Strain Summary[not specified]-Apctm2Rfo/+ Smad4E6sad/+

Strain Name

[not specified]-Apctm2Rfo/+ Smad4E6sad/+

Strain Type(s)

spontaneous mutation  •  targeted mutation (knock-in)

Strain Synonym(s)

Apc+/1572T/Smad4+/Sad

Description

Double heterozygous mice. Both mutant alleles were on the same copy of chromosome 18 (cis). The genetic background of these mice was not specified but included some 129P2/OlaHsd.

Strain Genetics

Apctm2Rfo / Apc+
Smad4E6sad / Smad4+

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine adenoma Intestine

observed

References: Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547

2 pathology image(s)

Intestine tumor Intestine

60

100

References: Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547

Mammary gland adenocarcinoma Mammary gland

100

0

References: Gaspar C, PLoS Genet 2009 Jul;5(7):e1000547