Strain SummaryB6;129-B2mtm1Unc Il2tm1Hor

Strain Name

B6;129-B2mtm1Unc Il2tm1Hor

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

B2m-/- x IL2-/-  •  β2mnull x IL-2null  •  IL-2null X β2mnull  •  IL-2NULL X β2MNULL  •  interleukin 2- and β2-microglobulin-deficient

Description

Mice were homozygous for both B2mtm1Unc and Il2tm1Hor. The genetic background of these mice is a mixture of C57BL/6, 129P2/OlaHsd, and some other unspecified substrain of "129/Sv".

Models

9 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon

0 - 40

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7   ⋅   Shah SA, Inflamm Bowel Dis 1998 Aug;4(3):196-202   ⋅   Sohn KJ, Cancer Res 2001 Sep 15;61(18):6912-7

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon folate-deficient

20

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon folate-supplemented

32

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon carcinoma in situ Intestine - Large Intestine - Colon folate-deficient

13

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon carcinoma in situ Intestine - Large Intestine - Colon

26

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon carcinoma in situ Intestine - Large Intestine - Colon folate-supplemented

2.9

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon folate-deficient

23

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon

9.3

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon folate-supplemented

21

References: Carrier J, Cancer Epidemiol Biomarkers Prev 2003 Nov;12(11 Pt 1):1262-7