Strain SummaryB6;129P2-Msh2tm1Rak

Strain Name

B6;129P2-Msh2tm1Rak

Strain Type(s)

targeted mutation (knockout)

Strain Synonym(s)

Msh2-deficient  •  Msh2Δ7N/Δ7N

Description

Mice homozygous for a targeted mutation of Msh2. The genetic background was a mix of C57BL/6JIco and 129P2/OlaHsd. Animals were maintained by backcrossing to C57BL/6JIco for 2-7 generations (N2-N7).

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine tumor Intestine

72

References: Smits R, Genes Chromosomes Cancer 2000 Nov;29(3):229-39

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte

72

References: Smits R, Genes Chromosomes Cancer 2000 Nov;29(3):229-39