njen TgTn(sb-T2/Onc2)6070Njen

Strain Type(s)

targeted mutation (other)  •  transgenic

Strain Synonym(s)

TG6070

Description

Mice were maintained on mostly a C57BL/6 genetic background which also contained some C3H. Mice carried the Gt(ROSA)26Sortm1(sb11)Njen (RosaSBase) mutation and also the TgTn(sb-T2/Onc2)6057Njen transgene.

Strain Genetics

TgTn(sb-T2/Onc2)6070Njen
Gt(ROSA)26Sortm1(sb11)Njen
TgTn(sb-T2/Onc2)6070Njen
Gt(ROSA)26Sortm1(sb11)Njen

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain medulloblastoma CNS - Brain

7.69

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum

15.38

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Intestine tumor Intestine

7.69

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte

15.38

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Leukocyte - Lymphocyte - Null (non-T, non-B) cell lymphoma Leukocyte - Lymphocyte - Null (non-T, non-B) cell

38.46

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Leukocyte - Lymphocyte - Null (non-T, non-B) cell lymphoma - disseminated Leukocyte - Lymphocyte - Null (non-T, non-B) cell

15.38

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte

61.54

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus

15.38

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6

(Unspecified organ) tumor (Unspecified organ)

100

References: Dupuy AJ, Nature 2005 Jul 14;436(7048):221-6