Strain SummaryC57BL/6JIco

Strain Name

C57BL/6JIco

Strain Type(s)

inbred

Strain Synonym(s)

C57BL/6  •  C57Bl/6J  •  C57BL/6J  •  C57BL/6J Ico  •  Wild type  •  Wild-type  •  wild-type C57BL/6  •  Wild-type C57BL/6J  •  WT

Models

101 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue lipoma Abdominal cavity

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Adipose tissue lipoma CNS - Brain

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Adipose tissue lipoma CNS - Brain estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

0

0.8

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla diethylstilbestrol (DES)

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell

100

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell diethylstilbestrol (DES)

100

87

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Blood vessel hemangiosarcoma Blood vessel

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Bone lesion Bone - Sternum

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Bone lesion Bone - Femur

13

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Bone lesion Bone - Sternum diethylstilbestrol (DES)

27

13

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Bone lesion Bone - Femur diethylstilbestrol (DES)

100

87

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Bone lesion - fibro-osseous Bone

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Bone lesion - fibro-osseous Bone estradiol (E2)

93.3

66.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Bone osteosarcoma Bone

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Bone osteosarcoma Bone diethylstilbestrol (DES)

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Bone osteosarcoma Bone estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

CNS - Brain - Cerebrum glioma CNS - Brain - Cerebrum

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

CNS - Brain - Cerebrum glioma CNS - Brain - Cerebrum diethylstilbestrol (DES)

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

CNS - Brain glioma CNS - Brain

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

CNS - Brain glioma CNS - Brain diethylstilbestrol (DES)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Connective tissue - Fibroblast fibrosarcoma Uterus - Cervix diethylstilbestrol (DES)

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Connective tissue - Fibroblast fibrosarcoma Skin

0.8

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Forestomach tumor Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)

6.7

6.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Gallbladder papilloma Gallbladder 2-acetamidofluorene (2-AAF)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine

0

6.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine WY-14,643

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Intestine - Small Intestine tumor Intestine - Small Intestine

0

observed - 1.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Intestine tumor Intestine benzo[a]pyrene (BP) (BaP) (B[a]P)

0

40

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Kidney hyperplasia Kidney phenacetin

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Kidney transitional cell carcinoma Kidney p-cresidine

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Kidney tumor Kidney phenacetin

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte diethylstilbestrol (DES)

0

6.7

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver

13

References: Lacroix-Triki M, Toxicol Pathol 2003 May-Jun;31(3):304-9

18 pathology image(s)

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen

6.5

References: Lacroix-Triki M, Toxicol Pathol 2003 May-Jun;31(3):304-9

3 pathology image(s)

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Uterus

1.5

References: Lacroix-Triki M, Toxicol Pathol 2003 May-Jun;31(3):304-9

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0.8 - 13

0

References: Lacroix-Triki M, Toxicol Pathol 2003 May-Jun;31(3):304-9   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Sites of Metastasis: Bone marrow , Kidney , Lung , Lymph node

11 pathology image(s)

Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte - Myelocyte (Granulocyte) leukemia - myelocytic Leukocyte - Myelocyte (Granulocyte) estradiol (E2)

0

6.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte - Myelocyte (Granulocyte) sarcoma - myeloid Leukocyte - Myelocyte (Granulocyte)

0.8

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte lymphoma Leukocyte

0 - 2.5

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte lymphoma Leukocyte benzo[a]pyrene (BP) (BaP) (B[a]P)

13.3

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte lymphoma Leukocyte Cyclosporin A

0 - 21.4

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte lymphoma Leukocyte diethylstilbestrol (DES)

0

6.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte lymphoma Leukocyte estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Leukocyte lymphoma Leukocyte WY-14,643

0

6.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver - Oval cell hyperplasia Liver - Oval cell

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver - Oval cell hyperplasia Liver - Oval cell WY-14,643

46.7

40

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver adenoma Liver

0

0 - observed

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver hepatocellular adenoma Liver

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver hepatocellular adenoma Liver WY-14,643

6.7

13.3

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver hepatocellular carcinoma Liver

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver hepatocellular carcinoma Liver estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver hepatocellular carcinoma Liver WY-14,643

6.7

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver tumor Liver p-cresidine

10

0 - 33.3

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Liver tumor Liver 2-acetamidofluorene (2-AAF)

10

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Lung adenoma Lung

0

2.5 - 6.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Lung adenoma Lung estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mammary gland adenocarcinoma Mammary gland

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mammary gland adenocarcinoma Mammary gland diethylstilbestrol (DES)

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mammary gland hyperplasia - focal Mammary gland

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Mammary gland hyperplasia - focal Mammary gland diethylstilbestrol (DES)

67

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Mesodermal cell/mesoblast sarcoma CNS - Brain

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mesodermal cell/mesoblast sarcoma Abdominal cavity

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mesodermal cell/mesoblast sarcoma Skin

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mesodermal cell/mesoblast sarcoma Skin estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mesodermal cell/mesoblast sarcoma CNS - Brain estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Mesodermal cell/mesoblast sarcoma Abdominal cavity estradiol (E2)

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Muscle - Smooth leiomyosarcoma Muscle - Smooth

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Ovary - Germ cell teratoma CNS - Brain

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Ovary - Germ cell teratoma CNS - Brain estradiol (E2)

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Ovary - Granulosa cell tumor Ovary - Granulosa cell

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Ovary adenoma - tubulostromal Ovary

0.8

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis diethylstilbestrol (DES)

80

87

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia diethylstilbestrol (DES)

47

67

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Pituitary gland adenoma Pituitary gland

0

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Pituitary gland adenoma Pituitary gland diethylstilbestrol (DES)

13 - 13.3

13 - 13.3

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Placenta - Decidua deciduoma Placenta - Decidua

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Prostate gland - Anterior lobe metaplasia - squamous Prostate gland - Anterior lobe

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Prostate gland - Anterior lobe metaplasia - squamous Prostate gland - Anterior lobe diethylstilbestrol (DES)

87

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Testis - Germ cell teratoma CNS - Brain

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Testis - Germ cell teratoma CNS - Brain estradiol (E2)

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell)

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) diethylstilbestrol (DES)

6.7

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20   ⋅   van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

0

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) diethylstilbestrol (DES)

53

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

Thymus thymoma Thymus

0

0

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Thyroid gland - Follicular cell adenoma Thyroid gland - Follicular cell

0

0.8

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Urinary bladder tumor Urinary bladder p-cresidine

0

0 - 13.3

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Urinary bladder tumor Urinary bladder 2-acetamidofluorene (2-AAF)

0

20

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

Uterus - Uterine gland hyperplasia Uterus - Uterine gland diethylstilbestrol (DES)

observed

References: McAnulty PA, Toxicol Pathol 2005;33(5):609-20

(Unspecified organ) tumor (Unspecified organ)

0 - 5.9

0 - 5.9

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

(Unspecified organ) tumor (Unspecified organ) benzo[a]pyrene (BP) (BaP) (B[a]P)

20

46.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

(Unspecified organ) tumor (Unspecified organ) p-cresidine

10

0 - 46.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

(Unspecified organ) tumor (Unspecified organ) 2-acetamidofluorene (2-AAF)

10

20

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27

(Unspecified organ) tumor (Unspecified organ) diethylstilbestrol (DES)

13.3

26.7

References: van Kreijl CF, Toxicol Pathol 2001;29 Suppl():117-27