Reference Detail

Help and Documentation

Reference Detail

Reference

Title:	Subcapsular cell hyperplasia and mast cell infiltration in the adrenal cortex of mice: comparative study in 7 inbred strains.
Authors:	Kim JS; Kubota H; Kiuchi Y; Doi K; Saegusa J
Journal:	Exp Anim
Volume:	46
Issue:	4
Year:	1997
Pages:	303-6
Abstract:	Subcapsular cell hyperplasia (SCH) in the adrenal cortex of aged mice (13-15 months old) was frequent in both sexes of BALB/c, C3H/He, DBA/2J and IQI/Jic mice and in the females of A/J and C57BL/6, although the incidence and severity of SCH were considerably different among mouse strains. Mast cells were closely associated with SCH in the A/J, BALB/c, C57BL/6, DBA/2J and IQI/Jic mice, but not in the C3H/He strain. Compared with other strains, IQI/Jic mice had a significantly larger number of mast cells in the adrenal glands. Our findings suggest that mast cells may participate in the development of SCH, and IQI/Jic would be suitable for studying the pathogenesis of SCH and the role of mast cells in this lesion.

Additional
Information
in MTB

Tumor Records (14)

Strains (7)

Other
Accession
IDs

J:44011 Mouse Genome Informatics

9353639 National Library of Medicine/PubMed