Strain SummarySTOCK Parp1tm1Zqw Ptch1tm1Zim/+

Strain Name

STOCK Parp1tm1Zqw Ptch1tm1Zim/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Ptc1+/- PARP-1-/-  •  PARP-1-/-/Ptc1+/-

Description

Compound mutant mice. This STOCK genetic background included CD-1, C57BL/6, and "129/Sv" (including at least 129S2/SvPas).

Strain Genetics

Ptch1tm1Zim / Ptch1+

Models

14 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Cerebellum hyperplasia CNS - Brain - Cerebellum

71

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

CNS - Brain - Cerebellum hyperplasia CNS - Brain - Cerebellum X-radiation

75

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum

11

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum X-radiation

100

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Leukocyte lymphoma Leukocyte

22

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Leukocyte lymphoma Leukocyte X-radiation

12.5

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

44

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast X-radiation

0

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

0

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell X-radiation

19 - 54

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Skin - Epidermis - Basal cell preneoplastic lesion Skin - Epidermis - Basal cell

50

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Skin - Epidermis - Basal cell preneoplastic lesion Skin - Epidermis - Basal cell X-radiation

90

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

(Unspecified organ) tumor (Unspecified organ)

78

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

(Unspecified organ) tumor (Unspecified organ) X-radiation

100

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9