Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets
Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology
Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice
Send Questions and
Comments to User Support.
Last Database Update
2019-12-08
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
  
Strain
KK/HlJ
Strain Synonyms KK/HiJ  •  KK/J
Strain Note: Inbred strain. This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background results in progressive hearing loss with onset after 10 months of age.
Strain Tumor Overview Expanded View
Tumors 152 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records		 Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous) 2 0
Adipose tissue lipoma Abdominal cavity None (spontaneous) 15 0 - 50
Adipose tissue lipoma Peritoneal cavity None (spontaneous) 2 0
Adipose tissue lipoma - pedunculated Pancreas None (spontaneous) 1 observed
Adipose tissue lipoma - pedunculated Abdominal cavity None (spontaneous) 1 observed
Adipose tissue lipoma - pedunculated Abdominal wall None (spontaneous) 1 observed
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous) 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 2 0 - low
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 2 0
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous) 2 0 - moderate
Adrenal gland adenoma Adrenal gland None (spontaneous) 15 0 - 14.29
Adrenal gland hyperplasia Adrenal gland None (spontaneous) 15 0 - 28.57
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous) 2 0
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous) 1 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous) 2 0
Blood vessel hemangioma Blood vessel None (spontaneous) 2 0
Blood vessel hemangioma Uterus None (spontaneous) 1 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 2 0
Blood vessel hemangiosarcoma Liver None (spontaneous) 2 0
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Bone - Femur hyperplasia Bone - Femur None (spontaneous) 1 observed
Bone - Femur lesion - fibro-osseous Bone - Femur None (spontaneous) 4 observed
Bone - Humerus hyperplasia Bone - Humerus None (spontaneous) 1 observed
Bone - Humerus lesion - fibro-osseous Bone - Humerus None (spontaneous) 1 observed
Bone - Patella hyperplasia Bone - Patella None (spontaneous) 1 observed
Bone - Skull hyperplasia Bone - Skull None (spontaneous) 1 observed
Bone - Skull lesion - fibro-osseous Bone - Skull None (spontaneous) 1 observed
Bone - Vertebral column - Vertebra lesion - fibro-osseous Bone - Vertebral column - Vertebra None (spontaneous) 1 observed
Bone hyperplasia Bone None (spontaneous) 5 0 - observed
Bone hyperplasia Leg None (spontaneous) 1 observed
Bone lesion Bone None (spontaneous) 3 observed
Bone lesion - fibro-osseous Bone None (spontaneous) 26 0 - 100
Ear - Middle ear polyp Ear - Middle ear None (spontaneous) 1 observed
Epididymis cyst Epididymis None (spontaneous) 1 0
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous) 2 0
Erythrocyte neoplasm Erythrocyte None (spontaneous) 2 0
Esophagus hyperplasia Esophagus None (spontaneous) 2 0
Eye - Harderian gland adenoma Eye - Harderian gland None (spontaneous) 1 observed
Eye - Lacrimal gland hyperplasia Eye - Lacrimal gland None (spontaneous) 15 0 - 28.57
Eye adenoma Eye None (spontaneous) 15 0 - 6.67
Eye hyperplasia Eye None (spontaneous) 15 0 - 71.43
Forestomach hyperplasia - papillary Forestomach None (spontaneous) 2 0
Forestomach papilloma Forestomach None (spontaneous) 2 0
Gallbladder cyst Gallbladder None (spontaneous) 17 0 - 11.11
Gallbladder hyperplasia Gallbladder None (spontaneous) 2 0
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous) 2 0
Intestine - Large Intestine - Cecum adenoma Intestine - Large Intestine - Cecum None (spontaneous) 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous) 17 0 - low
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous) 2 0 - low
Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon None (spontaneous) 16 0 - 14.29
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous) 18 0 - 16.67
Kidney adenoma Kidney None (spontaneous) 2 0
Leukocyte - Lymphocyte - B-lymphocyte - Immature plasma cell plasmacytoma Lymph node None (spontaneous) 1 2.86
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell plasmacytoma Lymph node - Cervical None (spontaneous) 15 0 - 14.29
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell plasmacytoma Lymph node None (spontaneous) 14 0 - 14.29
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell None (spontaneous) 2 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous) 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous) 2 0
Leukocyte lymphoma Lymph node - Cervical None (spontaneous) 15 0 - 14.29
Leukocyte lymphoma Leukocyte None (spontaneous) 17 0 - 33.33
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous) 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous) 2 0
Liver hepatoma Liver None (spontaneous) 2 0 - low
Liver tumor Liver None (spontaneous) 12 0 - 14.29
Lung adenoma Lung None (spontaneous) 21 0 - 16.67
Lung hyperplasia Lung None (spontaneous) 2 0
Lymph node - Cervical cyst Lymph node - Cervical None (spontaneous) 15 0 - 42.86
Lymph node cyst Lymph node None (spontaneous) 17 0 - low
Lymph node hyperplasia Lymph node None (spontaneous) 15 0 - 28.57
Lymph node hyperplasia Reticulocyte None (spontaneous) 2 0 - moderate
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous) 17 0 - low
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous) 6 0 - low
Mesodermal cell/mesoblast sarcoma Muscle - Striated - Skeletal None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous) 1 0
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous) 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous) 1 0
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 2 0
Muscle - Striated - Skeletal hyperplasia Muscle - Striated - Skeletal None (spontaneous) 14 0 - 14.29
Muscle - Striated - Skeletal hyperplasia - acinar Muscle - Striated - Skeletal None (spontaneous) 1 0
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous) 1 0
Myoepithelial cell myoepithelioma Lung None (spontaneous) 2 0
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous) 2 0
Nail squamous cell carcinoma Nail None (spontaneous) 2 0
Ovary - Follicle cyst Ovary - Follicle None (spontaneous) 1 observed
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous) 1 high
Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell None (spontaneous) 1 0
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous) 6 0 - 11.11
Ovary adenoma Ovary None (spontaneous) 1 0
Ovary cyst Ovary None (spontaneous) 6 0 - 71.43
Ovary cyst - bursal Ovary None (spontaneous) 1 low
Ovary hyperplasia - epithelial Ovary None (spontaneous) 1 0
Ovary tumor - tubulostromal Ovary None (spontaneous) 1 0
PNS - Nerve sheath tumor Skin None (spontaneous) 17 0 - 33.33
PNS - Nerve sheath tumor Ear None (spontaneous) 2 0
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous) 2 0
Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans None (spontaneous) 2 observed
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous) 8 observed
Pancreas hyperplasia Pancreas None (spontaneous) 15 25 - 100
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous) 1 0
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous) 18 0 - low
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous) 2 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous) 2 0
Skin dysplasia Skin None (spontaneous) 15 0 - 12.5
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous) 2 0
Skin hyperplasia - epithelial Ear None (spontaneous) 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous) 2 0
Spleen hyperplasia Spleen None (spontaneous) 16 0 - 75
Stomach - Epithelium cyst - squamous Stomach - Epithelium None (spontaneous) 1 observed
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous) 3 0 - low
Stomach - Glandular cyst Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous) 4 0 - low
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous) 2 0 - low
Stomach - Glandular polyp Stomach - Glandular None (spontaneous) 2 0
Stomach adenoma Stomach None (spontaneous) 15 0 - 25
Stomach hyperplasia Stomach None (spontaneous) 15 0 - 14.29
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 low
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis hyperplasia Testis None (spontaneous) 5 0 - 14.29
Thyroid gland cyst Thyroid gland None (spontaneous) 16 0 - 14.29
Thyroid gland hyperplasia Thyroid gland None (spontaneous) 16 0 - 28.57
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous) 7 observed - high
Tooth hyperplasia Tooth None (spontaneous) 15 0 - 33.33
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous) 2 0
Ureter hyperplasia Muscle - Smooth None (spontaneous) 2 0
Ureter polyp Ureter None (spontaneous) 2 0
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous) 2 0
Urinary bladder papilloma Urinary bladder None (spontaneous) 2 0
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous) 6 0 - observed
Uterus adenoma Uterus None (spontaneous) 1 0
Uterus cyst Uterus None (spontaneous) 5 0 - 50
Uterus fibropapilloma Uterus None (spontaneous) 1 0
Vagina papilloma Vagina None (spontaneous) 1 0
Vulva squamous cell carcinoma Vulva None (spontaneous) 1 0
Other Database Links
Additional information about these mice:
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/KK.shtml
JAX Mice http://jaxmice.jax.org/strain/002106.html