Strain SummaryB6.129P2-Apctm1Rak/+

Strain Name

B6.129P2-Apctm1Rak/+

Strain Type(s)

congenic  •  targeted mutation (knockout)

Strain Synonym(s)

B6-Apc1638N  •  C57BL/6J-Apctm1Rak/+  •  C57BL/6JIco (B6)-Apc1638N  •  C57BL/6JIco-Apc1638N  •  Apc1638N  •  Apc+/Apc1638N

Description

Heterozygous mice. The genetic background of these mice was congenic C57BL/6JIco. ES-cells of a 129P2/OlaHsd genetic background were used to generate the mutant allele.

Strain Genetics

Apctm1Rak / Apc+

Models

10 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Connective tissue - Fibroblast desmoid Connective tissue - Fibroblast

very high

very high

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Connective tissue - Fibroblast desmoid Connective tissue - Fibroblast X-radiation

very high

very high

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Intestine tumor Intestine

very high

observed

References: Smits R, Carcinogenesis 1997 Feb;18(2):321-7   ⋅   van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Intestine tumor Intestine X-radiation

very high

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Mammary gland carcinoma - adenosquamous Mammary gland

0

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Mammary gland carcinoma - adenosquamous Mammary gland X-radiation

50

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Ovary - Sex cord stromal cell tumor Ovary - Sex cord stromal cell

0

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Ovary - Sex cord stromal cell tumor Ovary - Sex cord stromal cell X-radiation

0

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Skin cyst Skin

very high

high

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8

Skin cyst Skin X-radiation

very high

very high

References: van der Houven van Oordt CW, Genes Chromosomes Cancer 1999 Mar;24(3):191-8