Strain SummaryFVB;129P2-Cdh1tm1Jjon/+ Tg(KRT14-cre)8Brn Trp53tm1Brn

Strain Name

FVB;129P2-Cdh1tm1Jjon/+ Tg(KRT14-cre)8Brn Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

K14cre;Cdh1F/+p53F/F

Description

Mice were homozygous for Trp53tm1Brn, heterozygous for Cdh1tm1Jjon, and also had the Tg(KRT14-cre)8Brn transgene. Mice were on a mixed FVB/N, 129P2/OlaHsd genetic background.

Strain Genetics

Cdh1tm1Jjon / Cdh1+

Models

11 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland adenocarcinoma Mammary gland

observed - 38.46

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49   ⋅   Jonkers J, MGI Direct Data Submission 2009;():

10 pathology image(s)

Mammary gland carcinoma - lobular Mammary gland

0

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Mammary gland carcinoma - solid Mammary gland

observed - 26.92

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49   ⋅   Jonkers J, MGI Direct Data Submission 2009;():

7 pathology image(s)

Mammary gland carcinoma in situ Mammary gland

7.69

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Mammary gland carcinosarcoma Mammary gland

observed - 38.46

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49   ⋅   Jonkers J, MGI Direct Data Submission 2009;():

8 pathology image(s)

Mammary gland tumor Mammary gland

73.08

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Sites of Metastasis: Lung , Lymph node

Salivary gland tumor Salivary gland

0

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Skin pilomatrixoma Skin

observed

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Skin squamous cell carcinoma Skin

observed

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Thymus thymoma Thymus

3.85

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49

Uterus - Endometrium tumor Uterus - Endometrium

0

References: Derksen PW, Cancer Cell 2006 Nov;10(5):437-49