Mouse Tumor Biology Database (MTB)
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Last Database Update
2019-10-20
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
C57L/J
Strain Synonyms C57L  •  C57 leaden  •  C57L/HeJax  •  C57L/Jax  •  C57L/J, H-2b  •  L  •  leaden  •  Leaden
Strain Tumor Overview Expanded View
Tumors 132 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous) 2 0
Adipose tissue lipoma Peritoneal cavity None (spontaneous) 2 0
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous) 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 2 0
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 2 0
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous) 2 0 - low
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous) 2 0 - very low
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous) 2 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous) 2 0
Blood vessel hemangioma Blood vessel None (spontaneous) 2 0
Blood vessel hemangioma Uterus None (spontaneous) 1 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 2 0
Blood vessel hemangiosarcoma Liver None (spontaneous) 2 0
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Bone hyperplasia Bone None (spontaneous) 2 0 - very low
Bone lesion - fibro-osseous Bone None (spontaneous) 11 0 - very low
Epididymis cyst Epididymis None (spontaneous) 1 0
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous) 2 0
Erythrocyte neoplasm Erythrocyte None (spontaneous) 2 0
Esophagus hyperplasia Esophagus None (spontaneous) 2 0
Forestomach hyperplasia - papillary Forestomach None (spontaneous) 2 0
Forestomach papilloma Forestomach None (spontaneous) 2 0 - low
Gallbladder cyst Gallbladder None (spontaneous) 2 0
Gallbladder hyperplasia Gallbladder None (spontaneous) 3 0 - observed
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous) 2 0
Gastrointestinal tract carcinoma Gastrointestinal tract Chemical/Drug 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous) 2 0
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous) 3 0 - very low
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Kidney adenoma Kidney None (spontaneous) 2 0
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus None (spontaneous) 1 0
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus Chemical/Drug 2 0 - 39
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug 1 11.11
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous) 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug 1 0
Leukocyte leukemia Leukocyte Chemical/Drug 1 21
Leukocyte leukemia Leukocyte None (spontaneous) 3 0 - 7.0
Leukocyte leukemia Leukocyte Virus 2 0
Leukocyte lymphoma Leukocyte None (spontaneous) 3 observed - moderate
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous) 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous) 2 0
Liver hepatoma Liver None (spontaneous) 3 0 - high
Liver tumor Liver Chemical/Drug 1 2.7
Lung adenoma Lung Chemical/Drug 2 6.7 - 10
Lung adenoma Lung None (spontaneous) 8 0 - low
Lung carcinoma Lung Chemical/Drug 1 0
Lung hyperplasia Lung None (spontaneous) 3 0 - observed
Lung tumor Lung None (spontaneous) 1 1
Lung tumor Lung Chemical/Drug 1 10
Lymph node cyst Lymph node None (spontaneous) 2 0
Lymph node hyperplasia Reticulocyte None (spontaneous) 2 0
Lymphoid tissue lymphoma Lymph node None (spontaneous) 1 observed
Mammary gland hyperplasia Mammary gland None (spontaneous) 2 observed - 33
Mammary gland tumor Mammary gland None (spontaneous) 2 1 - low
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous) 2 0 - very low
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous) 1 0
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous) 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous) 1 very low
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous) 1 0
Myoepithelial cell myoepithelioma Lung None (spontaneous) 2 0
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous) 2 0
Nail squamous cell carcinoma Nail None (spontaneous) 2 0 - very low
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous) 1 high
Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell None (spontaneous) 1 0
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous) 1 low
Ovary adenoma Ovary None (spontaneous) 1 very low
Ovary cyst - bursal Ovary None (spontaneous) 3 observed - low
Ovary hyperplasia - epithelial Ovary None (spontaneous) 1 0
Ovary papilloma Ovary None (spontaneous) 1 observed
Ovary tumor Ovary Chemical/Drug 1 2.7
Ovary tumor - tubulostromal Ovary None (spontaneous) 1 very low
PNS - Nerve sheath tumor Ear None (spontaneous) 2 0
PNS - Nerve sheath tumor Skin None (spontaneous) 2 0
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous) 2 0
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous) 5 observed
Pancreas hyperplasia Pancreas None (spontaneous) 1 observed
Pituitary gland adenoma Pituitary gland None (spontaneous) 2 observed
Pituitary gland tumor Pituitary gland None (spontaneous) 3 observed - 33
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous) 1 0
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous) 2 0
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous) 2 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous) 2 0
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous) 2 0
Skin hyperplasia - epithelial Ear None (spontaneous) 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous) 2 0
Skin tumor Skin None (spontaneous) 2 35 - 38
Skin tumor Skin Chemical/Drug 1 46
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous) 3 0 - very low
Stomach - Glandular cyst Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous) 2 low
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous) 2 low
Stomach - Glandular polyp Stomach - Glandular None (spontaneous) 2 0
Tail hyperplasia Tail None (spontaneous) 1 observed
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell None (spontaneous) 2 observed
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous) 2 low
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous) 2 0
Ureter hyperplasia Muscle - Smooth None (spontaneous) 2 0
Ureter polyp Ureter None (spontaneous) 2 0
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous) 2 0
Urinary bladder papilloma Urinary bladder None (spontaneous) 2 0
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous) 4 observed - moderate
Uterus adenoma Uterus None (spontaneous) 1 0
Uterus fibropapilloma Uterus None (spontaneous) 1 0
Vagina hyperplasia Vagina None (spontaneous) 1 observed
Vagina papilloma Vagina None (spontaneous) 1 0
Vagina squamous cell carcinoma Vagina None (spontaneous) 1 observed
Vulva squamous cell carcinoma Vulva None (spontaneous) 1 0
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug 1 5.3
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=37
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/C57L.shtml
JAX Mice http://jaxmice.jax.org/strain/000668.html