Strain SummaryC57BL/6J-ApcMin/+

Strain Name

C57BL/6J-ApcMin/+

Strain Type(s)

chemically induced mutation

Strain Synonym(s)

Apc/Min  •  Apcmin  •  B6-Apc+/ApcMin  •  B6 ApcMin/Apc+  •  B6-ApcMin/Apc+  •  B6-Apc+/ApcMin  •  B6 Min/+  •  B6-Min/+  •  B6.Min/+  •  B6 Min  •  B6-Min  •  B6-Min (ApcMin/Apc+)  •  C57BL/6-ApcMin/+  •  C57BL/6-Min/+  •  C57BL/6J-ApcMin/+Apc  •  C57BL/6J-ApcMin/+  •  C57BL/6J-ApcMin  •  C57BL/6 J-Min/+  •  C57BL/6J Min/+  •  C57BL/6J-Min/+  •  C57BL/6J.Min/+  •  C57BL/6J(Min/+)  •  C57BL/6j Min  •  C57BL/6J Min  •  Apc+/-  •  Apc mutant Min  •  ApcMin/+  •  ApcMin  •  ApcMin/+  •  ApcMIN  •  Apc+/-  •  Apc+/ApcMin  •  ApcMin/Apc+  •  ApcMin  •  APCMin  •  ApcMin/Apc+  •  Apc+/ApcMin  •  ICRF MIN  •  Min  •  Min/+  •  Min  •  MIN  •  multiple intestinal neoplasia  •  multiple intestinal neoplasia/+

Description

Heterozygous mice - "Min" mutation. Background is C57BL/6J.

Strain Genetics

ApcMin / Apc+

Models

124 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast desmoid Skin

15

References: Smits R, Gastroenterology 1998 Feb;114(2):275-83

Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal

observed

References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26

Intestine - Large Intestine - Colon - Proximal adenoma Intestine - Large Intestine - Colon - Proximal

observed

References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

observed - 52

observed - 52

observed

observed - 91

References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66   ⋅   Dove WF, Cancer Res 1997 Mar 1;57(5):812-4   ⋅   Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5   ⋅   Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4   ⋅   Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8   ⋅   Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52   ⋅   Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Moser AR, Science 1990 Jan 19;247(4940):322-4   ⋅   Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon celecoxib

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon folate-deficient

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon folate-supplemented

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

observed

References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)

38

100

observed

References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

50

92

observed

References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66

Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon troglitazone

observed

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Large Intestine - Colon carcinoma Intestine - Large Intestine - Colon

observed

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Large Intestine - Colon dysplasia Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5

Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon folate-deficient

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon

0 - observed

0 - observed

observed

References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5   ⋅   Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon folate-supplemented

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Large Intestine - Colon foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

observed

References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5

Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

References: Erik Paulsen J, Cancer Res 2001 Jul 1;61(13):5010-5

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon low vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Large Intestine - Colon polyp Intestine - Large Intestine - Colon high vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon troglitazone

observed

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon

32

47 - 52

observed - 30

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53   ⋅   Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40   ⋅   Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82   ⋅   Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon sulindac

observed

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

50 - 71

80 - 100

57

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53   ⋅   Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40   ⋅   Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)   ⋅   retinoic acid (RA)

58

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon retinoic acid (RA)

53 - 80

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53

Intestine - Large Intestine adenoma Intestine - Large Intestine

observed

References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6

Intestine - Large Intestine polyp Intestine - Large Intestine

observed

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6   ⋅   Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Intestine - Large Intestine polyp Intestine - Large Intestine increased fat, decreased fiber

observed

References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Intestine - Large Intestine polyp Intestine - Large Intestine high fat

observed

References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Intestine - Large Intestine polyp Intestine - Large Intestine vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Large Intestine polyp Intestine - Large Intestine vitamin D3 (1alpha,25-(OH)2-D3) (VD3)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Large Intestine polyp Intestine - Large Intestine sulindac

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Distal adenoma Intestine - Small Intestine - Distal

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Distal adenoma Intestine - Small Intestine - Distal celecoxib

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Distal adenoma Intestine - Small Intestine - Distal piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Distal polyp Intestine - Small Intestine - Distal vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Distal polyp Intestine - Small Intestine - Distal vitamin D3 (1alpha,25-(OH)2-D3) (VD3)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Distal polyp Intestine - Small Intestine - Distal sulindac

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Distal polyp Intestine - Small Intestine - Distal

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15   ⋅   Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Distal polyp Intestine - Small Intestine - Distal low vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine - Distal polyp Intestine - Small Intestine - Distal high vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal piroxicam   ⋅   difluoromethylornithine (DFMO)

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Distal tumor Intestine - Small Intestine - Distal difluoromethylornithine (DFMO)

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

observed - 99

References: Dove WF, Cancer Res 1997 Mar 1;57(5):812-4   ⋅   Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52   ⋅   Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Moser AR, Science 1990 Jan 19;247(4940):322-4   ⋅   Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum folate-deficient

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum folate-supplemented

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Duodenum neoplasia Intestine - Small Intestine - Duodenum

observed

References: Sundberg J, Personal Communication 1997;():

1 pathology image(s)

Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum

observed

References: Sundberg J, Personal Communication 1997;():

1 pathology image(s)

Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum

observed - 97

References: Dove WF, Cancer Res 1997 Mar 1;57(5):812-4   ⋅   Klein IK, Cancer Res 2000 Apr 15;60(8):2077-80   ⋅   Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52   ⋅   Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Moser AR, Science 1990 Jan 19;247(4940):322-4   ⋅   Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum folate-deficient

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum folate-supplemented

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum

observed

References: Dove WF, Cancer Res 1997 Mar 1;57(5):812-4   ⋅   Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8   ⋅   Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52   ⋅   Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum folate-deficient

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum folate-supplemented

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine - Jejunum neoplasia Intestine - Small Intestine - Jejunum

observed

References: Sundberg J, Personal Communication 1997;():

1 pathology image(s)

Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum

observed

References: Sundberg J, Personal Communication 1997;():

1 pathology image(s)

Intestine - Small Intestine - Medial adenoma Intestine - Small Intestine - Medial

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Medial adenoma Intestine - Small Intestine - Medial celecoxib

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Medial adenoma Intestine - Small Intestine - Medial piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Medial polyp Intestine - Small Intestine - Medial vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Medial polyp Intestine - Small Intestine - Medial vitamin D3 (1alpha,25-(OH)2-D3) (VD3)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Medial polyp Intestine - Small Intestine - Medial sulindac

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Medial polyp Intestine - Small Intestine - Medial

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15   ⋅   Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Medial polyp Intestine - Small Intestine - Medial low vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine - Medial polyp Intestine - Small Intestine - Medial high vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine - Medial tumor Intestine - Small Intestine - Medial

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Medial tumor Intestine - Small Intestine - Medial piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Medial tumor Intestine - Small Intestine - Medial piroxicam   ⋅   difluoromethylornithine (DFMO)

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Medial tumor Intestine - Small Intestine - Medial difluoromethylornithine (DFMO)

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Proximal adenoma Intestine - Small Intestine - Proximal

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Proximal adenoma Intestine - Small Intestine - Proximal celecoxib

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Proximal adenoma Intestine - Small Intestine - Proximal piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal vitamin D3 (1alpha,25-(OH)2-D3) (VD3)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal sulindac

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15   ⋅   Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal low vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine - Proximal polyp Intestine - Small Intestine - Proximal high vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal piroxicam   ⋅   difluoromethylornithine (DFMO)

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine - Proximal tumor Intestine - Small Intestine - Proximal difluoromethylornithine (DFMO)

observed

References: Jacoby RF, Cancer Res 2000 Apr 1;60(7):1864-70

Intestine - Small Intestine adenoma Intestine - Small Intestine

100

100

observed

observed

References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66   ⋅   Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Reitmair AH, Cancer Res 1996 Jul 1;56(13):2922-6   ⋅   Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine adenoma Intestine - Small Intestine folate-deficient

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine adenoma Intestine - Small Intestine folate-supplemented

observed

References: Song J, Cancer Res 2000 Oct 1;60(19):5434-40

Intestine - Small Intestine adenoma Intestine - Small Intestine 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)

100

100

observed

References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66

Intestine - Small Intestine adenoma Intestine - Small Intestine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

100

100

observed

References: Andreassen A, Mutat Res 2002 May 27;517(1-2):157-66

Intestine - Small Intestine neoplasia Intestine - Small Intestine

observed

References: Sundberg J, Personal Communication 1997;():

5 pathology image(s)

Intestine - Small Intestine polyp Intestine - Small Intestine

observed

observed

observed

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15   ⋅   Saez E, Nat Med 1998 Sep;4(9):1058-61   ⋅   Sundberg J, Personal Communication 1997;():   ⋅   Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

5 pathology image(s)

Intestine - Small Intestine polyp Intestine - Small Intestine increased fat, decreased fiber

observed

References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Intestine - Small Intestine polyp Intestine - Small Intestine high fat

observed

References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Intestine - Small Intestine polyp Intestine - Small Intestine troglitazone

observed

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Small Intestine polyp Intestine - Small Intestine low vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine polyp Intestine - Small Intestine high vitamin

observed

References: Bashir O, Carcinogenesis 2004 Aug;25(8):1507-15

Intestine - Small Intestine tumor Intestine - Small Intestine sulindac

observed

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Small Intestine tumor Intestine - Small Intestine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

100

100

observed - 100

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53   ⋅   Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40   ⋅   Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82

Intestine - Small Intestine tumor Intestine - Small Intestine

100

observed - 100

100

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53   ⋅   Mollersen L, Mutat Res 2004 Jan 10;557(1):29-40   ⋅   Paulsen JE, Carcinogenesis 1999 Jul;20(7):1277-82

Intestine - Small Intestine tumor Intestine - Small Intestine 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)   ⋅   retinoic acid (RA)

100

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53

Intestine - Small Intestine tumor Intestine - Small Intestine retinoic acid (RA)

100

References: Mollersen L, Carcinogenesis 2004 Jan;25(1):149-53

Intestine adenocarcinoma Intestine

0

References: Moser AR, J Cell Biol 1992 Mar;116(6):1517-26

Intestine adenoma Intestine

observed

observed - 100

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4   ⋅   Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8   ⋅   Luongo C, Cancer Res 1994 Nov 15;54(22):5947-52   ⋅   Luongo C, Genes Chromosomes Cancer 1996 Nov;17(3):194-8   ⋅   Moser AR, J Cell Biol 1992 Mar;116(6):1517-26   ⋅   Shoemaker AR, Oncogene 2000 May 25;19(23):2774-9   ⋅   Su LK, Science 1992 May 1;256(5057):668-70

Intestine adenoma Intestine gamma-radiation

100

References: Luongo C, Genes Chromosomes Cancer 1996 Nov;17(3):194-8

Intestine adenoma Intestine celecoxib

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine adenoma Intestine piroxicam

observed

References: Jacoby RF, Cancer Res 2000 Sep 15;60(18):5040-4

Intestine dysplasia Intestine

observed

References: Levy DB, Cancer Res 1994 Nov 15;54(22):5953-8

Intestine neoplasia Intestine

observed

References: Sundberg J, Personal Communication 1997;():

7 pathology image(s)

Intestine polyp Intestine vitamin D3 analogue (1alpha,25-(OH)2-16-ene-19-nor-24-oxo D3) (Ro 26-9114)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine polyp Intestine vitamin D3 (1alpha,25-(OH)2-D3) (VD3)

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine polyp Intestine sulindac

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6

Intestine polyp Intestine

observed

observed

References: Huerta S, Cancer Res 2002 Feb 1;62(3):741-6   ⋅   Sundberg J, Personal Communication 1997;():

7 pathology image(s)

Intestine tumor Intestine N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

100

very high

References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5   ⋅   Shoemaker AR, Cancer Res 1997 May 15;57(10):1999-2006

Mammary gland carcinoma Mammary gland

observed

References: Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81

Mammary gland carcinoma Mammary gland N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0 - 37.5

References: Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81

Mammary gland lesion Mammary gland N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

38

References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5

Mammary gland tumor Mammary gland

0 - 41

References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5   ⋅   Moser AR, Proc Natl Acad Sci U S A 1993 Oct 1;90(19):8977-81   ⋅   Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Mammary gland tumor Mammary gland increased fat, decreased fiber

20

References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Mammary gland tumor Mammary gland high fat

26

References: Wasan HS, Proc Natl Acad Sci U S A 1997 Apr 1;94(7):3308-13

Mammary gland tumor Mammary gland N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

93

References: Moser AR, Cancer Res 2001 Apr 15;61(8):3480-5

Skin gland - Sebaceous gland cyst Skin gland - Sebaceous gland

92

References: Smits R, Gastroenterology 1998 Feb;114(2):275-83