Strain SummaryC57L/J

Strain Name

C57L/J

Strain Type(s)

inbred

Strain Synonym(s)

C57L  •  C57 leaden  •  C57L/HeJax  •  C57L/Jax  •  C57L/J, H-2b  •  L  •  leaden  •  Leaden

Models

134 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue - White lipoma Adipose tissue - White

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma - pedunculated Adipose tissue

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell

low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - nodular Adrenal gland

very low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - spindle cell Adrenal gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Adrenal gland tumor - carcinoid Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Liver

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone hyperplasia Bone

very low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone lesion - fibro-osseous Bone

0 - very low

0

00 - 3.45

References: Berndt A, Exp Mol Pathol 2015 Nov 14;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Epididymis cyst Epididymis

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte leukemia - erythroleukemia Spleen

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte neoplasm Erythrocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Esophagus hyperplasia Esophagus

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach hyperplasia - papillary Forestomach

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach papilloma Forestomach

0

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder cyst Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder hyperplasia Gallbladder

0 - observed

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

2 pathology image(s)

Gallbladder hyperplasia - papillary Gallbladder

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gastrointestinal tract carcinoma Gastrointestinal tract N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

observed

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum

observed - very low

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

3 pathology image(s)

Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Kidney adenoma Kidney

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus

0

References: Angel JM, J Natl Cancer Inst 1989 Nov 1;81(21):1652-5

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus N-methyl-N-nitrosourea (MNU)

0 - 39

References: Angel JM, J Natl Cancer Inst 1989 Nov 1;81(21):1652-5

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

11.11

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte leukemia Leukocyte 1-ethyl-1-nitrosourea (ENU)

21

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Leukocyte leukemia Leukocyte

0 - 7.0

1.3

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70   ⋅   Myers DD, Life Sci 1970;9(Pt II):1071-80

Leukocyte leukemia Leukocyte Friend leukemia virus - "regressing" (RFV)

0

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte leukemia Leukocyte Friend leukemia virus - "conventional" (CFV)

0

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte lymphoma Leukocyte

observed - moderate

low

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct adenoma Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct hyperplasia Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver hepatoma Liver

0

very low - high

References: Russell ES, 1966;():511-519   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver tumor Liver 1-ethyl-1-nitrosourea (ENU)

2.7

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Lung adenoma Lung 1-ethyl-1-nitrosourea (ENU)

6.7

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Lung adenoma Lung

observed - very low

observed - low

0

References: Berndt A, Cancer Res 2011 Sep 1;71(17):5779-91   ⋅   Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

5 pathology image(s)

Lung adenoma Lung urethane (ethyl carbamate)

10

References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6

Lung carcinoma Lung N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Lung hyperplasia Lung

0 - observed

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lung tumor Lung

1

References: Ryan J, J Natl Cancer Inst 1987 Dec;79(6):1351-7

Lung tumor Lung urethane (ethyl carbamate)

10

References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93

Lymph node cyst Lymph node

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymph node hyperplasia Reticulocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymphoid tissue lymphoma Lymph node

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Mammary gland hyperplasia Mammary gland

observed - 33

References: Felicio LS, Exp Gerontol 1980;15(2):139-43   ⋅   Sundberg J, MGI Direct Data Submission 2007;():

Mammary gland tumor Mammary gland

1

low

References: Bradlow HL, Proc Natl Acad Sci U S A 1985 Sep;82(18):6295-9   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():

Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Seminal vesicle

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Stomach - Glandular

very low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Urinary bladder

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mouth - Oral mucosa cyst Mouth - Oral mucosa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyoma Vagina

very low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal

0

References: Sher RB, PLoS One 2011;6(8):e23498

Myoepithelial cell myoepithelioma Lung

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Myoepithelial cell myoepithelioma Mammary gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Nail squamous cell carcinoma Nail

0

very low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Follicle cyst - follicular Ovary - Follicle

high

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Luteal cell tumor Ovary - Luteal cell

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary adenoma Ovary

very low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary cyst - bursal Ovary

observed - low

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary hyperplasia - epithelial Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary papilloma Ovary

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

2 pathology image(s)

Ovary tumor Ovary 1-ethyl-1-nitrosourea (ENU)

2.7

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Ovary tumor - tubulostromal Ovary

very low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Duct adenoma Pancreas - Duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Pancreas hyperplasia Pancreas

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Pituitary gland adenoma Pituitary gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Pituitary gland tumor Pituitary gland

33

observed

References: Felicio LS, Exp Gerontol 1980;15(2):139-43   ⋅   Murphy ED, 1966;():521-62   ⋅   Staats J, Companion to Mouse News Lett No. 29 1963;():

Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis cyst - inclusion Skin - Epidermis

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin tumor Skin

38

35

References: Staats J, Companion to Mouse News Lett No. 21 1959;():

Skin tumor Skin 3-methylcholanthrene (MCA) (3-MC)

46

References: Whitmire CE, J Natl Cancer Inst 1971 Dec;47(6):1255-65

Stomach - Glandular adenoma Stomach - Glandular

0

observed - very low

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst - glandular Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia Stomach - Glandular

low

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular

low

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular polyp Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Tail hyperplasia Tail

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Thyroid gland hyperplasia - cystic Thyroid gland

low

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter - Transitional cell hyperplasia Ureter - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter hyperplasia Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter polyp Ureter

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder papilloma Urinary bladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium

observed - moderate

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus adenoma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus fibropapilloma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vagina hyperplasia Vagina

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Vagina papilloma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vagina squamous cell carcinoma Vagina

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Vulva squamous cell carcinoma Vulva

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

(Unspecified organ) tumor (Unspecified organ) 1-ethyl-1-nitrosourea (ENU)

5.3

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70