Strain SummarySTOCK Parp1tm1Zqw/+ Ptch1tm1Zim/+

Strain Name

STOCK Parp1tm1Zqw/+ Ptch1tm1Zim/+

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Ptc1+/- PARP-1+/-  •  PARP-1+/-/Ptc1+/-

Description

Double heterozygous mice. This STOCK genetic background included CD-1, C57BL/6, and "129/Sv" (including at least 129S2/SvPas).

Strain Genetics

Parp1tm1Zqw / Parp1+
Ptch1tm1Zim / Ptch1+

Models

5 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain - Cerebellum medulloblastoma CNS - Brain - Cerebellum X-radiation

90

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Leukocyte lymphoma Leukocyte X-radiation

4.8

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast X-radiation

9.5

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell X-radiation

0

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9

(Unspecified organ) tumor (Unspecified organ) X-radiation

93

References: Tanori M, Carcinogenesis 2008 Oct;29(10):1911-9