Strain SummaryC57BL/6J

Strain Name

C57BL/6J

Strain Type(s)

inbred

Strain Synonym(s)

B6  •  B/6  •  B6J  •  B6 WT  •  Bl/6  •  Black 6  •  C57  •  C57/B16  •  C57/Bl  •  C57BL  •  C57/Bl6  •  C57 BL/6  •  C57BL/6  •  C57BL/6 from Jackson Laboratory  •  C57/Bl 6J  •  C57Bl/6J  •  C57BL6/J  •  C57BL/6J (F129+51)  •  C57BL/6J, H-2b  •  C57BL/6J inbred WT  •  C57BL/6J+/+  •  C57BL/6J (UW)  •  C57BL/6J wild-type  •  C57 Black  •  C57 black subline 6  •  control  •  Ctr  •  p53+/+  •  p53 wild-type (+/+)  •  p21+/+p27+/+  •  wild type  •  wild-type  •  wild-type C57BL/6J  •  wild-type (WT)  •  Wild-type (WT) C57BL/6J  •  WT  •  WT-Control  •  WT-CR

Models

567 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Adipose tissue - White lipoma Adipose tissue - White

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma Scrotum

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Adipose tissue lipoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adipose tissue lipoma - pedunculated Adipose tissue

0

very low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Cortex adenoma Adrenal gland - Cortex

0 - observed

0

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Cortex normal tissue (control) Adrenal gland - Cortex

not applicable

References: Mikaelian I, Personal Communication 2004;():

2 pathology image(s)

Adrenal gland - Medulla normal tissue (control) Adrenal gland - Medulla

not applicable

not applicable

References: Mikaelian I, Personal Communication 2004;():

6 pathology image(s)

Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Medulla pheochromocytoma - malignant Adrenal gland - Medulla

1

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell

0 - observed

0

References: Mikaelian I, Personal Communication 2004;():   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

1 pathology image(s)

Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell calorie restricted

0 - 2.0

0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell

moderate

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - nodular Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Adrenal gland hyperplasia - spindle cell Adrenal gland

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Adrenal gland tumor - carcinoid Adrenal gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel - Aorta metaplasia - cartilaginous Blood vessel - Aorta

0

References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5

Blood vessel hemangioma Liver

2

6

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Blood vessel hemangioma Blood vessel

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Spleen

1

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangioma - capillary Blood vessel

observed

References: Booth CJ, Lab Anim Sci 1995 Oct;45(5):497-502

Blood vessel hemangioma - capillary Liver

observed

References: Booth CJ, Lab Anim Sci 1995 Oct;45(5):497-502

Blood vessel hemangioma - cavernous Ovary

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Blood vessel hemangioma - cavernous Spleen

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Blood vessel hemangiosarcoma Spleen

0

4.0

observed

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Liver

0 - observed

0 - 2

observed

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10   ⋅   McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Spleen calorie restricted

0

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Blood vessel hemangiosarcoma Liver calorie restricted

0

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Blood vessel hemangiosarcoma Blood vessel

0

0

4

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Blood vessel cesium-137

0

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Blood vessel hemangiosarcoma Uterus

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Ovary

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Skin

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel hemangiosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Blood vessel neoplasm Blood vessel

2

4

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Blood vessel normal tissue (control) Blood vessel

not applicable

References: Mikaelian I, Personal Communication 2004;():

5 pathology image(s)

Blood vessel tumor (Unspecified organ) (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Bone - Vertebral column - Vertebra osteosarcoma Bone - Vertebral column - Vertebra

1

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Bone - Vertebral column - Vertebra osteosarcoma - chondroblastic Bone - Vertebral column - Vertebra

observed

References: Mikaelian I, Personal Communication 2004;():

7 pathology image(s)

Bone hyperplasia Bone

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone lesion - fibro-osseous Bone

0 - 13.33

0

0 - 6.9

References: Berndt A, Exp Mol Pathol 2015 Nov 14;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Bone marrow normal tissue (control) Bone marrow

not applicable

References: Mikaelian I, Personal Communication 2004;():

6 pathology image(s)

Bone neoplasm Bone

2

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Bone osteosarcoma Bone

observed

observed

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2003;():

1 pathology image(s)

CNS - Brain - Choroid plexus normal tissue (control) CNS - Brain - Choroid plexus

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

4 pathology image(s)

CNS - Brain - Ependyma normal tissue (control) CNS - Brain - Ependyma

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

CNS - Brain - Glial cell normal tissue (control) CNS - Brain - Glial cell

not applicable

References: Mikaelian I, Personal Communication 2003;():

3 pathology image(s)

CNS - Brain - Neuron normal tissue (control) CNS - Brain - Neuron

not applicable

References: Mikaelian I, Personal Communication 2004;():

2 pathology image(s)

CNS - Brain glioma CNS - Brain

0

References: Harris MA, Cancer Res 2008 Dec 15;68(24):10051-9

CNS - Brain normal tissue (control) CNS - Brain

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

CNS - Spinal cord normal tissue (control) CNS - Spinal cord

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Connective tissue - Cartilage - Articular hyperplasia Limb - Hindlimb

0

References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5

Connective tissue - Cartilage hyperplasia Bone - Sternum

0

References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5

Connective tissue - Cartilage hyperplasia Ear - Outer ear

0

References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5

Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast

4

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Connective tissue - Fibroblast fibrosarcoma Uterus

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Connective tissue - Fibroblast fibrosarcoma Skin

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Connective tissue - Fibroblast fibrosarcoma Perirenal tissue

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Connective tissue - Fibroblast fibrosarcoma Ear

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Dendritic cell normal tissue (control) Lymph node

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Epididymis cyst Epididymis

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Epididymis normal tissue (control) Epididymis

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Erythrocyte leukemia - erythroleukemia Spleen

0

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Erythrocyte leukemia - erythroleukemia Liver

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Erythrocyte leukemia - erythroleukemia Spleen calorie restricted

3.3

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Erythrocyte leukemia - erythroleukemia Liver calorie restricted

3.3

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Erythrocyte neoplasm Erythrocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Esophagus dysplasia Esophagus Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus hyperplasia Esophagus

0

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Esophagus hyperplasia Esophagus zinc-deficient

observed

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Esophagus hyperplasia Esophagus Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus hyperplasia Esophagus Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed - 100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus lesion Esophagus Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus lesion Esophagus Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus normal tissue (control) Esophagus

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

9 pathology image(s)

Esophagus papilloma Esophagus Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus papilloma Esophagus Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus squamous cell carcinoma Esophagus N-amyl-N-methylnitrosoamine (AMN)

observed

References: Kurooka M, Cancer Lett 1998 May 15;127(1-2):55-61

Esophagus squamous cell carcinoma Esophagus Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus squamous cell carcinoma Esophagus Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed - 100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus tumor Esophagus

0

References: Kurooka M, Cancer Lett 1998 May 15;127(1-2):55-61

Esophagus tumor Esophagus N-amyl-N-methylnitrosoamine (AMN)

100

References: Kurooka M, Cancer Lett 1998 May 15;127(1-2):55-61

Esophagus tumor Esophagus N-nitrosomethylbenzylamine (NMBA)   ⋅   zinc-deficient

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Esophagus tumor Esophagus N-nitrosomethylbenzylamine (NMBA)

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Esophagus tumor Esophagus Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Esophagus tumor Esophagus Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Eye - Conjunctiva normal tissue (control) Eye - Conjunctiva

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Eye - Cornea normal tissue (control) Eye - Cornea

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

7 pathology image(s)

Eye - Eyelid normal tissue (control) Eye - Eyelid

not applicable

References: Mikaelian I, Personal Communication 2003;():

1 pathology image(s)

Eye - Harderian gland adenoma Eye - Harderian gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)

Eye - Harderian gland neoplasm Eye - Harderian gland

0

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Eye - Retina normal tissue (control) Eye - Retina

not applicable

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Eye normal tissue (control) Eye

not applicable

References: Mikaelian I, Personal Communication 2002;():

2 pathology image(s)

Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach N-nitrosomethylbenzylamine (NMBA)   ⋅   zinc-deficient

13

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach N-nitrosomethylbenzylamine (NMBA)

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Forestomach hyperplasia Forestomach zinc-deficient

observed

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Forestomach hyperplasia Forestomach

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Forestomach hyperplasia - papillary Forestomach

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach lesion Forestomach Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Forestomach lesion Forestomach Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Forestomach normal tissue (control) Forestomach

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Forestomach papilloma Forestomach

very low

very low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Forestomach tumor Forestomach N-nitrosomethylbenzylamine (NMBA)   ⋅   zinc-deficient

13

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Forestomach tumor Forestomach N-nitrosomethylbenzylamine (NMBA)

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Forestomach tumor Forestomach Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Forestomach tumor Forestomach Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Gallbladder cyst Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder hyperplasia Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gallbladder hyperplasia - papillary Gallbladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Gastrointestinal tract tumor Gastrointestinal tract

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Gingiva squamous cell carcinoma - well differentiated Gingiva

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

6 pathology image(s)

Heart normal tissue (control) Heart

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

4 pathology image(s)

Intestine - Large Intestine - Cecum adenoma - flat Intestine - Large Intestine - Cecum (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum dextran sulfate sodium (DSS)

observed

References: Mahler M, Am J Physiol 1998 Mar;274(3 Pt 1):G544-51

Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Colon - Distal adenocarcinoma Intestine - Large Intestine - Colon - Distal

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

observed

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50

Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal azoxymethane (AOM)

0

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50

Intestine - Large Intestine - Colon - Medial adenocarcinoma Intestine - Large Intestine - Colon - Medial

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Large Intestine - Colon - Medial adenoma Intestine - Large Intestine - Colon - Medial

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Large Intestine - Colon - Proximal adenocarcinoma Intestine - Large Intestine - Colon - Proximal

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Large Intestine - Colon - Proximal adenoma Intestine - Large Intestine - Colon - Proximal

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal azoxymethane (AOM)

0

References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50

Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)

observed

observed

References: Mahler M, Am J Physiol 1998 Mar;274(3 Pt 1):G544-51

Intestine - Large Intestine - Colon lesion Intestine - Large Intestine - Colon Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Intestine - Large Intestine - Colon lesion Intestine - Large Intestine - Colon Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Intestine - Large Intestine - Colon normal tissue (control) Intestine - Large Intestine - Colon

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

37 pathology image(s)

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon 1,2-dimethylhydrazine (DMH)

observed

References: Rosenberg DW, Cancer Lett 1995 Jun 8;92(2):209-14

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon azoxymethane (AOM)

observed

References: Shattuck-Brandt RL, Gastroenterology 2000 Feb;118(2):337-45   ⋅   Shattuck-Brandt RL, Mol Carcinog 1999 Mar;24(3):177-87

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon troglitazone

0

References: Saez E, Nat Med 1998 Sep;4(9):1058-61

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

100

References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon AIN-76A

0 - 6.67

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon New western diet (NWD) TD.96096

0 - 26.67

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

0 - 4.55

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

0 - 27.78

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon choline-enriched   ⋅   New western diet (NWD) TD.96096

5.56 - 10

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon methionine-enriched   ⋅   New western diet (NWD) TD.96096

11.11 - 18.75

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon New western diet (NWD) TD.96096   ⋅   high fiber

0 - 29.41

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine

0

References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20

Intestine - Large Intestine tumor Intestine - Large Intestine dextran sulfate sodium (DSS)   ⋅   azoxymethane (AOM)

100

References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24

Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland

0

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

5 pathology image(s)

Intestine - Small Intestine - Duodenum adenocarcinoma Intestine - Small Intestine - Duodenum

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum

0

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Duodenum lesion Intestine - Small Intestine - Duodenum N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)

observed

References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81

Intestine - Small Intestine - Duodenum normal tissue (control) Intestine - Small Intestine - Duodenum

not applicable

not applicable

References: Mikaelian I, Personal Communication 2004;():

14 pathology image(s)

Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Ileum adenocarcinoma Intestine - Small Intestine - Ileum

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Small Intestine - Ileum normal tissue (control) Intestine - Small Intestine - Ileum

not applicable

References: Paoni NF, Physiol Genomics 2003 Nov 11;15(3):228-35

Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum adenocarcinoma Intestine - Small Intestine - Jejunum

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum

0

0 - observed

References: Sundberg J, Personal Communication 1997;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Intestine - Small Intestine adenocarcinoma Intestine - Small Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine adenoma - tubular Intestine - Small Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine normal tissue (control) Intestine - Small Intestine

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

40 pathology image(s)

Intestine - Small Intestine tumor Intestine - Small Intestine

0

References: Williams JL, Biochem Biophys Res Commun 2004 Jan 16;313(3):784-8

Intestine - Small Intestine tumor Intestine - Small Intestine 2-(acetyloxy)benzoic acid 4-(nitrooxy methyl)phenyl ester) (NO-ASA)

0

References: Williams JL, Biochem Biophys Res Commun 2004 Jan 16;313(3):784-8

Intestine - Small Intestine tumor Intestine - Small Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine AIN-76A

0 - 26.67

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine New western diet (NWD) TD.96096

0 - 26.67

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

5.56 - 15.38

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

7.14 - 26.09

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine choline-enriched   ⋅   New western diet (NWD) TD.96096

10 - 33.33

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine methionine-enriched   ⋅   New western diet (NWD) TD.96096

11.11 - 25

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine - Small Intestine tumor Intestine - Small Intestine New western diet (NWD) TD.96096   ⋅   high fiber

0 - 11.76

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenocarcinoma Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine AIN-76A

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine choline-enriched   ⋅   New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine methionine-enriched   ⋅   New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma Intestine New western diet (NWD) TD.96096   ⋅   high fiber

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine adenoma - tubular Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine AIN-76A

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine choline-enriched   ⋅   New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine methionine-enriched   ⋅   New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma Intestine New western diet (NWD) TD.96096   ⋅   high fiber

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine AIN-76A

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine methionine-enriched   ⋅   New western diet (NWD) TD.96096

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine New western diet (NWD) TD.96096   ⋅   high fiber

2

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine carcinoma - invasive Intestine choline-enriched   ⋅   New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine AIN-76A

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine choline-enriched   ⋅   New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine methionine-enriched   ⋅   New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine lesion Intestine New western diet (NWD) TD.96096   ⋅   high fiber

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine neoplasm Intestine

0

4

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Intestine normal tissue (control) Intestine

not applicable

References: Mikaelian I, Personal Communication 2002;():

6 pathology image(s)

Intestine polyp Intestine

0

observed

References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96   ⋅   Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8

Intestine tumor Intestine

0 - observed

References: Kucherlapati MH, PLoS One 2013;8(7):e68817   ⋅   Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96

Intestine tumor Intestine BEZ235 (NVP-BEZ235-AN)

0

References: Kucherlapati MH, PLoS One 2013;8(7):e68817

Intestine tumor Intestine (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine AIN-76A

0 - 26.67

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine New western diet (NWD) TD.96096

0 - 53.33

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

5.56 - 15.38

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

7.14 - 44.44

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine choline-enriched   ⋅   New western diet (NWD) TD.96096

13.04 - 33.33

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine methionine-enriched   ⋅   New western diet (NWD) TD.96096

22.22 - 37.5

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Intestine tumor Intestine New western diet (NWD) TD.96096   ⋅   high fiber

5.88 - 35.29

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Kidney - Cortex cyst Kidney - Cortex

7.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Kidney - Cortex cyst Kidney - Cortex calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Kidney - Renal tubule cyst Kidney - Renal tubule

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Kidney adenoma Kidney

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Kidney cyst Kidney

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Kidney cyst - macrocyst Kidney

2

4

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Kidney cyst - microcyst Kidney

4

4

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Kidney lesion Kidney

10

2.0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Kidney lesion Kidney calorie restricted

0 - 2.0

2.0 - 4.0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Kidney metaplasia - osseous Kidney

0

2

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Kidney normal tissue (control) Kidney

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

7 pathology image(s)

Kidney transitional cell hyperplasia Kidney

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Kidney tumor - round cell Kidney

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Kidney tumor - round cell Kidney calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Lymphocyte - B-lymphocyte tumor Leukocyte - Lymphocyte - B-lymphocyte jet-lag light cycle

observed

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus gamma-radiation

observed

100

References: Bueno MJ, Cancer Cell 2008 Jun;13(6):496-506   ⋅   Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42

Leukocyte - Lymphocyte - T-lymphocyte normal tissue (control) Thymus gamma-radiation

not applicable

References: Bueno MJ, Cancer Cell 2008 Jun;13(6):496-506

Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte

0 - 2

1

6

References: Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():

Leukocyte - Lymphocyte leukemia - lymphocytic Lung

7.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte leukemia - lymphocytic Spleen

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte leukemia - lymphocytic Liver

7.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte leukemia - lymphocytic Lung calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte leukemia - lymphocytic Spleen calorie restricted

6.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte leukemia - lymphocytic Liver calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

50

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte - Lymphocyte normal tissue (control) Lymph node

not applicable

References: Mikaelian I, Personal Communication 2004;():

7 pathology image(s)

Leukocyte - Lymphocyte normal tissue (control) Spleen - White pulp

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte

0 - 9

0 - 51

observed

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Abdominal cavity

7.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen

0 - 15

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver

0 - 6

12

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10   ⋅   McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Abdominal cavity calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen calorie restricted

10

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver calorie restricted

23

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node - Mesenteric

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Uterus

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

2 pathology image(s)

Leukocyte - Monocyte - Macrophage - Kupffer cell sarcoma Liver (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Liver

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte - Myelocyte (Granulocyte) normal tissue (control) Spleen

not applicable

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Leukocyte leukemia Leukocyte

0 - 16

0

2.7

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80   ⋅   Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70   ⋅   Myers DD, Life Sci 1970;9(Pt II):1071-80

Leukocyte leukemia Leukocyte Friend leukemia virus - "regressing" (RFV)

0

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte leukemia Leukocyte Friend leukemia virus - "conventional" (CFV)

0

References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104

Leukocyte leukemia Leukocyte 1-ethyl-1-nitrosourea (ENU)

20

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Leukocyte leukemia Leukocyte cesium-137

0

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Leukocyte lymphoma Leukocyte

0 - 57

0 - 50

observed

observed

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80   ⋅   Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Fong LY, Cancer Res 2003 Jan 1;63(1):186-95   ⋅   Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Leukocyte lymphoma Leukocyte zinc-deficient

0

References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95

Leukocyte lymphoma Kidney

0 - 14

6.0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Lung

0 - 20

8.0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Thymus

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte lymphoma Spleen

0 - 12

2.0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Liver

6 - 8.0

6.0 - 8

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10   ⋅   McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Pancreas

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte lymphoma Lymph node

15

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte lymphoma Kidney calorie restricted

0 - 6.7

0 - 2.0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Lung calorie restricted

0

2.0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Thymus calorie restricted

3.3

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte lymphoma Spleen calorie restricted

0 - 6.7

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Liver calorie restricted

0 - 10

2.0 - 8.0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Pancreas calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte lymphoma Lymph node calorie restricted

10

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Leukocyte lymphoma Leukocyte cesium-137

5.3

21

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Leukocyte lymphoma Heart

0

0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma Heart calorie restricted

0

0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Leukocyte lymphoma - lymphosarcoma Leukocyte

0

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Leukocyte lymphoma - lymphosarcoma Leukocyte cesium-137

5.3

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Leukocyte lymphoma - non-Hodgkin Leukocyte (see notes regarding diet)

observed - 3.93

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Leukocyte lymphoma - non-Hodgkin Leukocyte AIN-76A

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Leukocyte neoplasia Leukocyte

67

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct adenoma Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Bile duct cyst - macrocyst Liver - Bile duct

0

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Liver - Bile duct hyperplasia Liver - Bile duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver - Hepatocyte foci - basophilic Liver - Hepatocyte N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Hepatocyte foci - basophilic Liver - Hepatocyte phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver - Hepatocyte foci - eosinophilic Liver - Hepatocyte phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver adenoma Liver

1

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Liver carcinoma Liver

0

2.0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Liver carcinoma Liver calorie restricted

0

0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Liver cyst Liver

0

0

3

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Liver cyst Liver calorie restricted

0

0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Liver cyst - macrocyst Liver

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Liver cystadenoma Liver

0

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Liver cystadenoma Liver cesium-137

0

14

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Liver foci - clear cell Liver

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Liver foci - eosinophilic Liver

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Liver foci - vacuolated cell Liver

0

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Liver hepatoblastoma Liver

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Liver hepatoblastoma Liver (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Liver hepatocellular adenoma Liver phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver hepatocellular adenoma Liver

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Liver hepatocellular carcinoma Liver

0

0 - 8.8

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10   ⋅   Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924   ⋅   Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85   ⋅   Sundberg J, MGI Direct Data Submission 2007;():

Liver hepatocellular carcinoma Liver N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver hepatocellular carcinoma Liver phenobarbital (PB)   ⋅   N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)

observed

References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34

Liver hepatocellular carcinoma Liver aflatoxin B1 (AFB1) (AFB1)

26.67

References: McGlynn KA, Cancer Res 2003 Aug 1;63(15):4594-601

Liver hepatocellular carcinoma Liver tricaprylin

0

References: McGlynn KA, Cancer Res 2003 Aug 1;63(15):4594-601

Liver hepatocellular carcinoma Liver jet-lag light cycle

observed

observed

8.75

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

Liver hepatocellular carcinoma Liver high saturated fat, high sucrose

observed

References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588

Liver hepatoma Liver

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Liver hyperplasia Liver

3

15.45

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Liver hyperplasia Liver jet-lag light cycle

75

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

Liver lesion Liver

0

12

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Liver lesion Liver calorie restricted

0 - 8.0

4.0 - 26

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Liver lesion Liver Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Liver lesion Liver Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Liver neoplasm Liver

0

0 - 4

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Liver normal tissue (control) Liver

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

12 pathology image(s)

Liver tumor Liver 7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Kalkuhl A, Hepatology 1998 Apr;27(4):1081-8

Liver tumor Liver

0 - 30

References: Davis LM, Carcinogenesis 1994 Aug;15(8):1637-45   ⋅   Schneider JL, Aging Cell 2015 Apr;14(2):249-64   ⋅   Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7

Liver tumor Liver (see notes regarding diet)

observed - 2.81

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Liver tumor Liver AIN-76A

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Liver tumor Liver methionine-enriched   ⋅   New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Liver tumor Liver Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Liver tumor Liver Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Lung - Alveolus adenoma Lung - Alveolus (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Lung - Alveolus carcinoma Lung - Alveolus (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Lung - Bronchiole adenoma Lung - Bronchiole (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Lung - Bronchiole carcinoma Lung - Bronchiole (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Lung adenocarcinoma Lung

3

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Lung adenoma Lung urethane (ethyl carbamate)

57 - 100

observed - 48

References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6   ⋅   Malkinson AM, J Natl Cancer Inst 1985 Nov;75(5):971-4   ⋅   Thaete LG, Cancer Lett 1991 Dec 9;61(1):15-20

Lung adenoma Lung 1-ethyl-1-nitrosourea (ENU)

7.1

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

Lung adenoma Lung

0

observed - very low

1

0

References: Berndt A, Cancer Res 2011 Sep 1;71(17):5779-91   ⋅   Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70   ⋅   Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

9 pathology image(s)

Lung adenoma Lung urethane (ethyl carbamate)   ⋅   butylated hydroxytoluene (BHT)

54

References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6

Lung adenoma Lung calorie restricted

0

0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Lung carcinoma Lung

11

References: Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85

Lung carcinoma Lung N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)

0

References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38

Lung hyperplasia Lung

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lung lesion Lung Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Lung lesion Lung Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Lung neoplasm Lung

2

8

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Lung normal tissue (control) Lung

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

8 pathology image(s)

Lung tumor Lung

0 - 3

0 - 1

1

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8   ⋅   Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831   ⋅   Ryan J, J Natl Cancer Inst 1987 Dec;79(6):1351-7

Lung tumor Lung uranium ore dust

0

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung tumor Lung radon

0

References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung tumor Lung urethane (ethyl carbamate)

60 - 100

observed - 100

57

References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93   ⋅   Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32   ⋅   Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8

Lung tumor Lung urethane (ethyl carbamate)   ⋅   butylated hydroxytoluene (BHT)

100

References: Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32

Lung tumor Lung (see notes regarding diet)

observed - 4.21

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Lung tumor Lung AIN-76A

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Lung tumor Lung Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Lung tumor Lung Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Lung tumor - malignant Lung

2.0

4.0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Lung tumor - malignant Lung calorie restricted

0

2.0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Lymph node cyst Lymph node

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymph node hyperplasia Reticulocyte

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Lymph node normal tissue (control) Lymph node

not applicable

References: Mikaelian I, Personal Communication 2003;():

1 pathology image(s)

Mammary gland adenocarcinoma Mammary gland

0 - 1

0

References: Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831

Mammary gland adenocarcinoma - intraductal Mammary gland

observed

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Mammary gland neoplasm Mammary gland

0

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Mammary gland normal tissue (control) Mammary gland

not applicable

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

14 pathology image(s)

Mammary gland tumor Mammary gland

1

0 - 1

References: Bradlow HL, Proc Natl Acad Sci U S A 1985 Sep;82(18):6295-9   ⋅   Felicio LS, Exp Gerontol 1980;15(2):139-43   ⋅   Staats J, Companion to Mouse News Lett No. 29 1963;():

Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Intestine - Small Intestine - Brunner's gland

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Mesodermal cell/mesoblast sarcoma Liver

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Mesodermal cell/mesoblast sarcoma Peritoneal cavity

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Seminal vesicle

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma Urinary bladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesodermal cell/mesoblast sarcoma - round cell Lung

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Mesodermal cell/mesoblast sarcoma - round cell Liver

7.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Mesodermal cell/mesoblast sarcoma - round cell Lymph node

7.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Mesodermal cell/mesoblast sarcoma - round cell Lung calorie restricted

3.3

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Mesodermal cell/mesoblast sarcoma - round cell Liver calorie restricted

6.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Mesodermal cell/mesoblast sarcoma - round cell Lymph node calorie restricted

6.7

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Mesothelium foci Mesothelium crocidolite asbestos

18.18

References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94

Mesothelium mesothelioma Mesothelium crocidolite asbestos

86.67 - 100

References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94

Mesothelium mesothelioma Mesothelium

0

References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94

Mesothelium mesothelioma - malignant - sarcomatoid Mesothelium crocidolite asbestos

18.18

References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94

Mesothelium tumor - benign Mesothelium crocidolite asbestos

45.45

References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94

Mouth - Oral mucosa cyst Mouth - Oral mucosa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyoma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Muscle - Smooth

0

0

3

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Seminal vesicle

4

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Colon

1

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Smooth leiomyosarcoma (Unspecified organ) (see notes regarding diet)

observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Muscle - Striated - Skeletal normal tissue (control) Muscle - Striated - Skeletal

not applicable

not applicable

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal

0

References: Sher RB, PLoS One 2011;6(8):e23498

Myoepithelial cell myoepithelioma Lung

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Myoepithelial cell myoepithelioma Mammary gland

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Nail dysplasia Nail

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Nail squamous cell carcinoma Nail

0

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

4 pathology image(s)

Nerve normal tissue (control) Nerve

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Oral cavity normal tissue (control) Oral cavity

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

12 pathology image(s)

Ovary - Follicle cyst - follicular Ovary - Follicle

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Granulosa cell tumor Ovary - Granulosa cell

0 - 2

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Granulosa cell tumor Ovary - Granulosa cell cesium-137

5.3

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Ovary - Luteal cell tumor Ovary - Luteal cell

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary - Sex cord stromal cell adenoma - tubulostromal Ovary - Sex cord stromal cell

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)

Ovary adenoma Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary cyst Ovary

4

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Ovary cyst - bursal Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary cystadenoma Ovary

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Ovary cystadenoma Ovary cesium-137

42

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Ovary hyperplasia - epithelial Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ovary luteoma Ovary

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Ovary neoplasm Ovary

1

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Ovary tumor Ovary

0

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Ovary tumor Ovary cesium-137

47

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

Ovary tumor Ovary jet-lag light cycle

observed

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

Ovary tumor - tubulostromal Ovary

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Oviduct hyperplasia Oviduct

observed

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Oviduct normal tissue (control) Oviduct

not applicable

References: Mikaelian I, Personal Communication 2004;():

6 pathology image(s)

PNS - Nerve sheath tumor Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

PNS - Nerve sheath tumor Skin

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Duct adenoma Pancreas - Duct

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell

0

References: Christofori G, Nature 1994 Jun 2;369(6479):414-8

Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Pancreas neoplasm Pancreas

0

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Pancreas normal tissue (control) Pancreas

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

5 pathology image(s)

Pancreas tumor Pancreas jet-lag light cycle

observed

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

Peritoneum - Mesentery hyperplasia Peritoneum - Mesentery

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

1 pathology image(s)

Peyer's patch normal tissue (control) Peyer's patch

not applicable

References: Mikaelian I, Personal Communication 2004;():

5 pathology image(s)

Pituitary gland - Pars distalis adenocarcinoma Pituitary gland - Pars distalis

1

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

2 pathology image(s)

Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis

20 - 31

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10   ⋅   McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis calorie restricted

3.3

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Pituitary gland - Pars distalis cyst - microcyst Pituitary gland - Pars distalis

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Pituitary gland - Pars distalis hyperplasia - focal Pituitary gland - Pars distalis

12

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Pituitary gland - Pars distalis tumor Pituitary gland - Pars distalis

0 - 83

References: Schechter JE, Anat Rec 1981 Mar;199(3):423-32

Pituitary gland - Pars intermedia adenoma Pituitary gland - Pars intermedia

0 - observed

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10   ⋅   Sundberg J, MGI Direct Data Submission 2007;():

Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia

4

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Pituitary gland adenoma Pituitary gland

0

6

References: Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Pituitary gland carcinoma Pituitary gland

2

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Pituitary gland cyst - microcyst Pituitary gland

2

2

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Pituitary gland hyperplasia Pituitary gland

observed

References: Felicio LS, Exp Gerontol 1980;15(2):139-43

Pituitary gland hyperplasia - focal Pituitary gland

0

0

References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10

Pituitary gland neoplasm Pituitary gland

4 - 7

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Pituitary gland tumor Pituitary gland

0 - 61

sporadic

observed

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105   ⋅   Felicio LS, Exp Gerontol 1980;15(2):139-43

Pituitary gland tumor Pituitary gland ovariectomy

very low

References: Felicio LS, Exp Gerontol 1980;15(2):139-43

Placenta normal tissue (control) Placenta

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

4 pathology image(s)

Preputial/Clitoral gland (sex not specified) normal tissue (control) Preputial/Clitoral gland (sex not specified)

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

5 pathology image(s)

Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Prostate gland normal tissue (control) Prostate gland

not applicable

References: Mikaelian I, Personal Communication 2004;():

2 pathology image(s)

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

observed

References: Pathbase web site, University of Cambridge, MGI Direct Data Submission 2009;():

8 pathology image(s)

Salivary gland - Parotid hyperplasia Salivary gland - Parotid

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Salivary gland normal tissue (control) Salivary gland

not applicable

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

9 pathology image(s)

Seminal vesicle normal tissue (control) Seminal vesicle

not applicable

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Skin - Dorsal region adenoma - sebaceous Skin - Dorsal region

observed

References: Sundberg J, Personal Communication 1997;():

4 pathology image(s)

Skin - Dorsal region papilloma Skin - Dorsal region

observed

References: Sundberg J, Personal Communication 1997;():

Skin - Dorsal region tumor Skin - Dorsal region mouse papillomavirus (MmuPV1)

0

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis cyst - inclusion Skin - Epidermis

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin - Epidermis hamartoma Skin - Epidermis

observed

References: Mikaelian I, Personal Communication 2002;():

1 pathology image(s)

Skin - Epidermis hyperplasia Skin - Epidermis

observed

References: Sundberg J, Personal Communication 1997;():

Skin - Facial region tumor Skin - Facial region mouse papillomavirus (MmuPV1)

0

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Hair follicle hyperplasia Skin - Hair follicle

observed

References: Sundberg J, Personal Communication 1997;():

Skin - Tail tumor Skin - Tail mouse papillomavirus (MmuPV1)

0

References: Sundberg JP, PLoS One 2014;9(12):e113582

Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia Skin

observed

References: Sundberg J, Personal Communication 1997;():

8 pathology image(s)

Skin hyperplasia - epithelial Ear

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin hyperplasia - epithelial Eye - Eyelid

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Skin lesion Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

observed

References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7

Skin lesion Skin mouse papillomavirus (MmuPV1)

0

References: Sundberg JP, PLoS One 2014;9(12):e113582

6 pathology image(s)

Skin normal tissue (control) Skin

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

64 pathology image(s)

Skin papilloma Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

very high

References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7

Skin squamous cell carcinoma Skin

observed

1

References: Pathbase web site, University of Cambridge, MGI Direct Data Submission 2009;():   ⋅   Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

1 pathology image(s)

Skin tumor Skin 12-O-tetradecanoylphorbol-13-acetate (TPA)   ⋅   7,12-dimethylbenz[a]anthracene (DMBA)

42

References: Sundberg JP, Mol Carcinog 1997 SEP;20(1):19-32

Skin tumor Skin

0

11

References: Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85   ⋅   Staats J, Companion to Mouse News Lett No. 21 1959;():

Spleen normal tissue (control) Spleen

not applicable

References: Mikaelian I, Personal Communication 2004;():

21 pathology image(s)

Spleen tumor Spleen

0

6.0

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Spleen tumor Spleen calorie restricted

0 - 4.0

2.0 - 10

References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112

Spleen tumor - round cell Spleen

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Spleen tumor - round cell Spleen calorie restricted

0

References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8

Stomach - Epithelium hyperplasia - squamous Stomach - Epithelium

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Stomach - Glandular adenoma Stomach - Glandular

0

low

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular cyst - glandular Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia Stomach - Glandular

low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular

low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach - Glandular normal tissue (control) Stomach - Glandular

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Stomach - Glandular polyp Stomach - Glandular

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Stomach adenocarcinoma Stomach

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Stomach adenoma Stomach

0

References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54

Stomach adenoma - microadenoma Stomach AIN-76A

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach adenoma - microadenoma Stomach New western diet (NWD) TD.96096

0 - observed

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach adenoma - microadenoma Stomach New western diet (NWD) TD.96096   ⋅   vitamin D3 (1alpha,25-(OH)2-D3) (VD3)   ⋅   Calcium-enriched

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach adenoma - microadenoma Salivary gland New western diet (NWD) TD.96096   ⋅   Folic acid-enriched

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach adenoma - microadenoma Stomach choline-enriched   ⋅   New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach adenoma - microadenoma Stomach methionine-enriched   ⋅   New western diet (NWD) TD.96096

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach adenoma - microadenoma Stomach New western diet (NWD) TD.96096   ⋅   high fiber

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

Stomach normal tissue (control) Stomach

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

2 pathology image(s)

Stomach squamous cell papilloma Stomach

3

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Germ cell normal tissue (control) Testis - Germ cell

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell)

4

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis - Leydig cell (Interstitial cell) normal tissue (control) Testis - Leydig cell (Interstitial cell)

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell)

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Testis normal tissue (control) Testis

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Thymus normal tissue (control) Thymus

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

35 pathology image(s)

Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

Thyroid gland - Follicular cell hyperplasia Thyroid gland - Follicular cell

observed

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Thyroid gland adenoma Thyroid gland

observed

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

3 pathology image(s)

Thyroid gland hyperplasia - cystic Thyroid gland

low

0 - observed

References: Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Thyroid gland neoplasm Thyroid gland

0

0

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Tongue atypia Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue carcinoma in situ Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue dysplasia Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue dysplasia - high grade Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue hyperplasia Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue lesion Tongue Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue lesion Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

0 - 100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue normal tissue (control) Tongue

not applicable

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

15 pathology image(s)

Tongue papilloma Tongue Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue papilloma Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue squamous cell carcinoma Tongue Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue squamous cell carcinoma Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

observed - 100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Sites of Metastasis: Muscle - Striated - Skeletal

Tongue tumor Tongue Propylene glycol

0

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tongue tumor Tongue Propylene glycol   ⋅   4-nitroquinoline-1-oxide (4NQO)

100

References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13

Tooth dysplasia Tooth

observed

observed

observed

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg J, MGI Direct Data Submission 2007;():

8 pathology image(s)

Trachea normal tissue (control) Trachea

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

4 pathology image(s)

Ureter - Transitional cell hyperplasia Ureter - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter hyperplasia Ureter

observed

References: Sundberg J, MGI Direct Data Submission 2007;():

5 pathology image(s)

Ureter hyperplasia Muscle - Smooth

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Ureter polyp Ureter

very low

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Urinary bladder - Transitional cell normal tissue (control) Urinary bladder - Transitional cell

not applicable

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Urinary bladder normal tissue (control) Urinary bladder

not applicable

References: Mikaelian I, Personal Communication 2003;():   ⋅   Mikaelian I, Personal Communication 2004;():

6 pathology image(s)

Urinary bladder papilloma Urinary bladder

0

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium

observed - moderate

References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():   ⋅   Sundberg J, MGI Direct Data Submission 2007;():   ⋅   Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus - Endometrium normal tissue (control) Uterus - Endometrium

not applicable

References: Mikaelian I, Personal Communication 2004;():

3 pathology image(s)

Uterus adenoma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus fibropapilloma Uterus

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Uterus neoplasm Uterus

4

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

Uterus normal tissue (control) Uterus

not applicable

References: Mikaelian I, Personal Communication 2002;():   ⋅   Mikaelian I, Personal Communication 2004;():

4 pathology image(s)

Vagina normal tissue (control) Vagina

not applicable

References: Mikaelian I, Personal Communication 2004;():

1 pathology image(s)

Vagina papilloma Vagina

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

Vulva squamous cell carcinoma Vulva

0

References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():

(Unspecified organ) neoplasm (Unspecified organ)

35 - 43

38 - 50

References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105

(Unspecified organ) reticulum cell sarcoma (Unspecified organ)

9

References: Staats J, Companion to Mouse News Lett No. 21 1959;():

(Unspecified organ) tumor (Unspecified organ)

0 - 14

0 - 10

0 - low

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80   ⋅   Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924   ⋅   Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85   ⋅   Staats J, Companion to Mouse News Lett No. 29 1963;():   ⋅   Storer JB, J Gerontol 1966 Jul;21(3):404-9

(Unspecified organ) tumor (Unspecified organ) 1-ethyl-1-nitrosourea (ENU)

2.4

References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70

(Unspecified organ) tumor (Unspecified organ) cesium-137

58

36

References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80

(Unspecified organ) tumor (Unspecified organ) jet-lag light cycle

observed

References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924

(Unspecified organ) tumor (Unspecified organ) (see notes regarding diet)

observed - 14.47

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

(Unspecified organ) tumor (Unspecified organ) AIN-76A

observed - 6.67

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

(Unspecified organ) tumor (Unspecified organ) New western diet (NWD) TD.96096   ⋅   high fiber

0

References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92