Strain Summary(C57BL/6 x C3H)F1

Strain Name

(C57BL/6 x C3H)F1

Strain Type(s)

hybrid

Strain Synonym(s)

B6C3F1  •  B6C3F1 (C3H x C57B16)  •  B6C3F1 hybrid  •  B6C3F1  •  (C57BL/6xC3H)  •  F1-hybrid B6C3F1  •  hybrid B6C3F1

Description

F1 generation of a cross between C57BL/6 and C3H mice. (Substrains not specified.)

Models

1473 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue lipoma Peritoneum - Mesentery

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Adipose tissue lipoma Skin

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Adipose tissue lipoma CNS - Brain

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Adipose tissue lipoma Adipose tissue

0

0

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Adrenal gland - Capsule adenoma Adrenal gland - Capsule

0 - 2

0 - 20

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

0 - 6

0 - 22

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Adrenal gland - Cortex carcinoma Adrenal gland - Cortex

0 - 2

0 - 0.1

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Adrenal gland - Cortex lesion Adrenal gland - Cortex

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Adrenal gland - Cortex tumor Adrenal gland - Cortex

4

References: Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

0 - 6

0 - 5

2

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Adrenal gland - Medulla pheochromocytoma - malignant Adrenal gland - Medulla

0

0.1

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Adrenal gland neoplasia Adrenal gland Aldrin

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland ampicillin

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland bromoethane (ethyl bromide)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland chlorinated paraffins

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland p-Chloroaniline hydrochloride

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Chlorobenzilate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 4-Chloro-m-phenylenediamine

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland C.I. basic red 9 Monohydrochloride (Pararosaniline)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 1,2-dibromo-3-chloropropane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 1,4-Dichlorobenzene (P-Dichlorobenzene )

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Furan

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 4-Hexylresorcinol

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 2-Mercaptobenzothiazole

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 4,4′-methylenedianiline dihydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Oxytetracycline hydrochloride

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Parathion

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Pentachlorophenol, Dowicide EC-7

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Pentachlorophenol, technical

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 3,4,5-trihydroxybenzoate (Propyl gallate)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland reserpine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Rhodamine 6G

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Tetrachlorvinphos (TCVP)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 1,1,2-Trichloroethane (1,1,2-TCA)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland Tris(2-ethylhexyl) phosphate

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland neoplasia Adrenal gland 4-Vinylcyclohexene

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Adrenal gland tumor Adrenal gland single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Adrenal gland tumor Adrenal gland 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel hemangioma Blood vessel

0 - 8

0 - 6.7

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Duddy SK, Toxicol Appl Pharmacol 1999 Apr 15;156(2):106-12   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Blood vessel troglitazone

1.7 - 8.3

1.7 - 3.3

References: Duddy SK, Toxicol Appl Pharmacol 1999 Apr 15;156(2):106-12

Blood vessel hemangioma Salivary gland

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Liver

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Pancreas

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Peritoneum - Mesentery

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Bone marrow

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Lymph node - Mandibular

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Lymph node - Mesenteric

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Lymph node

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Spleen

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Skin

0 - 4

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Testis

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Epididymis

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Nose - Nasal cavity

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Lung

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Kidney

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Urinary bladder

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Uterus

0 - 4

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Ovary

0 - 4

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangioma Blood vessel Helicobacter hepaticus

observed

2

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangioma Blood vessel Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangiosarcoma Blood vessel

0 - 12

0 - 13

observed

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11   ⋅   Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Duddy SK, Toxicol Appl Pharmacol 1999 Apr 15;156(2):106-12   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Blood vessel troglitazone

10 - 27

3.3 - 27

observed

References: Duddy SK, Toxicol Appl Pharmacol 1999 Apr 15;156(2):106-12

Blood vessel hemangiosarcoma Liver

0 - 4

0 - 6

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11   ⋅   Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Liver riddelliine

2

0 - 62

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Blood vessel hemangiosarcoma Liver Elmiron

2 - 8.16

0 - 18

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Blood vessel hemangiosarcoma Blood vessel Elmiron

2 - 8

0 - 18

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Blood vessel hemangiosarcoma Spleen Elmiron

4

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Blood vessel hemangiosarcoma Heart Elmiron

2

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Blood vessel hemangiosarcoma Bone marrow Elmiron

2

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Blood vessel hemangiosarcoma Lymph node - Mesenteric Elmiron

2

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Blood vessel hemangiosarcoma Heart

0 - 2

0 - 2

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Heart 1,3-butadiene

0 - 42

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Blood vessel hemangiosarcoma Intestine - Small Intestine

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Peritoneum - Mesentery

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Bone marrow

0 - 2

0 - 4

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Lymph node - Mesenteric

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Lymph node

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Spleen

0 - 6

0 - 8

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Thymus

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Skin

0 - 2

0 - 4

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Bone

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Muscle - Striated - Skeletal

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Preputial gland (male)

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Testis

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Lung

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Kidney

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Urinary bladder

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Clitoral gland

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Uterus

0 - 4

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma Ovary

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Blood vessel hemangiosarcoma (Unspecified organ) Helicobacter hepaticus   ⋅   chloroprene

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangiosarcoma Blood vessel Helicobacter hepaticus

observed

2

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangiosarcoma Liver Helicobacter hepaticus

4

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangiosarcoma Blood vessel Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangiosarcoma Liver Helicobacter hepaticus   ⋅   chloroprene

10 - 16.33

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel hemangiosarcoma (Unspecified organ) NTP-2000

0

6.67

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Blood vessel hemangiosarcoma (Unspecified organ) O-nitrotoluene   ⋅   NTP-2000

3.39 - 5.08

28.33 - 100

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Blood vessel hemangiosarcoma Muscle - Striated - Skeletal O-nitrotoluene   ⋅   NTP-2000

observed

observed

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Blood vessel hemangiosarcoma Subcutis O-nitrotoluene   ⋅   NTP-2000

observed

observed

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Blood vessel hemangiosarcoma Peritoneum - Mesentery O-nitrotoluene   ⋅   NTP-2000

observed

observed

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Blood vessel neoplasia Blood vessel 2-Biphenylamine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel p-Chloroaniline hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 5-Chloro-O-toluidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 4-Chloro-o-toluidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel Cupferron

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 1,2-dibromoethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 2,7-Dichlorodibenzo-p-dioxin

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 1,1-Dichloroethane

observed

0 - observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 2-Methyl-1-nitroanthraquinone

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel Michler's ketone

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 5-Nitro-o-toluidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel 2,6-toluene diisocyanate (TDI)   ⋅   2,4-toluene diisocyanate (TDI)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasia Blood vessel o-Toluidine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Blood vessel neoplasm Blood vessel Helicobacter hepaticus

8 - 9

2 - 2.4

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel neoplasm Blood vessel Helicobacter hepaticus   ⋅   chloroprene

12 - 53.1

24 - 45.2

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel neoplasm Blood vessel Helicobacter felis   ⋅   chloroprene

16

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Blood vessel tumor Blood vessel

0 - 10

0 - 20

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Blood vessel tumor Blood vessel single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Blood vessel tumor Blood vessel 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone neoplasia Bone Nitrofurantoin

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Bone neoplasia Bone sodium fluoride

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Bone osteosarcoma Bone

0 - 4

0 - 2

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Bone tumor Bone single carcinogen from 185 carcinogen National Toxicology Program pool

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Bone tumor Bone 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain - Astrocyte astrocytoma CNS - Brain - Astrocyte

0

0 - 0.5

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35

CNS - Brain - Oligodendroglial cell oligodendroglioma CNS - Brain - Oligodendroglial cell

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

CNS - Brain neoplasia CNS - Brain 1,2,3-Benzotriazole

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain Bromomethane (methyl bromide)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain Diphenhydramine Hydrochloride

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain Furosemide

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain procarbazine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain neoplasia CNS - Brain Chloroethane

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

CNS - Brain tumor CNS - Brain single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

CNS - Brain tumor CNS - Brain 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland adenoma Clitoral gland

0

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Clitoral gland carcinoma Clitoral gland

0

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Clitoral gland neoplasia Clitoral gland 2-Amino-5-nitrophenol

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland neoplasia Clitoral gland 2,4-Diaminoanisole sulfate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland neoplasia Clitoral gland glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland neoplasia Clitoral gland Nalidixic acid

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland neoplasia Clitoral gland 1,5-naphthalenediamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland neoplasia Clitoral gland 5-nitroacenaphthene

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland neoplasia Clitoral gland 5-Nitro-o-Anisidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Clitoral gland squamous cell carcinoma Clitoral gland

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Clitoral gland tumor Clitoral gland single carcinogen from 185 carcinogen National Toxicology Program pool

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland chlorinated paraffins

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland 4-aminobiphenyl

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland cobalt sulfate heptahydrate

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland agar

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland cytembena

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland allyl isothiocyanate

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland acrylonitrile

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland benzo[a]pyrene (BP) (BaP) (B[a]P)

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Clitoral gland tumor Clitoral gland 2-amino-4-nitrophenol

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Connective tissue - Fibroblast fibroma Skin

0 - 1.0

0 - 10

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibroma Tail

0.5

0

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Connective tissue - Fibroblast fibroma Ear

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Muscle - Striated - Skeletal

0 - 0.5

0 - 2

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Skin

0 - 8

0 - 24

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Stomach - Glandular

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Intestine - Large Intestine

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Pancreas

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Spleen

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Bone

0 - 4

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast fibrosarcoma Ear

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Connective tissue - Fibroblast tumor Connective tissue - Fibroblast

0 - 8

0 - 23

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Ear - Zymbal gland adenoma Ear - Zymbal gland

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Ear - Zymbal gland carcinoma Ear - Zymbal gland

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Ear - Zymbal gland carcinoma Ear - Zymbal gland Helicobacter hepaticus

0

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Ear - Zymbal gland carcinoma Ear - Zymbal gland Helicobacter hepaticus   ⋅   chloroprene

0 - 6

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Ear - Zymbal gland neoplasia Ear - Zymbal gland 3-Amino-9-ethylcarbazole hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland benzene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland C.I. basic red 9 Monohydrochloride (Pararosaniline)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland Cupferron

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 2,4-Diaminoanisole sulfate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 3,3'-Dimethoxybenzidine-4,4'-diisocyanate

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 1,2-Diphenylhydrazine (Hydrazobenzene)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 5-nitroacenaphthene

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 5-Nitro-o-Anisidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 2,2-Bis[(nitrooxy)methyl]propane-1,3-diyl dinitrate (Pentaerythritol tetranitrate)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland 4,4'-Thiodianiline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland neoplasia Ear - Zymbal gland Tris(aziridinyl)-phosphine sulfide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Ear - Zymbal gland tumor Ear - Zymbal gland single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear - Zymbal gland tumor Ear - Zymbal gland 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear squamous cell carcinoma Ear

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Ear tumor Ear single carcinogen from 185 carcinogen National Toxicology Program pool

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor Ear 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Ear tumor - basosquamous Ear

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Epididymis neoplasia Epididymis glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Esophagus neoplasia Esophagus Dichlorvos

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Esophagus neoplasia Esophagus Dimethylvinyl chloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Esophagus squamous cell carcinoma Esophagus

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Esophagus tumor Esophagus single carcinogen from 185 carcinogen National Toxicology Program pool

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Esophagus tumor Esophagus single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland adenocarcinoma Eye - Harderian gland

observed

References: Goodrow TL, Carcinogenesis 1994 Nov;15(11):2665-7

Eye - Harderian gland adenocarcinoma Eye - Harderian gland 1,3-butadiene

observed

References: Goodrow TL, Carcinogenesis 1994 Nov;15(11):2665-7

Eye - Harderian gland adenoma Eye - Harderian gland 1,3-butadiene

observed

observed

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Goodrow TL, Carcinogenesis 1994 Nov;15(11):2665-7   ⋅   Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Eye - Harderian gland adenoma Eye - Harderian gland

0 - 16

0 - 18

observed

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Goodrow TL, Carcinogenesis 1994 Nov;15(11):2665-7   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41   ⋅   Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Eye - Harderian gland adenoma Eye - Harderian gland isoprene

observed

References: Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Eye - Harderian gland adenoma Eye - Harderian gland Helicobacter hepaticus

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Eye - Harderian gland adenoma Eye - Harderian gland Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Eye - Harderian gland carcinoma Eye - Harderian gland

0 - 4

0 - 6

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Eye - Harderian gland carcinoma Eye - Harderian gland 1,3-butadiene

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Eye - Harderian gland carcinoma Eye - Harderian gland Helicobacter hepaticus

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Eye - Harderian gland carcinoma Eye - Harderian gland Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Eye - Harderian gland neoplasia Eye - Harderian gland benzene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland Cupferron

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland ethylene oxide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland Ethyl tellurac

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland 4-Hexylresorcinol

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland Iodinated glycerol

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland N-methyloacrylamide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland 4,4'-Oxydianiline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasia Eye - Harderian gland Tris(2-chloroethyl) phosphate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Eye - Harderian gland neoplasm Eye - Harderian gland Helicobacter hepaticus

4 - 4.5

4 - 4.7

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Eye - Harderian gland neoplasm Eye - Harderian gland Helicobacter hepaticus   ⋅   chloroprene

6 - 31.2

10 - 32

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Eye - Harderian gland tumor Eye - Harderian gland

4 - 18

5 - 13

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Goodrow TL, Carcinogenesis 1994 Nov;15(11):2665-7   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Eye - Harderian gland tumor Eye - Harderian gland 1,3-butadiene

14 - 67

15 - 77

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Goodrow TL, Carcinogenesis 1994 Nov;15(11):2665-7

Eye - Harderian gland tumor Eye - Harderian gland single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland acrylonitrile

0

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Harderian gland tumor Eye - Harderian gland 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Eye - Uvea - Melanocyte melanoma Eye - Uvea - Melanocyte

0.5

0

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Forestomach hyperplasia - epithelial Forestomach Helicobacter hepaticus

8

8

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Forestomach hyperplasia - epithelial Forestomach Helicobacter hepaticus   ⋅   chloroprene

6 - 54

13 - 58

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Forestomach lesion Forestomach Helicobacter hepaticus

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Forestomach lesion Forestomach Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Forestomach neoplasia Forestomach Allyl chloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Benzaldehyde

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach benzofuran

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Benzyl acetate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach bis(2-chloro-1-methylethyl) ether

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 3-Chloro-2-methylpropene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 3-(Chloromethyl)pyridine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 4-Chloro-m-phenylenediamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Disperse yellow 3

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Cupferron

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Diallyl phthalate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 1,2-dibromo-3-chloropropane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 1,2-dibromoethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 1,2-dichloroethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Dichlorvos

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Diglycidyl resorcinol ether

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Dimethoxane

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach N,N-Dimethylaniline

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Dimethyl hydrogen phosphite

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Dimethylvinyl chloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach estradiol mustard

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Ethyl acrylate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Furan-2-carbaldehyde (Furfural)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Iodinated glycerol

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Pivalolactone

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach sulfallate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach Trifluralin

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach TRIS(2,3-dibromopropyl) phosphate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach neoplasia Forestomach 1,3-dichloropropene (telone II)

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Forestomach squamous cell carcinoma Forestomach

0 - 2

0 - 2

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Forestomach squamous cell carcinoma Forestomach 1,3-butadiene

0 - observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Forestomach squamous cell papilloma Forestomach

0 - 6

0 - 6

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Forestomach squamous cell papilloma Forestomach 1,3-butadiene

0 - observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Forestomach squamous cell papilloma Forestomach Helicobacter hepaticus

0

2 - 2.4

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Forestomach squamous cell papilloma Forestomach Helicobacter hepaticus   ⋅   chloroprene

0 - 14.6

0 - 10.8

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Forestomach tumor Forestomach isoprene

observed

References: Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Forestomach tumor Forestomach 1,3-butadiene

0 - 8

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Forestomach tumor Forestomach

0

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Forestomach tumor Forestomach single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach acrylonitrile

0

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach benzo[a]pyrene (BP) (BaP) (B[a]P)

0 - observed

0 - observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Acetaldeyde methylformylhydrazine

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Acetone[4-(5nitro2furyl)-2-thyazolyl]-hydrazone

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1-Acetoxysafrole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Amino-4-(5-nitro-2-furyl)-thiazole

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Amino-3,4-dimethylimidazo(4,5-f )-quinoline

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Amino-5-(5-nitro-2-furyl)1,3,4-thiadiazole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1-Amino-2,4-dibromoantraquinone

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Amino-3-methylimidazo(4,5-f )-quinoline

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Amino-5(5-nitro-2-furyl)1,3,4-oxadiazole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1-Amyl-1-nitrosourea

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Benzaldehyde

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach benzofuran

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Benzyl acetate

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Benzyl chloride

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2,2-bis(Bromomethyl)-1,3-propanediol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Bromoethanol

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Butyl-N-nitrosourea

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Butylated hydroxyanisole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1,1-di-n-Butylhydrazine

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Captafol

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Carbazol

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 3-Chloro-2-methylpropene

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 4-Chloro-o-phenylenediamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach chloroprene

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Chloropropanal

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1-Chloropropene

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Ci Direct Blue 218

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Cupferron

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1,1-Diallylhydrazine

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2,3-dibromo-1-propanol

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1,2-dichloroethane

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Dichlorvos

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Diglycidyl resorcinol ether

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach dimethyl hydrogen phosphite

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Dimethylvinyl chloride

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Dinitrosopiperazine

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Ethyl acrylate

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Formic acid 2-[4(5-nitro-2-furyl)-2- 1 1 thiazolyl]hydrazide

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Furan-2-carbaldehyde (Furfural)

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach glycidol

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Hydrazino-4-(p-nitrophenyl)-thiazole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach n-Hydroxy-2-acetylaminofluorene

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1'-Hydroxysafrole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Iodinated glycerol

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1-Methyl-1,4-dihydro-7-[2-(5-nitrofutyl)vinyl]-4-oxo-1,8-naphthyridine-3-carboxylate,potassium

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Mercuric chloride

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Methyl-N-nitrosobenzamide

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2-Methyl-1-nitroantraquinone

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Methylnitrosocianamide

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-[5-(5-nitro-2-furyl)-1,3,4-thiadiazol- 1 1 2-yl] acetamide

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 4-(5-nitro-2-furyl)-thiazole

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 8-Nitroquinoline

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Nitroso-N-methyl-N-(2-phenyl)ethylamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitroso-N-methyl-N-dodecylamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitroso-N-methyldecylamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Nitroso-baygon

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitroso-2,3-dihydroxypropyl-2-hydroxypropylamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1-Nitroso-3,5-dimethyl-4-benzoylpiperazine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Nitroso-2,3-dihydroxypropyl-2-oxopropylamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Nitrosoamylurethane

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitrosobenzothiazuron

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Nitrosodibutylamine

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitrosodiethylamine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitrosoephedrine

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Nitrosoethylurethane

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach N-Nitrosopiperidine

0

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Pivalolactone

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Propiolactone beta

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Styrene oxide

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach sulfallate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1,3-dichloropropene (telone II)

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 1,2,3-Trichloropropane

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach 2,2,2-Trifluoro-N- 1[4-(5-nitro-2-furyl)-2-thiazolyl]acetamide

observed

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Forestomach tumor Forestomach Trifluralin

0

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Gallbladder adenoma Gallbladder

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Gallbladder tumor Gallbladder single carcinogen from 185 carcinogen National Toxicology Program pool

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Gallbladder tumor Gallbladder single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Gastrointestinal tract tumor Gastrointestinal tract

0

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Heart neoplasia Heart 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Heart neoplasia Heart estradiol mustard

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Heart neoplasia Heart phenesterin

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine - Large Intestine - Cecum carcinoma Intestine - Large Intestine - Cecum NTP-2000

0

0

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Intestine - Large Intestine - Cecum carcinoma Intestine - Large Intestine - Cecum O-nitrotoluene   ⋅   NTP-2000

1.69 - 6.78

0 - 20

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine - Large Intestine squamous cell carcinoma Intestine - Large Intestine

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine

0.1

0.7

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Intestine - Small Intestine adenoma Intestine - Small Intestine

0 - 2

0 - 4

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Intestine - Small Intestine carcinoma Intestine - Small Intestine

0 - 6

0 - 6

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Intestine neoplasia Intestine Bromodichloromethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine neoplasia Intestine (3aR,7aS)-2-[(Trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (Captan)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine neoplasia Intestine glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine neoplasia Intestine phenazopyridine

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine neoplasia Intestine Proflavine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine neoplasia Intestine 4,4'-Thiodianiline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine neoplasia Intestine Tribromomethane

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Intestine tumor Intestine single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Intestine tumor Intestine 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney - Renal tubule adenoma Kidney - Renal tubule

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Kidney - Renal tubule adenoma Kidney - Renal tubule Helicobacter hepaticus

0.2

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney - Renal tubule carcinoma Kidney - Renal tubule

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Kidney - Renal tubule hyperplasia Kidney - Renal tubule Helicobacter hepaticus

4

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney - Renal tubule hyperplasia Kidney - Renal tubule Helicobacter hepaticus   ⋅   chloroprene

33 - 36

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney - Renal tubule lesion Kidney - Renal tubule Helicobacter hepaticus

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney - Renal tubule lesion Kidney - Renal tubule Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney adenoma Kidney Helicobacter hepaticus

0

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney adenoma Kidney Helicobacter hepaticus   ⋅   chloroprene

4.08 - 23.9

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Kidney neoplasia Kidney 1-Amino-2-methyl-anthraquinone

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 2-amino-4-nitrophenol

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney o-Anisidine Hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney caffeine   ⋅   aspirin (acetylsalicylic acid) (ASA)   ⋅   phenacetin

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney benzofuran

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Bromodichloromethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney chlorinated paraffins

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 2,4,5,6-tetrachloroisophthalonitrile (Chlorothalonil)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Acid Orange 3

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Pigment Red 23

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Cinnamyl anthranilate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 2,4-Diaminophenol dihydrochloride

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 1,4-Dichlorobenzene (P-Dichlorobenzene )

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Furan-2-carbaldehyde (Furfural)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Furosemide

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 3,7-Dimethyl-2,6-octadien-1-yl acetate (Geranyl acetate)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney hydroquinone (HQ)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 3,5,5-Trimethylcyclohex-2-en-1-one (Isophorone)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney d-limonene

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney α-Methylbenzyl alcohol

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Methyldopa sesquihydrate

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney 3-(4-Chlorophenyl)-1,1-dimethylurea (Monuron)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Nitrilotriacetic acid (NTA)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Nitrilotriacetic acid trisodium salt monohydrate

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Nitrofurantoin

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Phenylbutazone

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney N-Phenyl-2-naphthylamine

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney tetrachloroethylene (TCE)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Tris(2-chloroethyl) phosphate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney TRIS(2,3-dibromopropyl) phosphate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney neoplasia Kidney Dimethyl methylphosphonate

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Kidney transitional cell carcinoma Kidney

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Kidney tumor Kidney single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Kidney tumor Kidney 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell myeloma Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

0.5

0

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0 - 10

0 - 6

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte 1,3-butadiene

4 - 14

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung

1.7

1.0

References: Dixon D, Toxicol Pathol 2008;36(3):428-39

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Heart

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Liver

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Pancreas

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Peritoneum - Mesentery

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Lymph node - Mesenteric

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Lymph node

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Thymus

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Skin

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Epididymis

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Lung

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Ear

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Uterus

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytoma - fibrous - malignant Ovary

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Forestomach

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Bone marrow

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node - Mandibular

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Spleen

0 - 2

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Thymus

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lung

0 - 2

0

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte leukemia Leukocyte

0 - 2.1

0 - 0.7

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Leukocyte lymphoma Leukocyte

6 - 62

2 - 32

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6

Leukocyte lymphoma Leukocyte 1,3-butadiene

14 - 24

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Leukocyte lymphoma Lung

19.2

4.1

References: Dixon D, Toxicol Pathol 2008;36(3):428-39

Leukocyte lymphoma Leukocyte (see notes regarding diet)

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Leukocyte lymphoma - lymphocytic Leukocyte

6.5

1.0

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Leukocyte lymphoma - mixed Leukocyte

10

4.5

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Leukocyte neoplasm Leukocyte

22.5

9.0

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8

Leukocyte tumor - malignant Leukocyte

27.2

12.7

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Liver - Bile duct cholangiocarcinoma Liver - Bile duct

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Liver - Bile duct cholangioma Liver - Bile duct

0

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Liver - Bile duct cholangioma Liver - Bile duct riddelliine

2

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Liver - Bile duct cholangioma Liver - Bile duct single carcinogen from 185 carcinogen National Toxicology Program pool

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct chlorinated paraffins

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct cholangioma Liver - Bile duct 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct hyperplasia Liver - Bile duct

0

4

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Liver - Bile duct hyperplasia Liver - Bile duct riddelliine

56

0 - 12

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Liver - Bile duct hyperplasia Liver - Bile duct Helicobacter hepaticus

0

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver - Bile duct tumor Liver - Bile duct single carcinogen from 185 carcinogen National Toxicology Program pool

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Bile duct tumor Liver - Bile duct single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver - Hepatocyte foci - basophilic Liver - Hepatocyte

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Hepatocyte foci - basophilic Liver - Hepatocyte N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Hepatocyte foci - basophilic Liver - Hepatocyte phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Hepatocyte foci - eosinophilic Liver - Hepatocyte phenobarbital (PB)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Hepatocyte foci - eosinophilic Liver - Hepatocyte phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Sinusoid - Ito cell tumor Liver - Sinusoid - Ito cell

0

0 - 2

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Liver adenoma Liver

0 - 50

0 - 60

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Liver adenoma Liver single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver chlorinated paraffins

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver adenoma Liver 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver carcinoma Liver

0 - 38

6 - 36

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Liver carcinoma Liver single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver carcinoma Liver single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver foci Liver

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver foci Liver 2,3,7,8-tetrachorodibenzo-p-dioxin (TCDD)

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver foci Liver phenobarbital (PB)

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver hepatoblastoma Liver

0 - 2

0 - 2

References: Anna CH, Cancer Res 2000 Jun 1;60(11):2864-8   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Liver hepatoblastoma Liver 8 oxazepam

2 - 16

4 - 40

References: Anna CH, Cancer Res 2000 Jun 1;60(11):2864-8

Liver hepatoblastoma Liver anthraquinone

0 - 2

10 - 43

References: Anna CH, Cancer Res 2000 Jun 1;60(11):2864-8

Liver hepatocellular adenoma Liver N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver hepatocellular adenoma Liver phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver hepatocellular adenoma Liver

observed - 14

observed - 38

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11   ⋅   Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Liver hepatocellular adenoma Liver 2,3,7,8-tetrachorodibenzo-p-dioxin (TCDD)

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver hepatocellular adenoma Liver phenobarbital (PB)

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver hepatocellular adenoma Liver chlordane

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver hepatocellular adenoma Liver anthraquinone

observed

References: Anna CH, Cancer Res 2000 Jun 1;60(11):2864-8

Liver hepatocellular adenoma Liver Elmiron

10.2 - 30.61

30 - 40

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Liver hepatocellular adenoma Liver 1,3-butadiene

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Liver hepatocellular adenoma Liver Helicobacter hepaticus

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver hepatocellular adenoma Liver Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver hepatocellular carcinoma Liver

observed - 4.5

observed - 9.5

References: Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Sites of Metastasis: Lung

Liver hepatocellular carcinoma Liver phenobarbital (PB)

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90   ⋅   Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver hepatocellular carcinoma Liver N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Sites of Metastasis: Lung

Liver hepatocellular carcinoma Liver phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Sites of Metastasis: Lung

Liver hepatocellular carcinoma Liver 2,3,7,8-tetrachorodibenzo-p-dioxin (TCDD)

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver hepatocellular carcinoma Liver chlordane

observed

References: Christensen JG, Carcinogenesis 1999 Aug;20(8):1583-90

Liver hepatocellular carcinoma Liver anthraquinone

observed

References: Anna CH, Cancer Res 2000 Jun 1;60(11):2864-8

Liver hepatocellular carcinoma Liver 1,3-butadiene

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Liver hepatocellular carcinoma Liver Helicobacter hepaticus

8 - 9

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver hepatocellular carcinoma Liver Helicobacter hepaticus   ⋅   chloroprene

22.45 - 58.2

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver hepatocellular tumor Liver anthraquinone

observed

References: Anna CH, Cancer Res 2000 Jun 1;60(11):2864-8

Liver hepatocellular tumor Liver

20 - 32.65

46 - 72

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11   ⋅   Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Liver hepatocellular tumor Liver riddelliine

0

6 - 78

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Liver hepatocellular tumor Liver Elmiron

16.33 - 36.73

46 - 62

References: Abdo KM, Arch Toxicol 2003 Dec;77(12):702-11

Liver hepatocholangiocarcinoma Liver

0 - 4

0 - 6

References: Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Liver hepatoma Liver (see notes regarding diet)

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Liver lesion Liver single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver lesion Liver single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver neoplasia Liver Aldrin

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2-Aminoanthraquinone

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 3-Amino-9-ethylcarbazole hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1-Amino-2-methyl-anthraquinone

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 11-Aminoundecanoic acid

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver benzofuran

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Benzyl acetate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver bis(2-chloro-1-methylethyl) ether

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Bromodichloromethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 3-Amino-2,5-dichlorobenzoic acid (Chloramben)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver chlordane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver chlorendic acid

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver chlorinated paraffins

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver p-Chloroaniline hydrochloride

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Chlorobenzene

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Chlorobenzilate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Chlorodibromomethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4-Chloro-m-phenylenediamine

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4-Chloro-o-phenylenediamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 5-Chloro-O-toluidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver C.I. basic red 9 Monohydrochloride (Pararosaniline)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Disperse Blue 1

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Disperse yellow 3

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Sudan I (Solvent Yellow 14)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Cinnamyl anthranilate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver p-cresidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Cupferron

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4-(2,2-Dimethylhydrazinyl)-4-oxobutanoic acid (Daminozide)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver D and C Red No. 9

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,3,4,5,6-Pentabromo-1-(2,3,4,5,6-pentabromophenoxy)benzene (Decabromodiphenyl ether/oxide)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,4-diaminotoluene (2,4- DAT)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,2-dibromoethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,4-Dichlorobenzene (P-Dichlorobenzene )

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,7-Dichlorodibenzo-p-dioxin

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver p,p'-Dichlorodiphenyldichloroethylene (DDE)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,6-Dichloro-p-phenylenediamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,2-Dichloropropane (Propylene dichloride)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,2,2-trichloro-1,1-bis(4-chlorophenyl)ethanol (Dicofol)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver (1aR,2R,2aS,3S,6R,6aR,7S,7aS)-3,4,5,6,9,9-hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-dimethanonaphtho[2,3-b]oxirene (Dieldrin)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Bis(2-ethylhexyl) adipate (Di(2-ethylhexyl)adipate)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver diethylhexylphthalate (DEHP)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,1-Dichloro-2,2-bis(4-ethylphenyl)ethane

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,4-dioxane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,5-Dithiobiurea

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Imidazolidine-2-thione (1,3-Ethylene-2-thiourea, N,N-Ethylenethiourea, Ethylene thiourea, ETU)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2-Methoxy-4-(prop-2-en-1-yl)phenol (Eugenol)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,1-Dimethyl-3-[3-(trifluoromethyl)phenyl]urea (Fluometuron)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Furan

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Furan-2-carbaldehyde (Furfural)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver HC Blue 1

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver HC Red 3

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,4,5,6,7,8,8-Heptachloro-3a,4,7,7a-tetrahydro-4,7-methano-1H-indene (Heptachlor)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Hexachloroethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,2-Diphenylhydrazine (Hydrazobenzene)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Hydrochlorothiazide

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver hydroquinone (HQ)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 3,5,5-Trimethylcyclohex-2-en-1-one (Isophorone)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2-Mercaptobenzothiazole

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver methyl carbamate

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4,4′-Methylenebis(N,N-dimethylaniline) benzenamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver methylene chloride (MC)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4,4′-methylenedianiline dihydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2-Methyl-1-nitroanthraquinone

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver N-methyloacrylamide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Michler's ketone

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 3-(4-Chlorophenyl)-1,1-dimethylurea (Monuron)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,5-naphthalenediamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Nithiazide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 5-nitroacenaphthene

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 3-Nitro-p-acetophenetide

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 5-Nitro-o-Anisidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 6-Nitrobenzimidazole

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,4-Dichloro-1-(4-nitrophenoxy)benzene (Nitrofen)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2-Nitro-1,4-phenylenediamine

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 3-Nitropropionic acid

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver p-Nitrosodiphenylamine

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 5-Nitro-o-toluidine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4,4'-Oxydianiline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Pentachlorophenol, Dowicide EC-7

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Pentachlorophenol, technical

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver phenazopyridine

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Phenylbutazone

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid (Picloram)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Piperonyl sulfoxide

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Polybrominated biphenyl mix (FF1)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Probenecid

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Proflavine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver selenium sulfide

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,3,7,8-tetrachorodibenzo-p-dioxin (TCDD)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,1,2,2-Tetrachloroethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver tetrachloroethylene (TCE)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Tetrachlorvinphos (TCVP)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 4,4'-Thiodianiline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,4-toluene diisocyanate (TDI)   ⋅   2,6-toluene diisocyanate (TDI)

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver o-Toluidine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Toxaphene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,1,2-Trichloroethane (1,1,2-TCA)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver trichloroethene (Trichloroethylene)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,4,6-Trichlorophenol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Trifluralin

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 2,4,5,-trimethylaniline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver TRIS(2,3-dibromopropyl) phosphate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Tris(2-ethylhexyl) phosphate

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver (3S,11E)-14,16-Dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione (Zearalenone)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver Chloroethane

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasia Liver 1,3-dichloropropene (telone II)

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Liver neoplasm Liver Helicobacter hepaticus

40 - 44.8

86

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver neoplasm Liver Helicobacter hepaticus   ⋅   chloroprene

40 - 79.7

74 - 84

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Liver neoplasm Liver

7.9

31.1

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Liver neoplasm - benign Liver

4.0

10.3

References: Haseman JK, Toxicol Pathol 1984;12(2):126-35

Liver tumor Liver isoprene

observed

References: Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Liver tumor Liver 1,3-butadiene

28.57 - 38

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Liver tumor Liver

3 - 56

10 - 70

0

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41   ⋅   Mahler JF, Toxicol Pathol 1996 Nov-Dec;24(6):710-6   ⋅   Tao L, Toxicology 2004 Mar 1;196(1-2):127-36

Liver tumor Liver 7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Kalkuhl A, Hepatology 1998 Apr;27(4):1081-8

Liver tumor Liver N-methyl-N-nitrosourea (MNU)

0

References: Tao L, Toxicology 2004 Mar 1;196(1-2):127-36

Liver tumor Liver N-methyl-N-nitrosourea (MNU)   ⋅   dichloroacetic acid

observed

References: Tao L, Toxicology 2004 Mar 1;196(1-2):127-36

Liver tumor Liver N-methyl-N-nitrosourea (MNU)   ⋅   trichloroacetic acid

observed

References: Tao L, Toxicology 2004 Mar 1;196(1-2):127-36

Liver tumor Liver dichloroacetic acid

0

References: Tao L, Toxicology 2004 Mar 1;196(1-2):127-36

Liver tumor Liver trichloroacetic acid

0

References: Tao L, Toxicology 2004 Mar 1;196(1-2):127-36

Liver tumor Liver single carcinogen from 185 carcinogen National Toxicology Program pool

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver single carcinogen from 536 carcinogen pool that includes the 185 National Toxicology Program carcinogens

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver chlorinated paraffins

observed

observed

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver 4-aminobiphenyl

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver cobalt sulfate heptahydrate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver agar

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver cytembena

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver allyl isothiocyanate

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver acrylonitrile

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver benzo[a]pyrene (BP) (BaP) (B[a]P)

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver 2-amino-4-nitrophenol

0

0

References: Benigni R, Mutat Res 1998 Oct 12;421(1):93-107

Liver tumor Liver NTP-2000

15.25

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Liver tumor Liver O-nitrotoluene   ⋅   NTP-2000

15.25 - 66.10

References: Dunnick JK, Toxicology 2003 Feb 1;183(1-3):221-34

Lung - Bronchiole hyperplasia Lung - Bronchiole Helicobacter hepaticus

0

0

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung - Bronchiole hyperplasia Lung - Bronchiole Helicobacter hepaticus   ⋅   chloroprene

24 - 60

20 - 46

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung - Bronchiole lesion Lung - Bronchiole Helicobacter hepaticus

0

0

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung - Bronchiole lesion Lung - Bronchiole Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung adenocarcinoma Lung

observed

observed

References: Devereux TR, Carcinogenesis 1997 Sep;18(9):1751-5   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Lung adenocarcinoma Lung 1,3-butadiene

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Lung adenoma Lung riddelliine

18

18 - 34

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Lung adenoma Lung

0 - 24

4 - 36

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311   ⋅   Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Dixon D, Toxicol Pathol 2008;36(3):428-39   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Lung adenoma Lung 1,3-butadiene

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Lung adenoma Lung beta-myrcene

observed

References: Dixon D, Toxicol Pathol 2008;36(3):428-39

Lung adenoma Lung Helicobacter hepaticus

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung adenoma Lung Helicobacter hepaticus   ⋅   chloroprene

observed

observed

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung adenoma Lung (see notes regarding diet)

observed

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Lung carcinoma Lung

0 - 12

0 - 16

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311   ⋅   Chandra M, Toxicol Lett 1992 Jan;60(1):91-8   ⋅   Dixon D, Toxicol Pathol 2008;36(3):428-39   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Haseman JK, Toxicol Pathol 1984;12(2):126-35   ⋅   Haseman JK, Toxicol Pathol 1998 May-Jun;26(3):428-41

Lung carcinoma Lung riddelliine

8

References: Chan PC, Toxicol Lett 2003 Oct 15;144(3):295-311

Lung carcinoma Lung 1,3-butadiene

observed

References: Dixon D, Toxicol Pathol 2008;36(3):428-39   ⋅   Fred C, Cancer Res 2008 Oct 1;68(19):8014-21

Lung carcinoma Lung 1,2-dibromoethane

observed

References: Dixon D, Toxicol Pathol 2008;36(3):428-39

Lung carcinoma Lung Helicobacter hepaticus

4 - 4.6

12 - 14.1

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung carcinoma Lung Helicobacter hepaticus   ⋅   chloroprene

28.57 - 76

24 - 66.4

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung neoplasia Lung benzene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung benzofuran

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,2,3-Benzotriazole

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung bis(2-chloro-1-methylethyl) ether

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Bromomethane (methyl bromide)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,3-butadiene

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung chlorendic acid

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Disperse Blue 1

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,2-dibromo-3-chloropropane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,2-dibromoethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,2-dichloroethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Dimethyl hydrogen phosphite

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Dimethyl benzene-1,4-dicarboxylate (Dimethyl terephthalate)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Diphenhydramine Hydrochloride

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,2-epoxybutane

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung estradiol mustard

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung ethylene oxide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung glycidol

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung HC Blue 1

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung methylene chloride (MC)

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung N-methyloacrylamide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung naphthalene

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,5-naphthalenediamine

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 5-nitroacenaphthene

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung phenesterin

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung procarbazine hydrochloride

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung selenium sulfide

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Ethenylbenzene (Styrene)

0

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung sulfallate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung tetranitromethane

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Trifluralin

observed

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 2,4,5,-trimethylaniline

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung TRIS(2,3-dibromopropyl) phosphate

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 4-vinyl-1-cyclohexene diepoxide

observed

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung Zinc; N,N-dimethylcarbamodithioate (Ziram)

0

0

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasia Lung 1,3-dichloropropene (telone II)

observed

References: Huff J, Environ Health Perspect 1991 Jun;93():247-70

Lung neoplasm Lung Helicobacter hepaticus

8 - 9.1

26 - 29.8

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung neoplasm Lung Helicobacter hepaticus   ⋅   chloroprene

57.14 - 96.1

56 - 92.9

References: Melnick RL, Carcinogenesis 1999 May;20(5):867-78

Lung squamous cell carcinoma Lung

0

References: Dixon D, Toxicol Pathol 2008;36(3):428-39

Lung squamous cell carcinoma Lung (see notes)

0

References: Dixon D, Toxicol Pathol 2008;36(3):428-39

Lung tumor Lung isoprene

observed

References: Hong HL, Carcinogenesis 1997 Apr;18(4):783-9

Lung tumor Lung 1,3-butadiene

30 - 51.02

observed

References: Fred C, Cancer Res 2008 Oct 1;68(19):8014-21   ⋅   Hong HL, Carcinogenesis 1997 Apr;18(4):783-9