Strain SummaryB6;129-Trp53tm1Brd Xpctm1Ecf

Strain Name

B6;129-Trp53tm1Brd Xpctm1Ecf

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

XPC-/- Trp53-/-

Description

These mice were homozygous for both mutant alleles. The genetic background of these mice was stated to be 75% "129/Sv" (including 129S7/SvEvBrd-Hprt+) and 25% C57BL/6.

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Testis - Germ cell teratocarcinoma Testis - Germ cell

observed

References: Cheo DL, Cancer Res 1999 Feb 15;59(4):771-5

Testis tumor Testis

54

References: Cheo DL, Cancer Res 1999 Feb 15;59(4):771-5

(Unspecified organ) tumor (Unspecified organ)

100

100

100

References: Cheo DL, Cancer Res 1999 Feb 15;59(4):771-5