Strain SummarySTOCK Tg(Ela1-Tgfa)150Bri Trp53tm1Tyj/+

Strain Name

STOCK Tg(Ela1-Tgfa)150Bri Trp53tm1Tyj/+

Strain Type(s)

targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

EL-TGF-α-hGH (line #2261-3) p53+/-  •  TGF-α/p53+/-  •  TGFα/p53+/-  •  TGF-α p53+/-  •  TGF-α/p53+/-  •  TGFα/p53+/-

Description

Mice carried the Tg(Ela1-Tgfa)150Bri transgene and were heterozygous for the Trp53tm1Tyj allele. The genetic background of these mice was predominantly a mixture of C57BL/6 and BALB/c with some SJL and/or 129S2/SvPas also possibly involved.

Strain Genetics

Trp53tm1Tyj / Trp53+
Tg(Ela1-Tgfa)150Bri

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

3.3

References: Wagner M, Genes Dev 2001 Feb 1;15(3):286-93

Pancreas tumor Pancreas

observed - 73

References: Seitz U, Cancer Res 2001 May 15;61(10):3853-7   ⋅   Wagner M, Genes Dev 2001 Feb 1;15(3):286-93