Strain SummaryFVB/NTac

Strain Name

FVB/NTac

Strain Type(s)

inbred

Strain Synonym(s)

FBV/N  •  FVB  •  FVB/N  •  FVB/N from Taconic Farms  •  FVB/N Taconic Farms  •  wild-type FVB/N  •  wt

Models

66 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue liposarcoma Subcutis

1.4

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Adrenal gland - Cortex tumor Adrenal gland - Cortex

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

5.6 - 6

3.6 - 4

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell

83

14

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Blood vessel hemangioma Blood vessel

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Blood vessel hemangioma Ovary

1.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Blood vessel hemangioma Spleen

1.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

CNS - Brain - Undifferentiated cell tumor Skin

2.8

6.9

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

CNS - Brain - Undifferentiated cell tumor Preputial gland (male)

3.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Connective tissue - Fibroblast fibroma Uterus

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Eye - Harderian gland adenoma Eye - Harderian gland

5.6

6.9

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Eye - Harderian gland adenoma - acidophilic Eye - Harderian gland

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Eye - Harderian gland tumor Eye - Harderian gland

6

7

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Gallbladder papilloma Gallbladder

1.4

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell

5.6 - 6

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Leukocyte - Lymphocyte hyperplasia Spleen - White pulp

11

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

observed - 6

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Leukocyte lymphoma Leukocyte

observed

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Liver - Hepatocyte tumor Liver - Hepatocyte

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Liver hepatocellular adenoma Liver

0

17

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Liver hepatocellular carcinoma Liver

0

14

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Sites of Metastasis: Lung

Liver tumor Liver

0

20.0 - 21.0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Lung - Alveolus hyperplasia Lung - Alveolus

11

6.9

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Lung adenoma Lung

18

28

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Lung carcinoma Lung

21

28

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Lung neoplasm Lung

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Lung tumor Lung

2.9 - 37

41

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6   ⋅   Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74

Mammary gland tumor Mammary gland

0 - observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74

Muscle - Smooth leiomyoma Uterus

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Muscle - Smooth leiomyosarcoma Uterus

1.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Neuroectoderm - Neural crest cell tumor Subcutis

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Ovary - Corpus luteum hyperplasia Ovary - Corpus luteum diethylstilbestrol (DES)

observed

References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80

Ovary - Corpus luteum hyperplasia Ovary - Corpus luteum ethinyl estradiol (EE)

observed

References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80

Ovary - Germ cell teratoma Ovary - Germ cell

1.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Ovary - Granulosa cell tumor Ovary - Granulosa cell

2.8

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Ovary - Sertoli cell tumor Ovary - Sertoli cell

1.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Ovary cystadenoma Ovary

1.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Ovary tumor Ovary

observed - 7

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Pancreas - Islet of Langerhans adenoma Pancreas - Islet of Langerhans

0

3.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis

14

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Pituitary gland - Pars distalis hyperplasia Pituitary gland - Pars distalis

7.2

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Pituitary gland - Pars distalis tumor Pituitary gland - Pars distalis

15

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Pituitary gland adenoma Pituitary gland

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Pituitary gland prolactinoma Pituitary gland

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Pituitary gland tumor Pituitary gland

1.9

References: Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74

Placenta - Trophoblast choriocarcinoma Uterus

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Skin - Epidermis squamous cell papilloma Skin - Epidermis

1.4

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Skin carcinoma Skin - Dorsal region 12-O-tetradecanoylphorbol-13-acetate (TPA)

observed

References: Tober KL, Biochem Biophys Res Commun 1998 Jun 29;247(3):644-53

Skin papilloma Skin - Dorsal region 12-O-tetradecanoylphorbol-13-acetate (TPA)

observed

References: Tober KL, Biochem Biophys Res Commun 1998 Jun 29;247(3):644-53

Skin papilloma Skin - Dorsal region ultraviolet radiation (UV)

0 - 10

References: Trempus CS, J Invest Dermatol 1998 Sep;111(3):445-51

Skin papilloma Skin - Dorsal region 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   dimethylbenzanthracene (DMBA)

observed

References: Hansen LA, Carcinogenesis 1996 Sep;17(9):1825-33

Skin squamous cell carcinoma Skin - Dorsal region 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   dimethylbenzanthracene (DMBA)

observed

References: Hansen LA, Carcinogenesis 1996 Sep;17(9):1825-33

Skin tumor Skin wounding

0

References: Cannon RE, Mol Carcinog 1997 Sep;20(1):108-14

Stomach - Glandular carcinoma Stomach - Glandular

0

References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47

Stomach - Glandular carcinoma Stomach - Glandular Helicobacter felis

0

References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47

Stomach - Glandular dysplasia Stomach - Glandular

0

References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47

Stomach - Glandular hyperplasia - foveolar Stomach - Glandular Helicobacter felis

observed

References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47

Stomach - Glandular hyperplasia - foveolar Stomach - Glandular

0

References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47

Stomach - Glandular metaplasia Stomach - Glandular

0

References: Wang TC, Gastroenterology 2000 Jan;118(1):36-47

Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell)

3.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

3.4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Thyroid gland tumor Thyroid gland

0

0

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium diethylstilbestrol (DES)

observed

References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium ethinyl estradiol (EE)

observed

References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80

(Unspecified organ) lesion (Unspecified organ) cyclophosphamide (Cytoxan)

0

References: Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80

(Unspecified organ) tumor (Unspecified organ)

4.8

References: Torres-Arzayus MI, Cancer Cell 2004 Sep;6(3):263-74